Elena Hoffer
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View article: Graded expression of the chemokine receptor CX3CR1 marks differentiation states of human and murine T cells and enables cross-species interpretation
Graded expression of the chemokine receptor CX3CR1 marks differentiation states of human and murine T cells and enables cross-species interpretation Open
T cells differentiate into functionally distinct states upon antigen encounter. These states are delineated by different cell surface markers for murine and human T cells, which hamper cross-species translation of T cell properties. We aim…
View article: T cells in resolved allergic contact dermatitis steer tissue inflammation and <scp>MMP</scp>‐12–driven tissue modulation
T cells in resolved allergic contact dermatitis steer tissue inflammation and <span>MMP</span>‐12–driven tissue modulation Open
Tissue resident memory T cells contribute to localized immunity in barrier tissues such as the skin1 but are also implicated in local relapse of focal inflammatory skin diseases, including allergic contact dermatitis (ACD) and psoriasis.2-…
View article: Immune Cells and Immunosenescence
Immune Cells and Immunosenescence Open
Aging is associated with progressive loss of physiological integrity, leading to impaired physical and mental functions as well as increased morbidity and mortality. With advancing age, the immune system is no longer able to adequately con…