Ekawat Vichayanrat
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View article: Cardiovascular autonomic failure correlates with cutaneous autonomic denervation in PD and MSA
Cardiovascular autonomic failure correlates with cutaneous autonomic denervation in PD and MSA Open
Purpose Cardiovascular autonomic failure and neurogenic orthostatic hypotension (nOH) are common and disabling in Parkinson’s disease (PD) and multiple system atrophy (MSA). Recent studies have shown evidence of postganglionic autonomic de…
View article: Multimodal Autonomic Biomarkers Predict Phenoconversion in Pure Autonomic Failure
Multimodal Autonomic Biomarkers Predict Phenoconversion in Pure Autonomic Failure Open
Background Pure autonomic failure (PAF) presents with autonomic failure without other neurological features. A third develop central neurological features, fulfilling criteria for multiple system atrophy (MSA) and Lewy body diseases (LBD),…
View article: Pure autonomic failure: a natural history study of the Queen Square cohort
Pure autonomic failure: a natural history study of the Queen Square cohort Open
The current research challenge in pure autonomic failure (PAF) lies in identifying specific biomarkers that can differentiate it from the other Lewy body disorders (Parkinson’s disease, Parkinson’s disease dementia, dementia with Lewy bodi…
View article: Pelvic autonomic dysfunction is common in patients with pure autonomic failure
Pelvic autonomic dysfunction is common in patients with pure autonomic failure Open
Background and Purpose Pure autonomic failure (PAF) presents primarily as cardiovascular autonomic failure and may phenoconvert to other neurodegenerative disorders. However, the involvement of other autonomic functions has been poorly eva…
View article: Cardiovascular autonomic failure correlates with cutaneous autonomic devervation in PD and MSA
Cardiovascular autonomic failure correlates with cutaneous autonomic devervation in PD and MSA Open
Background Cardiovascular autonomic failure and neurogenic orthostatic hypotension (nOH) are common and disabling in Parkinson’s disease (PD) and multiple system atrophy (MSA). Recent studies have shown evidence of postganglionic denervati…
View article: Cardiovascular autonomic failure in hereditary transthyretin amyloidosis and TTR carriers is an early and progressive disease marker
Cardiovascular autonomic failure in hereditary transthyretin amyloidosis and TTR carriers is an early and progressive disease marker Open
Background. The cardiomyopathic and neuropathic phenotype of hereditary transthyretin amyloidosis are well recognized. Cardiovascular autonomic dysfunction is less systematically and objectively assessed. Methods. Autonomic and clinical fe…
View article: Abnormal dopamine transporter imaging in pure autonomic failure: a potential biomarker of central nervous system involvement
Abnormal dopamine transporter imaging in pure autonomic failure: a potential biomarker of central nervous system involvement Open
Background and purpose Pure autonomic failure (PAF) is a rare progressive neurodegenerative disease characterized by neurogenic orthostatic hypotension at presentation, without other neurological abnormalities. Some patients may develop ot…
View article: Diagnosing Premotor Multiple System Atrophy
Diagnosing Premotor Multiple System Atrophy Open
Almost one-third of patients with MSA presented with nonmotor features, which could predate motor symptoms by up to 6 years. Cardiovascular autonomic failure and early urinary catheterization were predictors of poorer outcomes. A normal su…
View article: 246 NOCTURNAL POLYURIA IS COMMON IN PATIENTS WITH PURE AUTONOMIC FAILURE
246 NOCTURNAL POLYURIA IS COMMON IN PATIENTS WITH PURE AUTONOMIC FAILURE Open
View article: Autonomic dysfunction after moderate-to-severe traumatic brain injury: symptom spectrum and clinical testing outcomes
Autonomic dysfunction after moderate-to-severe traumatic brain injury: symptom spectrum and clinical testing outcomes Open
Background Survivors of moderate-to-severe traumatic brain injury (msTBI) frequently experience troublesome unexplained somatic symptoms. Autonomic dysfunction may contribute to these symptoms. However, there is no previous study of clinic…
View article: Postganglionic Sudomotor Assessment in Early Stage of Multiple System Atrophy and Parkinson Disease
Postganglionic Sudomotor Assessment in Early Stage of Multiple System Atrophy and Parkinson Disease Open
This study provides Class II evidence that postganglionic sudomotor morpho-functional assessment accurately distinguish patients with PD from patients with MSA-P.
View article: Autonomic dysfunction after moderate-severe traumatic brain injury: symptom spectrum and clinical testing outcomes
Autonomic dysfunction after moderate-severe traumatic brain injury: symptom spectrum and clinical testing outcomes Open
Background and Objective Survivors of moderate-severe traumatic brain injury (msTBI) frequently experience chronic, debilitating somatic symptoms, which are largely unexplained. The phenomenon of paroxysmal sympathetic hyperactivity, refle…
View article: An update on MSA: premotor and non-motor features open a window of opportunities for early diagnosis and intervention
An update on MSA: premotor and non-motor features open a window of opportunities for early diagnosis and intervention Open
View article: Autonomic dysfunction in genetic forms of synucleinopathies
Autonomic dysfunction in genetic forms of synucleinopathies Open
The discovery of genetic links between alpha‐synuclein and PD has opened unprecedented opportunities for research into a new group of diseases, now collectively known as synucleinopathies. Autonomic dysfunction, including cardiac sympathet…
View article: Twenty‐four‐hour ambulatory blood pressure and heart rate profiles in diagnosing orthostatic hypotension in Parkinson's disease and multiple system atrophy
Twenty‐four‐hour ambulatory blood pressure and heart rate profiles in diagnosing orthostatic hypotension in Parkinson's disease and multiple system atrophy Open
Background and purpose Twenty‐four‐hour ambulatory blood pressure and heart rate monitoring (24‐h ABPM ) can provide vital information on circadian blood pressure ( BP ) profiles, which are commonly abnormal in Parkinson's disease with and…
View article: Non-dipping nocturnal blood pressure and psychosis parameters in Parkinson disease
Non-dipping nocturnal blood pressure and psychosis parameters in Parkinson disease Open