Eleanor Hyde
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View article: ‘dstidyverse’: An Implementation of TidyverseWithin the DataSHIELD Ecosystem
‘dstidyverse’: An Implementation of TidyverseWithin the DataSHIELD Ecosystem Open
Background DataSHIELD is a mature, R-based federated learning platform that enables multi-site analysis without sharing individual participant data. While DataSHIELD includes many packages for data analysis, it lacks user-friendly data ma…
View article: dsTidyverse: An implementation of Tidyverse within the DataSHIELD ecosystem
dsTidyverse: An implementation of Tidyverse within the DataSHIELD ecosystem Open
This paper introduces dsTidyverse, an R package designed to enhance data handling within the federated analysis platform DataSHIELD. DataSHIELD enables multi-site analysis without direct data sharing, crucial for privacy-sensitive research…
View article: DataSHIELD: mitigating disclosure risk in a multi-site federated analysis platform
DataSHIELD: mitigating disclosure risk in a multi-site federated analysis platform Open
Motivation The validity of epidemiologic findings can be increased using triangulation, i.e. comparison of findings across contexts, and by having sufficiently large amounts of relevant data to analyse. However, access to data is often con…
View article: MOLGENIS Armadillo: a lightweight server for federated analysis using DataSHIELD
MOLGENIS Armadillo: a lightweight server for federated analysis using DataSHIELD Open
Summary Extensive human health data from cohort studies, national registries, and biobanks can reveal lifecourse risk factors impacting health. Combining these sources offers increased statistical power, rare outcome detection, replication…
View article: MOLGENIS Armadillo: a lightweight server for federated analysis using DataSHIELD
MOLGENIS Armadillo: a lightweight server for federated analysis using DataSHIELD Open
Summary. Extensive human health data from cohort studies, national registries, and biobanks can reveal lifecourse risk factors impacting health. Combining these sources offers increased statistical power, rare outcome detection, replicatio…
Social inequalities in child mental health trajectories: a longitudinal study using birth cohort data 12 countries Open
Background Social inequalities in child mental health are an important public health concern. Whilst previous studies have examined inequalities at a single time point, very few have used repeated measures outcome data to describe how thes…
View article: Metadata for Data dIscoverability aNd Study rEplicability in obseRVAtional Studies (MINERVA): Development and Pilot of a Metadata List and Catalogue in Europe
Metadata for Data dIscoverability aNd Study rEplicability in obseRVAtional Studies (MINERVA): Development and Pilot of a Metadata List and Catalogue in Europe Open
Purpose Metadata for data dIscoverability aNd study rEplicability in obseRVAtional studies (MINERVA), a European Medicines Agency–funded project (EUPAS39322), defined a set of metadata to describe real‐world data sources (RWDSs) and pilote…
Test report for FAIR data catalogue 2nd (D7.10) Open
The objective of this report is to summarise further user assessments of the second prototype of the ConcePTION FAIR data catalogue (see Deliverable 7.6 for description).
Towards an Interoperable Ecosystem of Research Cohort and Real-world Data Catalogues Enabling Multi-center Studies Open
Objectives: Existing individual-level human data cover large populations on many dimensions such as lifestyle, demography, laboratory measures, clinical parameters, etc. Recent years have seen large investments in data catalogues to FAIRif…
View article: LongITools:Dynamic longitudinal exposome trajectories in cardiovascular and metabolic noncommunicable diseases
LongITools:Dynamic longitudinal exposome trajectories in cardiovascular and metabolic noncommunicable diseases Open
The current epidemics of cardiovascular and metabolic noncommunicable diseases have emerged alongside dramatic modifications in lifestyle and living environments. These correspond to changes in our "modern" postwar societies globally chara…
View article: Advancing tools for human early lifecourse exposome research and translation (ATHLETE)
Advancing tools for human early lifecourse exposome research and translation (ATHLETE) Open
Early life stages are vulnerable to environmental hazards and present important windows of opportunity for lifelong disease prevention. This makes early life a relevant starting point for exposome studies. The Advancing Tools for Human Ear…
FAIRification of data: Great but how? Open
BACKGROUND AND AIM: The European Human Exposome Network (EHEN) unites 9 research projects studying the impact of environmental exposure on health, such as air quality, noise, chemicals, and urbanization. We report for the Metadata WG with …
Prototype of FAIR data catalogue - 2nd (D7.7) Open
This deliverable focuses on summarizing the delivery of the second prototype of the FAIR data catalogue for the ConcePTION project. Such prototype aims to collect summary level metadata on the CONCEPTION common data model and map this meta…
Test report for FAIR data catalogue (1st) (D7.9) Open
The purpose of this deliverable is to summarize initial user assessments of the first prototype of the ConcePTION FAIR data catalogue. This prototype focuses on the presentation of meta-data descriptions of population-based healthcare and …
The LifeCycle Project-EU Child Cohort Network: a federated analysis infrastructure and harmonized data of more than 250,000 children and parents Open
Early life is an important window of opportunity to improve health across the full lifecycle. An accumulating body of evidence suggests that exposure to adverse stressors during early life leads to developmental adaptations, which subseque…