Elham Aflaki
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View article: Investigation of clinical characteristics of COVID-19 infection in rheumatoid patients on immunosuppressive drugs: a retrospective case–control study
Investigation of clinical characteristics of COVID-19 infection in rheumatoid patients on immunosuppressive drugs: a retrospective case–control study Open
Backgrounds Cytokine storm has been considered a major pathogenic in severe COVID-19 patients with severe disease. Inflammatory cytokines, such as interleukin-6(IL-6), IL-1, and tumor necrosis factor alpha (TNF-α) released from the lung ep…
View article: Investigation of Clinical Characteristics of COVID-19 Infection in Rheumatoid Patients on Immunosuppressive Drugs: A Cross-sectional Study
Investigation of Clinical Characteristics of COVID-19 Infection in Rheumatoid Patients on Immunosuppressive Drugs: A Cross-sectional Study Open
Backgrounds: Cytokine storm has been considered as the main pathogenesis in COVID-19 patients with severe disease. Inflammatory cytokines, such as interleukin-6(IL-6), IL-1, and tumor necrosis factor alpha (TNF-α) released from the lung ep…
View article: Indications, response, and side effects of biologic treatment in Behçet’s disease: an 8-year study with follow-up
Indications, response, and side effects of biologic treatment in Behçet’s disease: an 8-year study with follow-up Open
Introduction The treatment of Behçet’s disease has improved significantly with the introduction of biologic therapies. However, there is still a need for more information about their use. This study aimed to evaluate the indications, respo…
View article: Validation and Cultural Adaptation of Persian Version of Multidimensional Health Assessment Questionnaire in Rheumatoid Arthritis Patients
Validation and Cultural Adaptation of Persian Version of Multidimensional Health Assessment Questionnaire in Rheumatoid Arthritis Patients Open
The Persian form of MDHAQ is a reliable and valid instrument for the routine evaluation of RA patients in rheumatology clinics in Iranian RA patients.
View article: Evaluation of Sex Hormones Serum Profile in Male Patients with Behcet’s Disease
Evaluation of Sex Hormones Serum Profile in Male Patients with Behcet’s Disease Open
Objectives: This cross-sectional study has been done on people with Behcet`s disease referred to Shahid Motahri Clinic and Shiraz Dental Faculty during 2020. Materials and Method: Twenty five men with new confirmed Behcet's disease and twe…
View article: Economic Burden of Rheumatoid Arthritis In Iran: A Societal Perspective Economic Burden of R.A.
Economic Burden of Rheumatoid Arthritis In Iran: A Societal Perspective Economic Burden of R.A. Open
Background : Rheumatoid arthritis (RA) is a progressive, chronic systemic inflammatory disease and impose a significant economic burden on patients and societies if not controlled. This study aimed to determine the economic burden of RA in…
View article: Economic Burden of Rheumatoid Arthritis in Iran: A Societal Perspective Economic Burden of R.A.
Economic Burden of Rheumatoid Arthritis in Iran: A Societal Perspective Economic Burden of R.A. Open
Background : Rheumatoid arthritis (RA) is a progressive, chronic systemic inflammatory disease and impose a significant economic burden on patients and societies if not controlled. This study aimed to determine the economic burden of RA in…
View article: Cost-Effectiveness of Osteoporosis Screening in Women Over 40-Year-Old
Cost-Effectiveness of Osteoporosis Screening in Women Over 40-Year-Old Open
Osteoporosis is a disease recognized by bone density reduction and is particularly common among older women, which imposes them to fractures. The evidence shows that if do no serious conflict with this issue, in the far little future, huge…
View article: Pathergy test with a 23G needle with and without self-saliva in patients with Behçet’s disease, recurrent aphthous stomatitis and control group compared to the 20G test
Pathergy test with a 23G needle with and without self-saliva in patients with Behçet’s disease, recurrent aphthous stomatitis and control group compared to the 20G test Open
Introduction The pathergy test (PT) is part of the diagnostic criteria of Behçet’s disease (BD). Factors like needle character and number of punctures can affect the sensitivity of PT. We tried to compare its positivity using a thinner nee…
View article: Experiences of the Patients with Behcet's Syndrom from Adherence to Treatment: A Qualitative Content Analysis.
Experiences of the Patients with Behcet's Syndrom from Adherence to Treatment: A Qualitative Content Analysis. Open
The barriers to and facilitators of treatment adherence as well as the missing aspects of the treatment program of patients with BS were identified. Adherence to treatment is not only determined by the patients, but also affected by the su…
View article: Genetic Association of Interkeukin-21 and Interleukin-23 Receptor Polymorphisms With Systemic Lupus Erythematosus in Iranian Population
Genetic Association of Interkeukin-21 and Interleukin-23 Receptor Polymorphisms With Systemic Lupus Erythematosus in Iranian Population Open
Objective : T helper 17 (Th17) is believed to play a crucial role in pathophysiology of systemic lupus erythematosus (SLE). Our study aimed to detect the potential association of IL-21 and IL-23R polymorphisms with susceptibility to SLE. M…
View article: The Effectiveness of Acceptance and Commitment Therapy on Depression and Follow-Up Treatment of Patients with Systemic Lupus
The Effectiveness of Acceptance and Commitment Therapy on Depression and Follow-Up Treatment of Patients with Systemic Lupus Open
The Effectiveness of Acceptance and Commitment Therapy on Depression and Follow-Up Treatment of Patients with Systemic Lupus
View article: Cost‐Effectiveness Analysis of Biopharmaceuticals for Treating Rheumatoid Arthritis: Infliximab, Adalimumab, and Etanercept
Cost‐Effectiveness Analysis of Biopharmaceuticals for Treating Rheumatoid Arthritis: Infliximab, Adalimumab, and Etanercept Open
Introduction . Rheumatoid arthritis (RA) is a chronic progressive inflammatory disease that causes joint destruction. The condition imposes a significant economic burden on patients and societies. The present study is aimed at evaluating t…
View article: Quality of Life Assessment in Patients with Behçet's Disease using the Persian Version of the Leeds BD-QoL Questionnaire.
Quality of Life Assessment in Patients with Behçet's Disease using the Persian Version of the Leeds BD-QoL Questionnaire. Open
BD patients had a lower QoL than healthy individuals, specifically in the physical health and psychological health domains. An increase in disease activity and severity was associated with a reduced QoL. The Persian version of the Leeds BD…
View article: The Patients’ Beliefs Regarding the Role of Food, Mucosal Trauma, Menstruation, and Psychological Stress in the Recurrence of Behçet’s Disease Symptoms
The Patients’ Beliefs Regarding the Role of Food, Mucosal Trauma, Menstruation, and Psychological Stress in the Recurrence of Behçet’s Disease Symptoms Open
Behçet’s disease is a systemic vasculitis. Mucocutaneous involvement is the most prominent finding, but triggering factors are not well-known. We decided to assess the beliefs of patients with Behçet’s disease regarding the potential role …
View article: Inflammatory and T Helper 17/ Regulatory T Cells Related Cytokines Balance in Cutaneous Lupus Erythematosus (CLE)
Inflammatory and T Helper 17/ Regulatory T Cells Related Cytokines Balance in Cutaneous Lupus Erythematosus (CLE) Open
The cutaneous lupus erythematosus (CLE) is a common manifestation among systemic lupus erythematosus (SLE) patients. Malar rash and discoid lupus (DLE) are in the category of acute and chronic CLE, respectively. The pathogenesis of CLE is …
View article: Western and Healthy Dietary Patterns and Risk of Rheumatoid Arthritis: A Case-Control Study
Western and Healthy Dietary Patterns and Risk of Rheumatoid Arthritis: A Case-Control Study Open
Background and Objectives: Rheumatoid arthritis (RA) is an inflammatory autoimmune disease characterized by swelling, stiffness and pain in body joints.Based on the epidemiological studies, RA is less severe in Southern Mediterranean regio…
View article: Prevalence of human papilloma virus infections among women with systemic lupus erythematosus
Prevalence of human papilloma virus infections among women with systemic lupus erythematosus Open
Systemic lupus erythematosus (SLE) is considered one of the risk factors for cervical cytological abnormalities and high-risk HPV infection. However, there is a scarcity of data about the prevalence of high-risk HPV infection in patients w…
View article: Frequency of HLA-B5, HLA-B51 and HLA-B27 in patients with idiopathic uveitis and Behçet’s disease: a case-control study
Frequency of HLA-B5, HLA-B51 and HLA-B27 in patients with idiopathic uveitis and Behçet’s disease: a case-control study Open
Objectives Idiopathic uveitis is the most common form of uveitis in most countries. Uveitis affects about 40–80% of patients with Behçet’s disease (BD). Class I, HLA-B5, and its subclass B51 allele have the strongest association with BD, b…
View article: Health-Related Quality of Life in Patients with Systemic Lupus Erythematosus and Rheumatoid Arthritis Compared to the Healthy Population in Shiraz, Iran
Health-Related Quality of Life in Patients with Systemic Lupus Erythematosus and Rheumatoid Arthritis Compared to the Healthy Population in Shiraz, Iran Open
Background: Systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) are chronic and complex autoimmune diseases, involving multiple organs. Therefore, quality of life (QoL) in SLE and RA patients can be affected. The current study…
View article: Medicinal Plants for Joint Pain in Traditional Persian Medicine
Medicinal Plants for Joint Pain in Traditional Persian Medicine Open
Joint pains can be resulted by many factors of which osteoarthritis (OA) and rheumatoid arthritis (RA) are the most popular ones. Treatment of both conditions usually involves pain killers. Chronic joint pains are associated with a high us…
View article: Randomized Clinical Trial of Peganum Oil for Knee Osteoarthritis
Randomized Clinical Trial of Peganum Oil for Knee Osteoarthritis Open
Osteoarthritis affects about 50% of people aged older than 65 years. Pain is the most important symptom in this disease. Today public interest in the use of complementary medicine, especially traditional herbal medicines has increased. The…
View article: Determination of serum visfatin levels in patients with Behçet’s disease: A case–control study
Determination of serum visfatin levels in patients with Behçet’s disease: A case–control study Open
Behçet's disease (BD) is an inflammatory, systemic and chronic disorder with unknown etiology affecting multiple systems. Visfatin is a new adipokine with insulin-mimetic properties and pro-inflammatory function. The serum visfatin levels …