Elaine M. Urbina
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View article: Collecting at-Home Biometric Measures for Longitudinal Research From the i3C: Feasibility and Acceptability Study
Collecting at-Home Biometric Measures for Longitudinal Research From the i3C: Feasibility and Acceptability Study Open
Background The use of individual wearable devices or internet-based applications to collect biometric data from research participants is popular, but several devices may be needed to replace a full set of research measurements. Objective I…
View article: A Multi-Omics Approach to Defining the Target Organ Injury in Youth with Primary Hypertension
A Multi-Omics Approach to Defining the Target Organ Injury in Youth with Primary Hypertension Open
View article: The association of childhood HDL cholesterol with atherosclerotic cardiovascular disease events in adults: findings from the International Childhood Cardiovascular Cohort Consortium
The association of childhood HDL cholesterol with atherosclerotic cardiovascular disease events in adults: findings from the International Childhood Cardiovascular Cohort Consortium Open
Aims The role of adult HDL-C in atherosclerotic cardiovascular disease (ASCVD) faces challenges from Mendelian randomizations and drug trials. However, the association between childhood HDL-C and its changes and adult ASCVD remains undefin…
View article: Hypertension, Obesity, and Target Organ Injury in Children: An Emerging Health Care Crisis
Hypertension, Obesity, and Target Organ Injury in Children: An Emerging Health Care Crisis Open
View article: Arterial Stiffness is Related to Diabetes-Associated Microvascular Complications: the SEARCH for Diabetes in Youth Study
Arterial Stiffness is Related to Diabetes-Associated Microvascular Complications: the SEARCH for Diabetes in Youth Study Open
Objective: To assess the relationship between arterial stiffness, an early marker of macrovascular cardiovascular disease, and microvascular complications in adolescents and young adults with youth-onset diabetes. Research Design and Metho…
View article: Contribution of Body Composition Measures to the Increased Left Ventricular Mass Index in Young Adult Black and White Females
Contribution of Body Composition Measures to the Increased Left Ventricular Mass Index in Young Adult Black and White Females Open
Objective: We aimed to determine the contribution of various types of body composition measures to the increased left ventricular mass index (LVMI) in young adult females. Methods: Data from the National Growth and Health Study (NGHS), inc…
View article: Predictors in Youth of Adult Cardiovascular Events
Predictors in Youth of Adult Cardiovascular Events Open
BACKGROUND AND OBJECTIVES Childhood risk factors are associated with cardiovascular events in adulthood. We compared the utility of a risk model based solely on nonlaboratory risk factors in adolescence versus a model that additionally inc…
View article: A Randomized Controlled Trial Comparing Loss versus Gain Incentives to Improve Adherence to an Obesity Treatment Intervention in Adolescents
A Randomized Controlled Trial Comparing Loss versus Gain Incentives to Improve Adherence to an Obesity Treatment Intervention in Adolescents Open
Background/Objectives: Adherence to pediatric obesity treatment can be challenging. Monetary incentives improve adherence to lifestyle interventions, with incentives framed as loss often more effective than those framed as gain. The object…
View article: A Clinical Tool to Relate Youth Risk Factors to Adult Cardiovascular Events and Type 2 Diabetes: The International Childhood Cardiovascular Cohort Consortium
A Clinical Tool to Relate Youth Risk Factors to Adult Cardiovascular Events and Type 2 Diabetes: The International Childhood Cardiovascular Cohort Consortium Open
View article: Abnormal Blood Pressure Among Individuals Evaluated for Latent Tuberculosis Infection in a U.S. Public Health Tuberculosis Clinic
Abnormal Blood Pressure Among Individuals Evaluated for Latent Tuberculosis Infection in a U.S. Public Health Tuberculosis Clinic Open
Summary Tuberculosis infection (LTBI) has been associated with increased cardiovascular risks. We aimed to characterize abnormal blood pressure (BP) readings in individuals with LTBI. We conducted a retrospective study of adults with LTBI …
View article: Cardiovascular Risk Factors in Childhood and Adulthood and Cardiovascular Disease in Middle Age
Cardiovascular Risk Factors in Childhood and Adulthood and Cardiovascular Disease in Middle Age Open
Importance Recent evidence suggests that childhood levels of serum lipids, blood pressure, body mass index (BMI), and smoking contribute to adult risk of cardiovascular disease (CVD). Evidence is lacking on whether this is independent of a…
View article: A Multi-Omics Approach to Defining Target Organ Injury in Youth with Primary Hypertension
A Multi-Omics Approach to Defining Target Organ Injury in Youth with Primary Hypertension Open
BACKGROUND Primary hypertension in childhood tracks into adulthood and may be associated with increased cardiovascular risk. Studies conducted in children and adolescents provide an opportunity to explore the early cardiovascular target or…
View article: Pediatric Blood Pressure and Cardiovascular Health in Adulthood
Pediatric Blood Pressure and Cardiovascular Health in Adulthood Open
View article: Personalized Intervention Based on Early Detection of Atherosclerosis
Personalized Intervention Based on Early Detection of Atherosclerosis Open
View article: Non–High-Density Lipoprotein Cholesterol Levels From Childhood to Adulthood and Cardiovascular Disease Events
Non–High-Density Lipoprotein Cholesterol Levels From Childhood to Adulthood and Cardiovascular Disease Events Open
Importance Elevated non–high-density lipoprotein cholesterol (non–HDL-C; a recommended measure of lipid-related cardiovascular risk) is common in children and increases risk of adult cardiovascular disease (CVD). Whether resolution of elev…
View article: Ambulatory Blood Pressure and Number of Subclinical Target Organ Injury Markers in Youth: The SHIP AHOY Study
Ambulatory Blood Pressure and Number of Subclinical Target Organ Injury Markers in Youth: The SHIP AHOY Study Open
Background Hypertension in adolescence is associated with subclinical target organ injury (TOI). We aimed to determine whether different blood pressure (BP) thresholds were associated with increasing number of TOI markers in healthy adoles…
View article: Tuberculosis infection and hypertension: prevalence estimates from the US National Health and Nutrition Examination Survey
Tuberculosis infection and hypertension: prevalence estimates from the US National Health and Nutrition Examination Survey Open
Objectives Tuberculosis infection (TBI) is marked by dynamic host–pathogen interactions with persistent low-grade inflammation and is associated with increased risk of cardiovascular diseases (CVD) including acute coronary syndrome, myocar…
View article: Use of lipid ratios to predict vascular target organ damage in youth
Use of lipid ratios to predict vascular target organ damage in youth Open
View article: 891 Maternal risk factor clusters and risk of infant congenital heart disease and maternal morbidity
891 Maternal risk factor clusters and risk of infant congenital heart disease and maternal morbidity Open
View article: Abnormal blood pressure among individuals evaluated for tuberculosis infection in a U.S. public health tuberculosis clinic
Abnormal blood pressure among individuals evaluated for tuberculosis infection in a U.S. public health tuberculosis clinic Open
Tuberculosis infection (TBI) has been associated with increased cardiovascular risks. We aimed to characterize abnormal blood pressure (BP) readings in individuals with TBI. We conducted a retrospective study of adults with TBI presenting …
View article: 2024 Recommendations for Validation of Noninvasive Arterial Pulse Wave Velocity Measurement Devices
2024 Recommendations for Validation of Noninvasive Arterial Pulse Wave Velocity Measurement Devices Open
BACKGROUND: Arterial stiffness, as measured by arterial pulse wave velocity (PWV), is an established biomarker for cardiovascular risk and target-organ damage in individuals with hypertension. With the emergence of new devices for assessin…
View article: Uric Acid Is Not Associated With Cardiovascular Health in Youth With Type 1 Diabetes: SEARCH for Diabetes in Youth Study
Uric Acid Is Not Associated With Cardiovascular Health in Youth With Type 1 Diabetes: SEARCH for Diabetes in Youth Study Open
Context Uric acid's role in cardiovascular health in youth with type 1 diabetes is unknown. Objective Investigate whether higher uric acid is associated with increased blood pressure (BP) and arterial stiffness over time in adolescents and…
View article: Poor Accuracy of Triage Blood Pressure Measurements in a Pediatric Obesity Hypertension Clinic
Poor Accuracy of Triage Blood Pressure Measurements in a Pediatric Obesity Hypertension Clinic Open
Accurate triage blood pressure (BP) measurements are essential for clinical decision making. We investigated the agreement and diagnostic accuracy of usual triage vs. standardized BP measurements in an obesity-related hypertension clinic. …
View article: RACIAL DIFFERENCES IN CARDIOVASCULAR RISK FACTORS AND THE DEVELOPMENT OF LEFT VENTRICULAR HYPERTROPHY
RACIAL DIFFERENCES IN CARDIOVASCULAR RISK FACTORS AND THE DEVELOPMENT OF LEFT VENTRICULAR HYPERTROPHY Open
Therapeutic Area: ASCVD/CVD Risk Factors Background: Obesity-related cardiovascular (CV) risk factors are associated with increased left ventricular mass, a risk factor for adult CV disease. Whether there are race differences in this relat…
View article: Blood Pressure in Children in the 21st Century: What Do We Know and Where Do We Go From Here?
Blood Pressure in Children in the 21st Century: What Do We Know and Where Do We Go From Here? Open
The association between hypertension in adulthood and cardiovascular morbidity and death is well known. Based on that association, a diagnosis of elevated blood pressure in children has been clinically interpreted as early cardiovascular d…
View article: Tuberculosis infection and hypertension: Prevalence estimates from the US National Health and Nutrition Examination Survey
Tuberculosis infection and hypertension: Prevalence estimates from the US National Health and Nutrition Examination Survey Open
Objectives Latent Tuberculosis infection (LTBI) is marked by dynamic host-pathogen interactions with persistent low-grade inflammation and is associated with increased risk of cardiovascular diseases (CVD) including acute coronary syndrome…
View article: Diabetes Complications and Cognitive Function in Young Adults with Youth-Onset Type 1 or Type 2 Diabetes: The SEARCH for Diabetes in Youth Study
Diabetes Complications and Cognitive Function in Young Adults with Youth-Onset Type 1 or Type 2 Diabetes: The SEARCH for Diabetes in Youth Study Open
Aims/Hypotheses. People with type 1 (T1D) or type 2 diabetes (T2D) who also have diabetes complications can have pronounced cognitive deficits. It remains unknown, however, whether and how multiple diabetes complications co-occur with cogn…
View article: Exploring Racial and Ethnic Differences in Arterial Stiffness Among Youth and Young Adults With Type 1 Diabetes
Exploring Racial and Ethnic Differences in Arterial Stiffness Among Youth and Young Adults With Type 1 Diabetes Open
Background We examined arterial stiffness in individuals with type 1 diabetes, and explored whether differences between Hispanic, non‐Hispanic Black (NHB), and non‐Hispanic White (NHW) individuals were attributable to modifiable clinical a…
View article: Pediatric Primary Hypertension: An Underrecognized Condition: A Scientific Statement From the American Heart Association
Pediatric Primary Hypertension: An Underrecognized Condition: A Scientific Statement From the American Heart Association Open
The overall prevalence of hypertension in childhood is 2% to 5%, and the leading type of childhood hypertension is primary hypertension, especially in adolescence. As in adults, the leading risk factors for children with primary hypertensi…
View article: Association of Elevated Arterial Stiffness with Cardiac Target Organ Damage and Cardiac Autonomic Neuropathy in Young Adults with Diabetes: The SEARCH for Diabetes in Youth Study
Association of Elevated Arterial Stiffness with Cardiac Target Organ Damage and Cardiac Autonomic Neuropathy in Young Adults with Diabetes: The SEARCH for Diabetes in Youth Study Open
Background: Adults with diabetes are at risk of cardiovascular (CV) events, possibly due to increased arterial stiffness (AS) and cardiac autonomic neuropathy (CAN). We sought to determine if 1) AS is associated with cardiac tar…