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View article: Majejaitan Activity and High Serum BDNF Levels as Protective Factors Against Cognitive Impairment in the Elderly
Majejaitan Activity and High Serum BDNF Levels as Protective Factors Against Cognitive Impairment in the Elderly Open
The aging process in the elderly affects not only physical capabilities but also cognitive function. Cognitive impairment in older adults is thought to be associated with physical activity and neurotrophic factors, particularly the serum l…
View article: Serum Nerve Growth Factor Levels in Painful Diabetic Neuropathy: A Systematic Review and Meta-Analysis
Serum Nerve Growth Factor Levels in Painful Diabetic Neuropathy: A Systematic Review and Meta-Analysis Open
Background: Painful diabetic neuropathy (PDN) is a severe complication of type 2 diabetes mellitus (T2DM). Nerve Growth Factor (NGF) is vital for neuronal health, but its status as a systemic biomarker in PDN is contested due to conflictin…
View article: Weaving Activity and High Plasma Levels of Brain-Derived Neurothrophic Factor (BDNF) As A Protective Factors Against Cognitive Dysfunction in Middle-Aged Women
Weaving Activity and High Plasma Levels of Brain-Derived Neurothrophic Factor (BDNF) As A Protective Factors Against Cognitive Dysfunction in Middle-Aged Women Open
Cognitive dysfunction is a common problem associated with ageing and affects quality of life. As a repetitive activity, weaving and brain-derived neurotrophic factor (BDNF) levels are believed to be essential in maintaining cognitive funct…
View article: DEVELOPING NEW ICH (nICH) AND ICH-SURGICAL EVACUATION (ICH-SE) SCORE FOR PREDICTING 30-DAY MORTALITY OF SPONTANEOUS INTRACEREBRAL HEMORRHAGE
DEVELOPING NEW ICH (nICH) AND ICH-SURGICAL EVACUATION (ICH-SE) SCORE FOR PREDICTING 30-DAY MORTALITY OF SPONTANEOUS INTRACEREBRAL HEMORRHAGE Open
Introduction: The Original Intracerebral Hemorrhage (oICH) score has been widely used as a clinical assessment scale that is consistent and reliable for predicting patient mortality. However, the ICH score is sometimes complicated, does no…
View article: Serum matrix metalloproteases-2 and chemokine ligand-2 levels in patients with painful diabetic neuropathy
Serum matrix metalloproteases-2 and chemokine ligand-2 levels in patients with painful diabetic neuropathy Open
Background and objectives. Diabetic neuropathy is a prevalent complication in individuals with type 2 diabetes mellitus (DM). Recent studies indicate that the onset of neuropathic pain in both early and late stages necessitates matrix meta…
View article: The Role of Dry Needling in Complex Regional Pain Syndrome Management: A Mini Review
The Role of Dry Needling in Complex Regional Pain Syndrome Management: A Mini Review Open
Complex Regional Pain Syndrome (CRPS) presents as a multifaceted condition characterized by pain, autonomic dysregulation, and motor dysfunction. Within the realm of pain management, Dry Needling (DN) emerges as a promising therapeutic mod…
View article: Low Serum Folic Acid Levels As A Risk Factor for Cognitive Function Impairment in the Elderly at Community Health Centre in South Denpasar
Low Serum Folic Acid Levels As A Risk Factor for Cognitive Function Impairment in the Elderly at Community Health Centre in South Denpasar Open
Background: Aging is often associated with progressive loss of function in various systems, including cognitive function. Impairment Cognitive Function (ICF) is thought to be associated with low folic acid levels in the blood, which is oft…
View article: Biomarker Mild Cognitive Impairment in Older Adults: A Review
Biomarker Mild Cognitive Impairment in Older Adults: A Review Open
Dementia and other neurodegenerative diseases are on the rise due to an ageing population; moderate cognitive impairment (MCI) is a precursor to the more serious illness. Measurable cognitive impairments that do not meet the dementia diagn…
View article: Menopause and Risk of Cognitive Impairment - A Literature Review
Menopause and Risk of Cognitive Impairment - A Literature Review Open
he World Health Organization (WHO) defines menopause as the permanent cessation of menstruation due to a decrease in ovarian activity without physiological or pathological causes. Twelve months of amenorrhea signal menopause. Menopause usu…
View article: Proportion of Poor Sleep Quality and Sleep Hygiene Implementation in Medical Students of Udayana University
Proportion of Poor Sleep Quality and Sleep Hygiene Implementation in Medical Students of Udayana University Open
Background: A good night's sleep is sleep with a sufficient duration, namely seven to eight hours a day. Sleep quality can be determined by sleep hygiene. People who practice sleep hygiene have better energy and cognitive function. Poor sl…
View article: Unveiling the Risk Factors for Postoperative Cognitive Dysfunction
Unveiling the Risk Factors for Postoperative Cognitive Dysfunction Open
Postoperative cognitive decline (POCD), a concerning consequence of surgery, can significantly impact a patient's recovery and long-term well-being. This study gives insights into a multifaceted exploration of risk factors associated with …
View article: Coenzyme Q10 As A Risk Factor for Myofascial Pain Syndrome in Post-Ischemic Stroke Patients: A Literature Review
Coenzyme Q10 As A Risk Factor for Myofascial Pain Syndrome in Post-Ischemic Stroke Patients: A Literature Review Open
Stroke remains a leading cause of long-term disability worldwide, with 85% of cases classified as ischemic due to arterial blockage and resulting neuronal injury. Among post-stroke complications, musculoskeletal disorders significantly imp…
View article: The Role of Phosphorylated-Tau 181 in Enhancing Neuroplasticity After Ischemic Stroke
The Role of Phosphorylated-Tau 181 in Enhancing Neuroplasticity After Ischemic Stroke Open
Ischemic stroke is a predominant cause of neurological impairment globally. Notwithstanding progress in acute treatment, the long-term functional recovery of individuals continues to be constrained. Recent research has concentrated on the …
View article: Neurofilament Light Chain (NfL) as A Potential Biomarker of Chemotherapy-Induced Peripheral Neuropathy (CIPN) in Cervical Cancer Patients
Neurofilament Light Chain (NfL) as A Potential Biomarker of Chemotherapy-Induced Peripheral Neuropathy (CIPN) in Cervical Cancer Patients Open
Chemotherapy-Induced Peripheral Neuropathy (CIPN) is a complication of chemotherapy observed in several types of cancer, including cervical cancer. The pathomechanism of CIPN is multifactorial and depends on the type and dosage of chemothe…
View article: THE CORRELATION OF SLEEP QUALITY AND SHORT-TERM MEMORY FUNCTION IN MEDICAL STUDENTS
THE CORRELATION OF SLEEP QUALITY AND SHORT-TERM MEMORY FUNCTION IN MEDICAL STUDENTS Open
Background: Study on the correlation of sleep quality with short-term memory function in medical students has a high urgency considering that intelligence and good memory function are essential for their performance and learning ability in…
View article: High Serum Levels of Transforming Growth Factor β1 (TGF-β1) a Risk Factor for Neuropathic Pain in Patients with Multibacillary Leprosy
High Serum Levels of Transforming Growth Factor β1 (TGF-β1) a Risk Factor for Neuropathic Pain in Patients with Multibacillary Leprosy Open
Leprosy caused by Mycobacterium leprae is a chronic infectious disease, affecting the peripheral nerves, skin, and other organs. Neuropathic pain is a common complication, occurring in approximately 15% of leprosy patients, even after trea…
View article: Brain-Derived Neurotrophic Factor (BDNF) pada pasien Human Immunodeficiency Virus (HIV) dengan nyeri neuropatik
Brain-Derived Neurotrophic Factor (BDNF) pada pasien Human Immunodeficiency Virus (HIV) dengan nyeri neuropatik Open
Introduction: Problems related to Human Immunodeficiency Virus (HIV) infection have become a global concern as an infectious disease that infected 36.9 million patients in 2015. Neuropathic pain is one of the neurological complications tha…
View article: The Role of Oxytocin in Maintaining Sleep Quality of Leprosy Patient: A Literature Review
The Role of Oxytocin in Maintaining Sleep Quality of Leprosy Patient: A Literature Review Open
Around 80% of leprosy sufferers complain of pain that affects sleep quality and mental health, which has an impact on insomnia. Several factors impair the quality of life in leprosy, including skin lesions and social stigma, long treatment…
View article: Chronic Back Pain as a Clinical Manifestation of Myofascial Pain Syndrome
Chronic Back Pain as a Clinical Manifestation of Myofascial Pain Syndrome Open
Introduction: Myofascial pain syndrome (MPS) is a condition of muscle or fascial pain, acute or chronic, involving sensory, motor or autonomic function, which is associated with myofascial trigger points (TrP). The pain caused by TrP can c…
View article: CCL-2 as a Potential Biomarker for Neuropathic Pain in Leprosy: A Literature Review
CCL-2 as a Potential Biomarker for Neuropathic Pain in Leprosy: A Literature Review Open
Neuropathic pain is a debilitating symptom in leprosy patients that significantly impacts their quality of life. While the mechanisms underlying this pain remain unclear, recent research suggests a potential role for C-C motif chemokine li…
View article: Global Insights on Prehospital Stroke Care: A Comprehensive Review of Challenges and Solutions in Low- and Middle-Income Countries
Global Insights on Prehospital Stroke Care: A Comprehensive Review of Challenges and Solutions in Low- and Middle-Income Countries Open
Stroke is a leading cause of disability and mortality worldwide, and it disproportionately affects low- and middle-income countries (LMICs), which account for 88% of stroke fatalities. Prehospital stroke care delays are a crucial obstacle …
View article: Chemotherapy-induced peripheral neuropathy biomarkers: current updates, challenges, and potentials
Chemotherapy-induced peripheral neuropathy biomarkers: current updates, challenges, and potentials Open
Chemotherapy-induced peripheral neuropathy (CIPN) is a debilitating condition of peripheral nerve because of chemotherapeutic agent exposure among cancer patients. Despite its relatively high prevalence, to date, there has been no specific…
View article: Vitamin D Deficiency as a Factor Associated with Neuropathic Pain in Multibacillary Type Morbus Hansen
Vitamin D Deficiency as a Factor Associated with Neuropathic Pain in Multibacillary Type Morbus Hansen Open
Objective: Morbus Hansen (MH), caused by Mycobacterium leprae, is marked by neuropathic pain. Prior studies link low vitamin D levels to diabetic neuropathic pain, yet research on its role in MH-related neuropathic pain is limited. This st…
View article: THE EFFECT OF DRY NEEDLING THERAPY ON MYOFASCIAL PAIN SYNDROME
THE EFFECT OF DRY NEEDLING THERAPY ON MYOFASCIAL PAIN SYNDROME Open
Background: One of the nonpharmacological management that can currently be used to treat Myofascial Pain Syndrome (MPS) is dry needling (DN). Dry needling is a pain intervention technique by inserting a solid needle into the skin to stimul…
View article: EVALUATION OF VITAMIN B12 LEVELS WITH NEUROPATHIC PAIN IN HEMODIALYSIS PATIENTS: A SINGLE CENTER OBSERVATIONAL STUDY
EVALUATION OF VITAMIN B12 LEVELS WITH NEUROPATHIC PAIN IN HEMODIALYSIS PATIENTS: A SINGLE CENTER OBSERVATIONAL STUDY Open
Background: Uremic syndrome in chronic kidney disease (CKD), particularly in hemodialysis (HD) patients, is a growing global health problem. The majority of patients with this condition experience one or more neurological disorders, such a…
View article: Comorbidities, social, and psychological factors associated with headache in adult Indonesians: data from the 5th Indonesian Family Life Survey (IFLS-5)
Comorbidities, social, and psychological factors associated with headache in adult Indonesians: data from the 5th Indonesian Family Life Survey (IFLS-5) Open
BackgroundHeadache is a significant health problem worldwide, but national data on headaches in Indonesia are unavailable. Various risk factors have been identified as triggers or factors affecting its occurrence and severity. This study a…
View article: Astrocyte dysregulation as an epileptogenic factor: a systematic review
Astrocyte dysregulation as an epileptogenic factor: a systematic review Open
Background Epilepsy initiation involves multifactorial etiologies, including genetic susceptibility, structural anomalies, and glial cell dysregulations, particularly in astrocytes. Despite advancements in understanding various factors, th…
View article: Effect of botulinum toxin A on tyrosinase and melanin: A literature review
Effect of botulinum toxin A on tyrosinase and melanin: A literature review Open
Background: Melanogenesis is the process of forming melanin pigment initiated by the amino acid L-tyrosine; the main enzyme is tyrosinase. Tyrosinase acts as a catalyst for the hydroxylation reaction of L-tyrosine to L-DOPA and the oxidati…