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View article: Atrial fibrillation or flutter in patients undergoing stem cell transplantation, in-hospital and post-discharge outcomes in a large nationwide sample across the United States
Atrial fibrillation or flutter in patients undergoing stem cell transplantation, in-hospital and post-discharge outcomes in a large nationwide sample across the United States Open
Background Stem Cell Transplantation (SCT) is a cornerstone therapy in managing several malignant and benign hematological conditions. Atrial fibrillation/atrial flutter (AF) are commonly encountered in patients receiving SCT. There is a p…
View article: Model for End Stage Liver Disease Excluding International Normalized Ratio Predicts Severe Right Ventricular Failure After HeartMate 3 Implantation in a Contemporary Cohort
Model for End Stage Liver Disease Excluding International Normalized Ratio Predicts Severe Right Ventricular Failure After HeartMate 3 Implantation in a Contemporary Cohort Open
Background Right ventricular failure (RVF) after left ventricular assist devices is associated with significant morbidity and mortality. Therefore, identifying patients at risk for severe RVF is important for clinical decision‐making. Curr…
View article: Coronary artery calcium on lung cancer radiation planning CT aids cardiovascular risk assessment
Coronary artery calcium on lung cancer radiation planning CT aids cardiovascular risk assessment Open
Background Patients with non-small cell lung cancer (NSCLC) undergoing thoracic radiation are at high cardiovascular risk. Semiquantitative assessment of coronary artery calcification (CAC) on baseline planning non-gated chest computed tom…
View article: Predictive Value of VO<sub>2peak</sub>in Adult Congenital Heart Disease in Comparison with Heart Failure with Reduced Ejection Fraction
Predictive Value of VO<sub>2peak</sub>in Adult Congenital Heart Disease in Comparison with Heart Failure with Reduced Ejection Fraction Open
BACKGROUND Peak oxygen consumption (V̇O 2peak ) is used to predict outcomes and the timing of transplantation in patients with heart failure with reduced ejection fraction (HFrEF); V̇O 2peak also has predictive utility in patients with adult…
View article: Coronary Artery Calcium on Lung Cancer Radiation Planning CT Aids Cardiovascular Risk Assessment
Coronary Artery Calcium on Lung Cancer Radiation Planning CT Aids Cardiovascular Risk Assessment Open
Background: Patients with non-small cell lung cancer (NSCLC) undergoing thoracic radiation are at high cardiovascular risk. Semiquantitative assessment of coronary artery calcification (CAC) on baseline planning non-gated chest computed to…
View article: MELD-XI Predicts Severe Right Ventricular Failure after HeartMate 3 Implantation in a Contemporary Cohort
MELD-XI Predicts Severe Right Ventricular Failure after HeartMate 3 Implantation in a Contemporary Cohort Open
Background Right ventricular failure (RVF) after left ventricular assist devices (LVAD) is associated with significant morbidity and mortality and identifying patients at risk for severe RVF is an important clinical goal. Current risk pred…
View article: Intensive Versus Traditional Cardiac Rehabilitation: Mortality and Cardiovascular Outcomes in a 2016–2020 Retrospective Medicare Cohort
Intensive Versus Traditional Cardiac Rehabilitation: Mortality and Cardiovascular Outcomes in a 2016–2020 Retrospective Medicare Cohort Open
BACKGROUND: Traditional cardiac rehabilitation (CR) improves cardiovascular outcomes and reduces mortality, but less is known about the relative benefit of intensive CR (ICR) which incorporates greater lifestyle education through 72 sessio…
View article: Patient and Hospital Characteristics Associated With the Interhospital Transfer of Adult Patients With Sepsis
Patient and Hospital Characteristics Associated With the Interhospital Transfer of Adult Patients With Sepsis Open
IMPORTANCE: The interhospital transfer (IHT) of patients with sepsis to higher-capability hospitals may improve outcomes. Little is known about patient and hospital factors associated with sepsis IHT. OBJECTIVES: We evaluated patterns of h…
View article: The Relationship Between Hospital Capability and Mortality in Sepsis: Development of a Sepsis-Related Hospital Capability Index*
The Relationship Between Hospital Capability and Mortality in Sepsis: Development of a Sepsis-Related Hospital Capability Index* Open
OBJECTIVES: Regionalized sepsis care could improve sepsis outcomes by facilitating the interhospital transfer of patients to higher-capability hospitals. There are no measures of sepsis capability to guide the identification of such hospit…
View article: 60 Derivation and Validation of a Novel Hospital Capability Score for Sepsis
60 Derivation and Validation of a Novel Hospital Capability Score for Sepsis Open
OBJECTIVES/GOALS: Regionalized sepsis care could improve sepsis outcomes. There are no measures of sepsis capability to guide the identification of hospitals that can best serve sepsis patients. We derived Capability-Based (CB) scores from…
View article: Sex‐related differences in premature cardiovascular disease in familial hypercholesterolemia
Sex‐related differences in premature cardiovascular disease in familial hypercholesterolemia Open
These data confirm that high percentages of women and men with FH develop premature ASCVD, and suggest that FH may narrow the observed sex difference in premature ASCVD onset. These data support more aggressive prevention and treatment str…
View article: Computerized electrocardiogram data transformation enables effective algorithmic differentiation of wide<scp>QRS</scp>complex tachycardias
Computerized electrocardiogram data transformation enables effective algorithmic differentiation of wide<span>QRS</span>complex tachycardias Open
Background Accurate automated wide QRS complex tachycardia (WCT) differentiation into ventricular tachycardia (VT) and supraventricular wide complex tachycardia (SWCT) can be accomplished using calculations derived from computerized electr…
View article: Coronary calcification is independently associated with major adverse cardiovascular events in men with recurrent prostate cancer while aortic calcification is not
Coronary calcification is independently associated with major adverse cardiovascular events in men with recurrent prostate cancer while aortic calcification is not Open
Background Cardiovascular disease is an important cause of morbidity and mortality in men with prostate cancer. Coronary and aortic calcification have been associated with major adverse cardiovascular events (MACE) in the general populatio…
View article: Benefits of the First Pritikin Outpatient Intensive Cardiac Rehabilitation Program
Benefits of the First Pritikin Outpatient Intensive Cardiac Rehabilitation Program Open
Purpose: Intensive cardiac rehabilitation (ICR) is a comprehensive, medically supervised exercise treatment program covered by Medicare for patients with approved cardiac diagnoses. The aim of this study was to determine the benefits of th…
View article: Demographic, behavioral, dietary, and clinical predictors of high-sensitivity C-reactive protein: The National Health and Nutrition Examination Surveys (NHANES)
Demographic, behavioral, dietary, and clinical predictors of high-sensitivity C-reactive protein: The National Health and Nutrition Examination Surveys (NHANES) Open
Funding Acknowledgements Type of funding sources: None. Introduction High-sensitivity C-reactive protein (hs-CRP), a marker of inflammation, is associated with atherosclerosis, and recent studies indicate that therapies targeting inflammat…
View article: Assessment of Nonfatal Myocardial Infarction as a Surrogate for All-Cause and Cardiovascular Mortality in Treatment or Prevention of Coronary Artery Disease
Assessment of Nonfatal Myocardial Infarction as a Surrogate for All-Cause and Cardiovascular Mortality in Treatment or Prevention of Coronary Artery Disease Open
IMPORTANCE: Although nonfatal myocardial infarction (MI) is associated with an increased risk of mortality, evidence validating nonfatal MI as a surrogate end point for all-cause or cardiovascular (CV) mortality is lacking. OBJECTIVE: To e…
View article: Is myocardial infarction a surrogate endpoint for all-cause mortality? A trial-level meta-analysis of 144 randomized controlled trials enrolling 1.2 million patients from 1972–2020
Is myocardial infarction a surrogate endpoint for all-cause mortality? A trial-level meta-analysis of 144 randomized controlled trials enrolling 1.2 million patients from 1972–2020 Open
Background Nonfatal myocardial infarction (MI) is commonly included as an endpoint in studies of treatment or prevention of coronary artery disease driven by the assumption that MI is a surrogate for downstream mortality and that preventin…
View article: Prognostic significance of longitudinal strain in dilated cardiomyopathy with recovered ejection fraction
Prognostic significance of longitudinal strain in dilated cardiomyopathy with recovered ejection fraction Open
Objective Patients with non-ischaemic dilated cardiomyopathy (NICM) may experience a normalisation in left ventricular ejection fraction (LVEF). Although this correlates with improved prognosis, it does not correspond to a normalisation in…
View article: Racial Disparities in Modifiable Risk Factors and Statin Usage in Black Patients With Familial Hypercholesterolemia
Racial Disparities in Modifiable Risk Factors and Statin Usage in Black Patients With Familial Hypercholesterolemia Open
Background Black men and women are at higher risk for, and suffer greater morbidity and mortality from, atherosclerotic cardiovascular disease (ASCVD) compared with adults of European Ancestry (EA). Black patients with familial hypercholes…
View article: The Impact of COVID-19 on Dual-Physician Couples: A Disproportionate Burden on Women Physicians
The Impact of COVID-19 on Dual-Physician Couples: A Disproportionate Burden on Women Physicians Open
Background: Currently, physicians face an unprecedented crisis with the novel coronavirus disease 2019 (COVID-19) pandemic. The impact of the pandemic on dual-physician households remains unknown. In this survey study, we examined the impa…
View article: Unsupervised cluster analysis of patients with recovered left ventricular ejection fraction identifies unique clinical phenotypes
Unsupervised cluster analysis of patients with recovered left ventricular ejection fraction identifies unique clinical phenotypes Open
Background Patients with heart failure (HF) with recovered ejection fraction (HFrecEF) are a recently identified cohort that are phenotypically and biologically different from HFrEF and HFpEF patients. Whether there are unique phenotypes a…