Elena Tsitsami
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View article: Anakinra for resistant Kawasaki disease in an infant: case report and literature review
Anakinra for resistant Kawasaki disease in an infant: case report and literature review Open
Resistant Kawasaki has been associated with the aggressive development of large coronary aneurysms, despite prompt treatment. In this paper, we present an infant who presented with resistant Kawasaki. Although initially he seemed to deferv…
View article: Natural autoimmunity in oligoarticular juvenile idiopathic arthritis
Natural autoimmunity in oligoarticular juvenile idiopathic arthritis Open
Background Oligoarticular juvenile idiopathic arthritis (oligo-JIA) is considered as an antigen-driven lymphocyte-mediated autoimmune disease. Natural antibodies (NAbs) are pre-immune antibodies produced in the absence of exogenous antigen…
View article: Natural autoimmunity in oligoarticular juvenile idiopathic arthritis
Natural autoimmunity in oligoarticular juvenile idiopathic arthritis Open
Oligoarticular juvenile idiopathic arthritis (oligo-JIA) is classically thought of as an antigen-driven lymphocyte-mediated autoimmune disease. Considering the major immunoregulatory role of natural antibodies (NAbs) in homeostasis and aut…
View article: Anakinra in Patients With Systemic Juvenile Idiopathic Arthritis: Long-term Safety From the Pharmachild Registry
Anakinra in Patients With Systemic Juvenile Idiopathic Arthritis: Long-term Safety From the Pharmachild Registry Open
Objective To evaluate the long-term safety profile of anakinra in patients with systemic juvenile idiopathic arthritis (sJIA). Methods Data from patients with sJIA enrolled in the Pharmachild registry ( ClinicalTrials.gov : NCT03932344 ) p…
View article: Development and Testing of Reduced Versions of the Manual Muscle Test-8 in Juvenile Dermatomyositis
Development and Testing of Reduced Versions of the Manual Muscle Test-8 in Juvenile Dermatomyositis Open
Objective. To develop and test shortened versions of the Manual Muscle Test-8 (MMT-8) in juvenile dermatomyositis (JDM). Methods. Construction of reduced tools was based on a retrospective analysis of individual scores of MMT-8 muscle grou…
View article: <i>SIAE</i> Rare Variants in Juvenile Idiopathic Arthritis and Primary Antibody Deficiencies
<i>SIAE</i> Rare Variants in Juvenile Idiopathic Arthritis and Primary Antibody Deficiencies Open
Sialic acid acetylesterase (SIAE) deficiency was suggested to lower the levels of ligands for sialic acid-binding immunoglobulin-like receptors, decreasing the threshold for B-cell activation. In humans, studies of rare heterozygous loss-o…