Eimear Wallace
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View article: Mechanotherapy: Modulating immune cell function in tissue regeneration and fibrosis
Mechanotherapy: Modulating immune cell function in tissue regeneration and fibrosis Open
Mechanotherapy - therapy which uses mechanical forces to produce a remedial or prophylactic effect - has great potential to improve therapeutic outcomes in the fields of regenerative medicine and drug delivery due to its adaptable and tuna…
View article: Actuation‐Mediated Compression of a Mechanoresponsive Hydrogel by Soft Robotics to Control Release of Therapeutic Proteins
Actuation‐Mediated Compression of a Mechanoresponsive Hydrogel by Soft Robotics to Control Release of Therapeutic Proteins Open
Therapeutic proteins, the fastest growing class of pharmaceuticals, are subject to rapid proteolytic degradation in vivo, rendering them inactive. Sophisticated drug delivery systems that maintain protein stability, prolong therapeutic eff…
View article: Exploring therapy transport from implantable medical devices using experimentally informed computational methods
Exploring therapy transport from implantable medical devices using experimentally informed computational methods Open
An experimentally informed device model capturing reduced factor transport resulting from the fibrous capsule (FC) and recovered using fluid flow.
View article: Medical devices, smart drug delivery, wearables and technology for the treatment of Diabetes Mellitus
Medical devices, smart drug delivery, wearables and technology for the treatment of Diabetes Mellitus Open
Diabetes mellitus refers to a group of metabolic disorders which affect how the body uses glucose impacting approximately 9% of the population worldwide. This review covers the most recent technological advances envisioned to control and/o…
View article: Long QT Syndrome: Genetics and Future Perspective
Long QT Syndrome: Genetics and Future Perspective Open
Long QT syndrome (LQTS) is an inherited primary arrhythmia syndrome that may present with malignant arrhythmia and, rarely, risk of sudden death. The clinical symptoms include palpitations, syncope, and anoxic seizures secondary to ventric…
View article: SO018SERUM AND URINE SOLUBLE TNFR-1 AND TNFR-2 DIFFERENTIALLY CORRELATE WITH EGFR AND ALBUMINURIA IN DIABETIC KIDNEY DISEASE
SO018SERUM AND URINE SOLUBLE TNFR-1 AND TNFR-2 DIFFERENTIALLY CORRELATE WITH EGFR AND ALBUMINURIA IN DIABETIC KIDNEY DISEASE Open
features of DKD were selected as candidate biomarkers.A self-assembling PCR array consisting of mRNAs with largest fold changes(FC) was constructed for further evaluation.9 randomly-selected urinary mRNA samples of DKD patients were used t…