Explanipedia

Comparative Assessment of Lower Urinary Tract Infections in Hospitalized Adults from Western Romania: A Retrospective Cohort with Microbiological Analysis Open

Adela Benea, Mirela Turaiche, Ovidiu Roșca, Elena Hogea, Madalina-Ianca Suba , et al. · 2025

Urinary tract infections (UTIs) remain a leading cause of healthcare-associated morbidity, particularly in patients with indwelling urinary catheters. This study aimed to compare catheter-associated (CAUTIs) and non-catheter-associated UTI…

Bacterial Superinfections After SARS-CoV-2 Pneumonia: Antimicrobial Resistance Patterns, Impact on Inflammatory Profiles, Severity Scores, and Clinical Outcomes Open

Petrinela Daliu, Iulia Bogdan, Ovidiu Roșca, Alexandra Laura Aelenei, Ioan Ovidiu Sîrbu , et al. · 2025

Background and Objectives: Secondary bacterial pneumonia can substantially worsen the clinical trajectory of patients hospitalized for Coronavirus Disease 2019 (COVID-19). This study aimed to characterize bacterial superinfections in COVID…

Phenotypes of Exacerbations in Chronic Obstructive Pulmonary Disease Open

Lucreția Avram, Tamara Mirela Poroșnicu, Patricia Hogea, Emanuela Tudorache, Elena Hogea , et al. · 2025

Chronic obstructive pulmonary disease (COPD) is a chronic respiratory disease with an important public health challenge and a major burden on health-care resources, having a progressive character with constant deterioration of lung functio…

Fungal Pulmonary Coinfections in COVID-19: Microbiological Assessment, Inflammatory Profiles, and Clinical Outcomes Open

Petrinela Daliu, Iulia Bogdan, Ovidiu Roșca, Monica Licker, Livia Stanga , et al. · 2025

Background and Objectives: Secondary pulmonary fungal infections in coronavirus disease 2019 (COVID-19) remain underexplored despite emerging reports linking them to heightened morbidity. Comorbidities, steroid use, and prolonged hospital …

Six-Year Epidemiologic Analysis of Antibiotic Resistance Patterns of Klebsiella pneumoniae Infections in a Tertiary Healthcare Center in Western Romania Open

Elena Hogea, Alexandra-Cristina Muntean, Oana Plavițu, Adelina Fratutu, Iulia Bogdan , et al. · 2024

Background and Objectives: Klebsiella pneumoniae is a major nosocomial pathogen with a remarkable ability to develop resistance to multiple antibiotics, posing significant treatment challenges. This study aims to evaluate the antimicrobial…

Evaluation of Inflammatory Status in COVID-19 Patients with Chronic Kidney Disease: A Comparative Analysis Based on Creatinine Clearance Levels Open

Andreea Banta, Daniela Roşca, Ovidiu Roșca, Iulia Bogdan, Teodor Cerbulescu , et al. · 2024

Background and Objectives: Patients with chronic kidney disease (CKD) are at increased risk of severe COVID-19 outcomes due to their compromised immune systems and chronic inflammatory state. This study aimed to evaluate and compare the in…

Prognostic Utility of dNLR, ALRI, APRI, and SII in COVID-19 Patients with Diabetes: A Cross-Sectional Study Open

Alexandra-Ioana Dănilă, Flavius Cioca, Sai Teja Gadde, Sai Praveen Daruvuri, Romulus Timar , et al. · 2024

The coronavirus disease 2019 (COVID-19) pandemic has necessitated the identification of biomarkers that can predict disease severity, particularly in vulnerable populations such as individuals with diabetes. This study aims to evaluate the…

Microbiological and Imaging-Based Evaluations of Photodynamic Therapy Combined with Er:YAG Laser Therapy in the In Vitro Decontamination of Titanium and Zirconia Surfaces Open

Ioana-Roxana Munteanu, Ruxandra Elena Luca, Elena Hogea, Ralph-Alexandru Erdelyi, Virgil-Florin Duma , et al. · 2024

The oral cavity’s soft and hard tissues create a conducive environment for microbial proliferation and biofilm development, facilitating the colonization of prosthodontic and implant materials such as titanium (Ti) and zirconia (Zr). This …

Antibiotic Resistance Trends in Uropathogens during the COVID-19 Pandemic in Western Romania: A Cross-Sectional Study Open

Elena Hogea, Alexandra Cristina Muntean, Felix Bratosin, Iulia Bogdan, Oana Plavițu , et al. · 2024

The emergence and spread of antimicrobial resistance have been significant global health challenges, exacerbated by the COVID-19 pandemic. As healthcare systems faced unprecedented pressures, the management of non-COVID conditions, includi…

Risk Factors for Pulmonary Embolism in Individuals Infected with SARS-CoV2—A Single-Centre Retrospective Study Open

Alexandra Herlo, Adelina Raluca Marinescu, Talida Georgiana Cut, Ruxandra Laza, Cristian Oancea , et al. · 2024

The emergence of SARS-CoV2 has presented itself as a significant global health crisis. The prevalence of thrombotic events is known to be high in these patients, affecting various organ systems, sometimes leading to cutaneous thrombosis, p…

Post-Infection Oscillometry and Pulmonary Metrics in SARS-CoV-2 Patients: A 40-Day Follow-Up Study Open

Noemi Suppini, Cristian Oancea, Ovidiu Fira‐Mladinescu, Daniel Trăilă, Camelia Corina Pescaru , et al. · 2023

The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has had significant impacts on pulmonary function. This study aimed to comprehensively evaluate pulmonary function and structure in patients 40 days post-SARS-CoV-2 infection, employin…

Antimicrobial Resistance Pattern of Multidrug-Resistant Bacteria Isolated from COVID-19 Patients Open

Elena Hogea, Alexandra-Cristina Muntean, Adelina Fratutu, Oana Plavițu, Cristian Oancea , et al. · 2023

A Retrospective Assessment of Sputum Samples and Antimicrobial Resistance in COVID-19 Patients Open

Talida Georgiana Cut, Adelina Mavrea, Alin Adrian Cumpănaş, Dorin Novacescu, Cristian Oancea , et al. · 2023

Data on bacterial or fungal pathogens and their impact on the mortality rates of Western Romanian COVID-19 patients are scarce. As a result, the purpose of this research was to determine the prevalence of bacterial and fungal co- and super…

A Case Report of concurrent SARS-CoV-2 infection and multi-drug-resistant tuberculous meningitis Open

Adriana Socaci, Camil Mihuta, Cristian Oancea, Elena Hogea · 2023

Infrequently documented, drug-resistant tuberculous meningitis presents diagnostic and treatment challenges, particularly during SARS-CoV-2 coinfection. Timely identification is crucial to prevent severe complications, yet the optimal trea…

Dental-Plaque Decontamination around Dental Brackets Using Antimicrobial Photodynamic Therapy: An In Vitro Study Open

D. E. Bojoga, Mariana Miron, Elena Hogea, Cornelia Muntean, Darinca Carmen Todea · 2021

Background: In orthodontic therapy, the enamel around brackets is very susceptible to bacterial-plaque retention, which represents a risk factor for dental tissues. The aim of this study was to evaluate the effect of methylene blue and a c…

Long noncoding RNAs may impact podocytes and proximal tubule function through modulating miRNAs expression in Early Diabetic Kidney Disease of Type 2 Diabetes Mellitus patients Open

Ligia Petrică, Elena Hogea, Florica Gădălean, Adrian Vlad, Mihaela Vlad , et al. · 2021

Aims: Long noncoding RNAs (lncRNAs) play key roles in the pathophysiology of DKD involving actions of microRNAs (miRNAs). The aims of the study were to establish the involvement of selected lncRNAs in the epigenetic mechanisms of po…

Smartphone Use and Postural Balance in Healthy Young Adults Open

Roxana Ramona Onofrei, Elena Amaricăi, Oana Suciu, Vlad Laurenţiu David, Andreea Luciana Rață , et al. · 2020

Maintaining an upright posture while talking or texting on the phone is a frequent dual-task demand. Using a within-subjects design, the aim of the present study was to assess the impact of a smartphone conversation or message texting on s…

Microarray Technology for the Detection of Antimicrobial Resistance Genes Present in Hospital and Community Acquired Methicillin Resistant S.aureus Strains Open

Monica Licker, Andrei Anghel, Roxana Moldovan, Elena Hogea, Delia Muntean , et al. · 2017

Antimicrobial resistance (AMR) represents a real burden for the modern medicine. One of the most frecvently isolated hospital acquired (HA) pathogens wordlwide, is Methicillin resistant Staphylococcus aureus (MRSA). Recently not only HA, b…

Intensive care antibiotic consumption and resistance patterns: a cross-correlation analysis Open

Luminița Bădițoiu, Carmen Axente, Diana Lungeanu, Delia Muntean, Florin George Horhat , et al. · 2017

The cross-correlation coefficients and the fitted regression models provide additional evidence that resistance during the a given quarter depends not only on the consumption of antibacterial chemotherapeutic drugs in both that quarter and…

Beta-lactam Resistance Mechanisms in Pathogens Isolated from Patients Admitted to Intensive Care Unit Open

Carmen Axente, Delia Muntean, Luminița Bădițoiu, Roxana Moldovan, Elena Hogea , et al. · 2017

Intensive care units (ICUs) are often referred to as the epicentre of infection diseases in a hospital. Many studies highlighted the importance of using local antimicrobial resistance data, to guide empirical antibiotic therapy. As a conse…

Antimicrobial consumption, costs and resistance patterns: a two year prospective study in a Romanian intensive care unit Open

Carmen Axente, Monica Licker, Roxana Moldovan, Elena Hogea, Delia Muntean , et al. · 2017

Microbial biofilm in human health - an updated theoretical and practical insight Open

Monica Licker, Roxana Moldovan, Elena Hogea, Delia Muntean, Florin George Horhat , et al. · 2017

The term biofilm designates an aggregate of microorganisms belonging to one or more species which adhere to various surfaces but also to each another. These microbial communities are included and interconnected within an organic structure …

MOESM2 of Intensive care antibiotic consumption and resistance patterns: a cross-correlation analysis Open

Luminița Bădițoiu, Carmen Axente, Diana Lungeanu, Delia Muntean, Florin George Horhat , et al. · 2017

Additional file 2. The resistance phenotypes.

MOESM1 of Intensive care antibiotic consumption and resistance patterns: a cross-correlation analysis Open

Luminița Bădițoiu, Carmen Axente, Diana Lungeanu, Delia Muntean, Florin George Horhat , et al. · 2017

Additional file 1. The consumption of antibacterial drugs.

Urinary tract infections in Romanian patients with diabetes: prevalence, etiology, and risk factors Open

Teodora Chiţă, Bogdan Timar, Delia Muntean, Luminița Bădițoiu, Florin George Horhat , et al. · 2016

UTIs are a frequent condition associated with DM. It is necessary to improve the care and the screening of UTIs in patients with DM to prevent the occurrence of possible associated severe renal complications.

Study on the influence of laser radiation in the plaque compared with 0.2% chlorhexidine – microbiological and microscopic analysis Open

Daliana Mocuţa, Carmen Todea, Andreea Lazea, Elena Hogea, Cornelia Muntean · 2016

Objectives. The aim of this study was to evaluate de antimicrobian effect of laser radiation and chlorhexidine 0.2% treatment for reducing the number of pathogenic oral microorganisms, especially Streptococcus mutans, adjacent orthodontic …

Germinated and Ungerminated Seeds Extract from Two <i>Lupinus</i> Species: Biological Compounds Characterization and In Vitro and In Vivo Evaluations Open

Bogdan Andor, Corina Danciu, Ersilia Alexa, István Zupkó, Elena Hogea , et al. · 2016

In recent years, nutraceuticals attracted a great amount of attention in the biomedical research due to their significant contribution as natural agents for prevention of various health issues. Ethanolic extracts from the ungerminated and …

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