Eithne Downey
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View article: Survival Outcomes in Breast Cancer Patients With Metastatic Bone Disease
Survival Outcomes in Breast Cancer Patients With Metastatic Bone Disease Open
Objective To evaluate the survival outcomes of breast cancer patients with metastatic bone disease and to assess whether these patients exhibit different prognoses compared to those with more extensive metastatic involvement. Background Sy…
View article: Prognostic Significance of Delays in Initiation of Adjuvant Trastuzumab-Based Therapy in Patients with HER2-Positive Breast Cancer
Prognostic Significance of Delays in Initiation of Adjuvant Trastuzumab-Based Therapy in Patients with HER2-Positive Breast Cancer Open
Purpose: Adjuvant trastuzumab therapy has improved outcomes in HER2-positive breast cancer, but the impact of the timing of its initiation remains unclear. This study evaluates the effect of time to adjuvant trastuzumab-based therapy (TTAT…
View article: Wire-guided localisation vs HOLOGIC® LOCalizer™ radiofrequency identification (RFID) tag localisation of non-palpable breast lesions; a comparative analysis of ease of use and accuracy of localisation
Wire-guided localisation vs HOLOGIC® LOCalizer™ radiofrequency identification (RFID) tag localisation of non-palpable breast lesions; a comparative analysis of ease of use and accuracy of localisation Open
While associated with fewer positive margins, tag localisation did not significantly lower re-excision rates and was more likely to fail than wire-guided localisation. Further studies may elucidate its possible benefits in select patients.
View article: Does Sentinel Lymph Node Biopsy Influence Subsequent Management Decisions in Women With Breast Cancer ≥ 70 Years Old?
Does Sentinel Lymph Node Biopsy Influence Subsequent Management Decisions in Women With Breast Cancer ≥ 70 Years Old? Open
In this study, SLNB did not significantly influence subsequent management decisions in patients over 80 and should rarely be performed in this cohort. However, SLNB still had a role in patients aged 70-80 and should be used selectively in …
View article: AB026. SOH24AB_045. Knowledge of BRCA1/BRCA2 pathogenic variant status in a non-Ashkenazi Jewish cohort is important for survival
AB026. SOH24AB_045. Knowledge of BRCA1/BRCA2 pathogenic variant status in a non-Ashkenazi Jewish cohort is important for survival Open
Background: BRCA1/2 pathogenic variant carriers have a higher lifetime risk of developing breast cancer. Risk-management options include breast surveillance or bilateral prophylactic mastectomy (BPM). The aim of this study was to assess if…
View article: Monopolar diathermy <i>versus</i> a vessel-sealing device for reducing postoperative drain output after simple mastectomy: randomized clinical trial
Monopolar diathermy <i>versus</i> a vessel-sealing device for reducing postoperative drain output after simple mastectomy: randomized clinical trial Open
Background Electrosurgical devices are commonly used during mastectomy for simultaneous dissection and haemostasis, and can provide potential benefits regarding vessel and lymphatic ligation. The aim of this prospective RCT was to assess w…
View article: Assessing Mode of Recurrence in Breast Cancer to Identify an Optimised Follow-Up Pathway: 10-Year Institutional Review
Assessing Mode of Recurrence in Breast Cancer to Identify an Optimised Follow-Up Pathway: 10-Year Institutional Review Open
Background Breast cancer surveillance programmes ensure early identification of recurrence which maximises overall survival. Programmes include annual clinical examination and radiological assessment. There remains debate around the value …
View article: O078 Is there a role for SLNB in women with breast cancer &gt;70 years old? A retrospective institutional review
O078 Is there a role for SLNB in women with breast cancer >70 years old? A retrospective institutional review Open
Introduction The Choosing Wisely guidelines were published to de-escalate surgical staging of the axilla in women >70 years of age with early invasive breast cancer. They advised against performing a sentinel lymph node biopsy (SLNB) in…
View article: O079 Randomised controlled trial of LigaSure use versus monopolar diathermy in mastectomy
O079 Randomised controlled trial of LigaSure use versus monopolar diathermy in mastectomy Open
Introduction LigaSure is an electrothermal bipolar vessel-sealing system shown to decrease blood loss and drainage volume compared to electrocautery in axillary node dissection. This prospective randomised controlled trial aimed to assess …
View article: O081 De-escalating axillary dissection in mastectomy cases for ductal carcinoma <i>in-situ</i>
O081 De-escalating axillary dissection in mastectomy cases for ductal carcinoma <i>in-situ</i> Open
Introduction Axillary surgery has been de-escalated in invasive breast carcinoma and may be omitted in certain age groups according to the Choosing Wisely initiative. Invasion can be found in 10-20% of patients with ductal carcinoma in-sit…
View article: O61: TEXTBOOK SURGICAL OUTCOMES IN OESOPHAGO-GASTRIC CANCER: THE INFLUENCE OF NATIONAL KEY PERFORMANCE INDICATORS
O61: TEXTBOOK SURGICAL OUTCOMES IN OESOPHAGO-GASTRIC CANCER: THE INFLUENCE OF NATIONAL KEY PERFORMANCE INDICATORS Open
Introduction High quality surgery remains the cornerstone of treating oesophago-gastric malignancy. Recent work from the Dutch Upper-gastrointestinal Cancer Audit (DUCA) have defined ten surgical and perioperative ‘textbook’ parameters tha…
View article: O30: EVALUATION OF AXILLARY LYMPH NODE METASTATIC BURDEN BY PREOPERATIVE ULTRASOUND
O30: EVALUATION OF AXILLARY LYMPH NODE METASTATIC BURDEN BY PREOPERATIVE ULTRASOUND Open
Introduction Sentinel lymph node biopsy (SLNB) is the gold standard for determining axillary nodal status. There is growing interest in using preoperative axillary ultrasound (AUS) as a non-invasive means of assessing the axilla. However, …
View article: AB030. Assessing axillary nodal burden using preoperative axillary ultrasound
AB030. Assessing axillary nodal burden using preoperative axillary ultrasound Open
Background: Sentinel lymph node biopsy (SLNB) is the gold standard for determining axillary nodal status. There is growing interest in using preoperative axillary ultrasound (AUS) as a non-invasive means of assessing the axilla. However, A…
View article: AB098. Textbook surgical outcomes in oesophageal cancer: the influence of national key performance indicators
AB098. Textbook surgical outcomes in oesophageal cancer: the influence of national key performance indicators Open
Background: High quality surgery remains the cornerstone of treating oesophageal malignancy. Recent work from the Dutch Upper-gastrointestinal Cancer Audit (DUCA) has defined ten surgical and perioperative ‘textbook’ parameters that correl…