Ekaterina Gushchanskaia
YOU?
Author Swipe
View article: DOT1L stimulates MYC/Mondo transcription factor activity by promoting its degradation cycle on chromatin
DOT1L stimulates MYC/Mondo transcription factor activity by promoting its degradation cycle on chromatin Open
SUMMARY The proto-oncogene c-MYC is a key representative of the MYC transcription factor network regulating growth and metabolism. MML-1 (Myc- and Mondo-like) is its homolog in C. elegans . The functional and molecular cooperation between …
View article: DOT1L complex suppresses transcription from enhancer elements and ectopic RNAi in <i>Caenorhabditis elegans</i>
DOT1L complex suppresses transcription from enhancer elements and ectopic RNAi in <i>Caenorhabditis elegans</i> Open
Methylation of histone H3 on lysine 79 (H3K79) by DOT1L is associated with actively transcribed genes. Earlier, we described that DOT-1.1, the Caenorhabditis elegans homolog of mammalian DOT1L, cooperates with the chromatin-binding protein…
View article: Interplay between small RNA pathways shapes chromatin landscapes in C. elegans
Interplay between small RNA pathways shapes chromatin landscapes in C. elegans Open
The nematode Caenorhabditis elegans contains several types of endogenous small interfering RNAs (endo-siRNAs) produced by RNA-dependent RNA polymerase (RdRP) complexes. Both ‘silencing’ siRNAs bound by Worm-specific Argonautes (WAGO) and ‘…
View article: DOT1L suppresses nuclear RNAi originating from enhancer elements in <i>Caenorhabditis elegans</i>
DOT1L suppresses nuclear RNAi originating from enhancer elements in <i>Caenorhabditis elegans</i> Open
Methylation of histone H3 on lysine 79 (H3K79) by DOT1L is associated with actively transcribed genes. Earlier, we described that DOT-1.1, the Caenorhabditis elegans DOT1L homologue, cooperates with the chromatin-binding protein ZFP-1 (AF1…
View article: The interplay between small RNA pathways shapes chromatin landscapes in<i>C. elegans</i>
The interplay between small RNA pathways shapes chromatin landscapes in<i>C. elegans</i> Open
The nematode C. elegans contains several types of endogenous small interfering RNAs (endo-siRNAs) produced by RNA-dependent RNA polymerase (RdRP) complexes. Both “silencing” siRNAs bound by Worm-specific Argonautes (WAGO) and “activating” …