Éléna Charpentier
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View article: Pneumocystis Infection in Pregnant Women: A Scoping Review
Pneumocystis Infection in Pregnant Women: A Scoping Review Open
Pneumocystis jirovecii is an opportunistic fungus that causes severe pneumonia in immunosuppressed individuals. While Pneumocystis colonization, a subclinical form of infection, has been studied in different populations, its implications d…
View article: Proteomic Approach to Study the Effect of Pneumocystis jirovecii Colonization in Idiopathic Pulmonary Fibrosis
Proteomic Approach to Study the Effect of Pneumocystis jirovecii Colonization in Idiopathic Pulmonary Fibrosis Open
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and interstitial disease with an unclear cause, believed to involve genetic, environmental, and molecular factors. Recent research suggested that Pneumocystis jirovecii (PJ) co…
View article: No evidence of pathogenicity of <i>Dientamoeba fragilis</i> following detection in stools: A case-control study
No evidence of pathogenicity of <i>Dientamoeba fragilis</i> following detection in stools: A case-control study Open
Dientamoeba fragilis is a ubiquitous intestinal parasite with detection in the stools that has become increasingly frequent following the advent of PCR as a routine screening tool. However, the pathogenicity of this parasite is still much …
View article: The gut-lung axis in the CFTR modulator era
The gut-lung axis in the CFTR modulator era Open
The advent of CFTR modulators represents a turning point in the history of cystic fibrosis (CF) management, changing profoundly the disease’s clinical course by improving mucosal hydration. Assessing changes in airway and digestive tract m…
View article: Evaluation of the Performance of the Novodiag® Stool Parasites Assay for the Detection of Intestinal Protozoa and Microsporidia
Evaluation of the Performance of the Novodiag® Stool Parasites Assay for the Detection of Intestinal Protozoa and Microsporidia Open
Objectives: We aimed to assess the performance of the Novodiag® Stool Parasites (NSP) assay in the diagnosis of the most common intestinal protozoan and microsporidia infections. Methods: A panel of 167 selected stool samples was retrospec…
View article: Effects of Lumacaftor-Ivacaftor on Airway Microbiota-Mycobiota and Inflammation in Patients with Cystic Fibrosis Appear To Be Linked to Pseudomonas aeruginosa Chronic Colonization
Effects of Lumacaftor-Ivacaftor on Airway Microbiota-Mycobiota and Inflammation in Patients with Cystic Fibrosis Appear To Be Linked to Pseudomonas aeruginosa Chronic Colonization Open
The management of cystic fibrosis has been transformed recently by the advent of CFTR modulators, including lumacaftor-ivacaftor. However, the effects of such therapies on the airway ecosystem, particularly on the microbiota-mycobiota and …
View article: Interest of a Commercialized Pneumocystis jirovecii Quantitative PCR to Discriminate Colonization from Pneumocystis Pneumonia according to the Revised EORTC/MSGERC Criteria
Interest of a Commercialized Pneumocystis jirovecii Quantitative PCR to Discriminate Colonization from Pneumocystis Pneumonia according to the Revised EORTC/MSGERC Criteria Open
Quantitative PCR (qPCR) is highly sensitive to diagnose Pneumocystis jirovecii (Pj) pneumonia (PCP). However, differentiating PCP and colonization remains difficult. This study aimed to establish the performances of the commercialized qPCR…
View article: New Insights into Blood Circulating Lymphocytes in Human Pneumocystis Pneumonia
New Insights into Blood Circulating Lymphocytes in Human Pneumocystis Pneumonia Open
The host lymphocyte response is decisive in Pneumocystis pneumonia (PCP) pathophysiology but little is known of the specific roles of lymphocyte subpopulations in this fungal infection. Peripheral NK, NKT, B, TCD4+ and TCD8+ subpopulations…
View article: Immune Response in Pneumocystis Infections According to the Host Immune System Status
Immune Response in Pneumocystis Infections According to the Host Immune System Status Open
The host immune response is critical in Pneumocystis pneumonia (PCP). Immunocompetent hosts can eliminate the fungus without symptoms, while immunodeficient hosts develop PCP with an unsuitable excessive inflammatory response leading to lu…
View article: Médiateurs lipidiques de l'inflammation et populations lymphocytaires au cours des infections à Pneumocystis : études cliniques et modèle murin
Médiateurs lipidiques de l'inflammation et populations lymphocytaires au cours des infections à Pneumocystis : études cliniques et modèle murin Open
View article: Invasive Aspergillosis Due to <i>Aspergillus</i> Section <i>Usti</i>: A Multicenter Retrospective Study
Invasive Aspergillosis Due to <i>Aspergillus</i> Section <i>Usti</i>: A Multicenter Retrospective Study Open
Background Aspergillus spp. of section Usti (A. ustus) represent a rare cause of invasive aspergillosis (IA). This multicenter study describes the epidemiology and outcome of A. ustus infections. Methods Patients with A. ustus isolated fro…
View article: Misdiagnosis of imported <i>falciparum</i> malaria from African areas due to an increased prevalence of <i>pfhrp2/pfhrp3</i> gene deletion: the Djibouti case
Misdiagnosis of imported <i>falciparum</i> malaria from African areas due to an increased prevalence of <i>pfhrp2/pfhrp3</i> gene deletion: the Djibouti case Open
Following the diagnosis of a falciparum malaria case imported from Djibouti and not detected by a pfHRP2-based rapid diagnostic test (RDT), we investigated the prevalence of the pfhrp2/pfhrp3-deleted parasites in Djibouti usi…
View article: Real-time PCR for diagnosis of imported schistosomiasis
Real-time PCR for diagnosis of imported schistosomiasis Open
Schistosoma PCRs clearly outperform standard microscopy on stools and urine and could be part of reference methods combined with WB-based serology, which remains a gold standard for initial diagnosis. When serological assays are positive a…
View article: Performance evaluation of different strategies based on microscopy techniques, rapid diagnostic test and molecular loop-mediated isothermal amplification assay for the diagnosis of imported malaria
Performance evaluation of different strategies based on microscopy techniques, rapid diagnostic test and molecular loop-mediated isothermal amplification assay for the diagnosis of imported malaria Open
View article: Multicentre study to determine the Etest epidemiological cut-off values of antifungal drugs in Candida spp. and Aspergillus fumigatus species complex
Multicentre study to determine the Etest epidemiological cut-off values of antifungal drugs in Candida spp. and Aspergillus fumigatus species complex Open
View article: Performance of seven commercial automated assays for the detection of low levels of anti-<i>Toxoplasma</i> IgG in French immunocompromised patients
Performance of seven commercial automated assays for the detection of low levels of anti-<i>Toxoplasma</i> IgG in French immunocompromised patients Open
Background : Immunocompromised patients are at high risk for the development of severe toxoplasmosis from tissue cyst reactivation, the most frequently, or from recently acquired acute infections. Knowledge of serologic status is therefore…
View article: Quantitative PCR (qPCR) Detection of Mucorales DNA in Bronchoalveolar Lavage Fluid To Diagnose Pulmonary Mucormycosis
Quantitative PCR (qPCR) Detection of Mucorales DNA in Bronchoalveolar Lavage Fluid To Diagnose Pulmonary Mucormycosis Open
Early diagnosis and treatment are essential to improving the outcome of mucormycosis. The aim of this retrospective study was to assess the contribution of quantitative PCR detection of Mucorales DNA in bronchoalveolar lavage fluids for ea…
View article: Added Value of Next-Generation Sequencing for Multilocus Sequence Typing Analysis of a<i>Pneumocystis jirovecii</i>Pneumonia Outbreak1
Added Value of Next-Generation Sequencing for Multilocus Sequence Typing Analysis of a<i>Pneumocystis jirovecii</i>Pneumonia Outbreak1 Open
Pneumocystis jirovecii is a major threat for immunocompromised patients, and clusters of pneumocystis pneumonia (PCP) have been increasingly described in transplant units during the past decade. Exploring an outbreak transmission network r…
View article: ICE volume 38 issue 2 Cover and Front matter
ICE volume 38 issue 2 Cover and Front matter Open
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