Eleonora Bunsow
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View article: Nasopharyngeal Codetection <i>of Haemophilus influenzae</i> and <i>Streptococcus pneumoniae</i> Shapes Respiratory Syncytial Virus Disease Outcomes in Children
Nasopharyngeal Codetection <i>of Haemophilus influenzae</i> and <i>Streptococcus pneumoniae</i> Shapes Respiratory Syncytial Virus Disease Outcomes in Children Open
Background The role of nasopharyngeal bacteria in respiratory syncytial virus (RSV) disease has been underestimated. We measured the frequency and burden of respiratory bacteria in the upper respiratory tract of infants with RSV infection …
View article: 118. Nasopharyngeal (NP) Bacterial Detection in Infants With Respiratory Syncytial Virus (RSV) Infection: Impact on Clinical Outcomes
118. Nasopharyngeal (NP) Bacterial Detection in Infants With Respiratory Syncytial Virus (RSV) Infection: Impact on Clinical Outcomes Open
Background Previous studies suggest that RSV increases NP bacterial colonization and may facilitate infection. However, the role of NP colonization with potentially pathogenic bacteria (PPB) in the pathogenesis of RSV bronchiolitis is not …
View article: Interferon gene expression as marker of immune maturation and response to vaccination
Interferon gene expression as marker of immune maturation and response to vaccination Open
Background Interferons (IFN) play a major role in regulating innate and adaptive immune responses. Studies in adults and older children demonstrated significant correlations between IFN gene expression and antibody responses to influenza v…
View article: Nasopharyngeal Microbiota, Host Transcriptome, and Disease Severity in Children with Respiratory Syncytial Virus Infection
Nasopharyngeal Microbiota, Host Transcriptome, and Disease Severity in Children with Respiratory Syncytial Virus Infection Open
Our data suggest that interactions between RSV and nasopharyngeal microbiota might modulate the host immune response, potentially affecting clinical disease severity.