Eike Bormann
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View article: Risk factors, outcomes, and early prediction of cardiac surgery-associated acute kidney injury: a post hoc subgroup analysis of the Epidemiology of Surgery Associated Acute Kidney Injury study
Risk factors, outcomes, and early prediction of cardiac surgery-associated acute kidney injury: a post hoc subgroup analysis of the Epidemiology of Surgery Associated Acute Kidney Injury study Open
Overall, 25% of cardiac surgery patients developed CSA-AKI, and 33% of these patients experienced persistent CSA-AKI, which was associated with poor outcomes. We developed a risk score for predicting persistent CSA-AKI, the 'EPIS CSA-AKI r…
View article: Self-Reported Outcome of Living Kidney Donation Correlates With Perioperative Complications not With Surgical Techniques
Self-Reported Outcome of Living Kidney Donation Correlates With Perioperative Complications not With Surgical Techniques Open
Although the surgical technique does not directly affect donors' QoL shortly after donation, minimally invasive procedures result in shorter hospital stays and a quicker return to work. Self-reported complications have a greater impact on …
View article: Indocyanine green quantification in full robotic esophagectomy using an unsupervised learning approach
Indocyanine green quantification in full robotic esophagectomy using an unsupervised learning approach Open
An unsupervised learning approach to quantify intraoperative indocyanine green imaging could aid the prediction of anastomotic leakage after robotic-assisted minimally invasive esophagectomy in future treatments. However, the value of this…
View article: Hyperreflective material evolution patterns during long term anti-VEGF therapy in neovascular age-related macular degeneration
Hyperreflective material evolution patterns during long term anti-VEGF therapy in neovascular age-related macular degeneration Open
This retrospective, real-life cohort was analyzed to detect the frequency of different HRM evolution patterns and their correlation with MNV types, morphological and functional changes in exudative nAMD under long-term anti-VEGF therapy. W…
View article: Morphological changes of macular neovascularization during long-term anti-VEGF-therapy in neovascular age-related macular degeneration
Morphological changes of macular neovascularization during long-term anti-VEGF-therapy in neovascular age-related macular degeneration Open
Purpose To analyze the morphological changes of macular neovascularization (MNV) in exudative neovascular age-related macular degeneration under long-term intravitreal anti-vascular endothelial growth factor (VEGF) therapy in a retrospecti…
View article: Graft-versus-host disease following liver transplantation: A systematic review of literature
Graft-versus-host disease following liver transplantation: A systematic review of literature Open
Background: Graft-versus-host disease following liver transplantation is a serious and usually fatal complication. Data identifying the risk factors and specifying the diagnosis and treatment options of the disease are scarce and contentio…
View article: Submacular Hemorrhages Show No Significant Seasonal Variations in a European Cohort
Submacular Hemorrhages Show No Significant Seasonal Variations in a European Cohort Open
The aim of the article is to investigate the seasonality of acute submacular hemorrhages (SMHs) in a European population and analyze the influence of the seasons, arterial hypertension, and intake of anticoagulatory/antiplatelet (AC/AP) me…
View article: Immunodeficiency is prevalent in congenital heart disease and associated with increased risk of emergency admissions and death
Immunodeficiency is prevalent in congenital heart disease and associated with increased risk of emergency admissions and death Open
Aims To provide population-based data on the prevalence and clinical significance of immune deficiency syndromes (IDS) associated with congenital heart disease (CHD). Methods and results Utilizing administrative German Health System data t…
View article: Submacular Hemorrhages Show no Significant Seasonal Variations in a European Cohort
Submacular Hemorrhages Show no Significant Seasonal Variations in a European Cohort Open
Purpose: To investigate seasonal variations in the onset of acute submacular hemorrhages (SMHs) in a European population and analyze the influence of the seasons, arterial hypertension and intake of anticoagulatory/antiplatelet (AC/AP) med…
View article: How Old Is Old? An Age-Stratified Analysis of Elderly Liver Donors above 65
How Old Is Old? An Age-Stratified Analysis of Elderly Liver Donors above 65 Open
In liver transplantation, older donor age is a well-known risk factor for dismal outcomes, especially due to the high susceptibility of older grafts to ischemia-reperfusion injury. However, whether the factors correlating with impaired gra…
View article: Effect of Intraoperative Handovers of Anesthesia Care on Mortality, Readmission, or Postoperative Complications Among Adults
Effect of Intraoperative Handovers of Anesthesia Care on Mortality, Readmission, or Postoperative Complications Among Adults Open
ClinicalTrials.gov Identifier: NCT04016454.
View article: Simplifying Diagnosis of Fetal Alcohol Syndrome Using Machine Learning Methods
Simplifying Diagnosis of Fetal Alcohol Syndrome Using Machine Learning Methods Open
Introduction The fetal alcohol spectrum disorder (FASD) is a complex and heterogeneous disorder, caused by gestational exposure to alcohol. Patients with fetal alcohol syndrome (FAS—most severe form of FASD) show abnormal facial features. …
View article: Risk of tumor recurrence in intracranial meningiomas: comparative analyses of the predictive value of the postoperative tumor volume and the Simpson classification
Risk of tumor recurrence in intracranial meningiomas: comparative analyses of the predictive value of the postoperative tumor volume and the Simpson classification Open
OBJECTIVE In meningiomas, the Simpson grading system is applied to estimate the risk of postoperative recurrence, but might suffer from bias and limited overview of the resection cavity. In contrast, the value of the postoperative tumor vo…
View article: First-In-Class CD13-Targeted Tissue Factor tTF-NGR in Patients with Recurrent or Refractory Malignant Tumors: Results of a Phase I Dose-Escalation Study
First-In-Class CD13-Targeted Tissue Factor tTF-NGR in Patients with Recurrent or Refractory Malignant Tumors: Results of a Phase I Dose-Escalation Study Open
Background: Aminopeptidase N (CD13) is present on tumor vasculature cells and some tumor cells. Truncated tissue factor (tTF) with a C-terminal NGR-peptide (tTF-NGR) binds to CD13 and causes tumor vascular thrombosis with infarction. Metho…
View article: Comparing Plasma Exchange to Escalated Methyl Prednisolone in Refractory Multiple Sclerosis Relapses
Comparing Plasma Exchange to Escalated Methyl Prednisolone in Refractory Multiple Sclerosis Relapses Open
Intravenous methyl prednisolone (IVMPS) represents the standard of care for multiple sclerosis (MS) relapses, but fail to improve symptoms in one quarter of patients. In this regard, apart from extending steroid treatment to a higher dose,…
View article: Impact of nighttime procedures on outcomes after liver transplantation
Impact of nighttime procedures on outcomes after liver transplantation Open
Our retrospective single center data derived from a German transplant center within the Eurotransplant region provides evidence that oLT is a safe procedure irrespective of the starting time. Our data demonstrate that compared to daytime s…
View article: Repeatability, reproducibility and agreement of foveal avascular zone measurements using three different optical coherence tomography angiography devices
Repeatability, reproducibility and agreement of foveal avascular zone measurements using three different optical coherence tomography angiography devices Open
Good reproducibility and repeatability were observed for all three devices. However, the agreement analysis revealed slight, but significant differences, which might limit alternating use of these devices for clinical research and follow-u…
View article: The weekend effect in liver transplantation
The weekend effect in liver transplantation Open
We provide the first data for the Eurotransplant region on oLT stratified for weekend and weekday procedures and our findings suggest there was no weekend effect on oLT. While we hypothesize that the absent weekend effect is due to standar…