Eleonora Botter
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View article: Unlocking the potential of organopalladium complexes for high-grade serous ovarian cancer therapy
Unlocking the potential of organopalladium complexes for high-grade serous ovarian cancer therapy Open
High-Grade Serous Ovarian Cancer (HGSOC) is the most common and lethal subtype of ovarian cancer, known for its high aggressiveness and extensive genomic alterations.
View article: Synthesis of Gold(I) and Palladium(II) Complexes Bearing <i>N</i>‐Heterocyclic Carbene Thioglucosides with Selective Cytotoxicity Towards Ovarian Cancer Cells
Synthesis of Gold(I) and Palladium(II) Complexes Bearing <i>N</i>‐Heterocyclic Carbene Thioglucosides with Selective Cytotoxicity Towards Ovarian Cancer Cells Open
We report the development of an efficient and versatile synthetic protocol for the preparation of gold(I) and palladium(II) complexes bearing N‐heterocyclic carbene (NHC) thioglucosides and their azolium precursors. Gold(I) and Nolan‐type …
View article: Liposomal Formulations of Metallodrugs for Cancer Therapy
Liposomal Formulations of Metallodrugs for Cancer Therapy Open
The search for new antineoplastic agents is imperative, as cancer remains one of the most preeminent causes of death worldwide. Since the discovery of the therapeutic potential of cisplatin, the study of metallodrugs in cancer chemotherapy…
View article: Unlocking the Potential of Organopalladium Complexes for High-Grade Serous Ovarian Cancer Therapy
Unlocking the Potential of Organopalladium Complexes for High-Grade Serous Ovarian Cancer Therapy Open
High-Grade Serous Ovarian Cancer (HGSOC) is the most common and lethal subtype of ovarian cancer, known for its high aggressiveness and extensive genomic alterations. Typically diagnosed at an advanced stage, HGSOC presents formidable chal…
View article: Rational Design of Palladium(II) Indenyl and Allyl Complexes Bearing Phosphine and Isocyanide Ancillary Ligands with Promising Antitumor Activity
Rational Design of Palladium(II) Indenyl and Allyl Complexes Bearing Phosphine and Isocyanide Ancillary Ligands with Promising Antitumor Activity Open
A new class of palladium–indenyl complexes characterized by the presence of one bulky alkyl isocyanide and one aryl phosphine serving as ancillary ligands has been prepared, presenting high yields and selectivity. All the new products were…
View article: Gold(I)‐<i>N</i>‐Heterocyclic Carbene Synthons in Organometallic Synthesis
Gold(I)‐<i>N</i>‐Heterocyclic Carbene Synthons in Organometallic Synthesis Open
The prominent role of gold‐ N ‐heterocyclic carbene (NHC) complexes in numerous research areas such as homogeneous (photo)catalysis, medicinal chemistry and materials science has prompted organometallic chemists to design gold‐based syntho…