Elham Amjadi
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View article: Integrative Single-Cell Transcriptomics and Co-Expression Network Analysis Identify SIMALR as a Prognostic Immune-Related LncRNA in Breast Cancer: In Silico Analysis and Validation
Integrative Single-Cell Transcriptomics and Co-Expression Network Analysis Identify SIMALR as a Prognostic Immune-Related LncRNA in Breast Cancer: In Silico Analysis and Validation Open
Purpose This study aimed to identify and characterize irLncRNAs associated with prognosis and immune modulation in breast cancer. Methods We integrated single-cell RNA sequencing hdWGCNA and bulk RNA-seq differential expression analysis re…
View article: A comprehensive dataset for understanding immune dynamics in colorectal cancer
A comprehensive dataset for understanding immune dynamics in colorectal cancer Open
Colorectal cancer (CRC), the second most common cause of cancer death in the world, can be divided by the location of the primary tumor in the large intestine: right and left colon, and rectum. Based on the location, CRC shows different mo…
View article: Mitigating the Oncogenic Roles of miR-629-5p and miR-660-5p Through Direct Binding by Two Potential Drug Targets for Colorectal Cancer Prevention
Mitigating the Oncogenic Roles of miR-629-5p and miR-660-5p Through Direct Binding by Two Potential Drug Targets for Colorectal Cancer Prevention Open
Background: Many studies have reported the oncogenic roles of microRNA (miRNA)-629-5p and miRNA-660-5p in various cancers. This study aimed to elucidate the oncogenic roles of miRNA-629-5p and miRNA-660-5p, focusing on their potential cont…
View article: The Prevalence of PD-L1 Expression in Triple-Negative Breast Cancer Patients and Its Correlation with Survival Rates and Other Prognostic Factors: A Survival Analysis
The Prevalence of PD-L1 Expression in Triple-Negative Breast Cancer Patients and Its Correlation with Survival Rates and Other Prognostic Factors: A Survival Analysis Open
Background: Triple-negative breast cancer (TNBC) is a leading cause of cancer-related mortality among women, with a poor prognosis. The programmed cell death 1 (PD-1) pathway has emerged as a potential immunotherapy target. This study aime…
View article: New long noncoding RNA biomarkers and ceRNA networks on miR-616-3p in colorectal cancer: Bioinformatics-based study
New long noncoding RNA biomarkers and ceRNA networks on miR-616-3p in colorectal cancer: Bioinformatics-based study Open
Background: Cancer development is aided by the role of long noncoding RNAs (lncRNAs) that act as competing endogenous RNAs (ceRNAs) absorbing microRNAs (miRNAs). We aimed to discover a novel regulatory axis in colorectal cancer (CRC) and p…
View article: Trend of the polyp and adenoma detection rate by sex and age in asymptomatic average-risk and high-risk individuals undergoing screening colonoscopy, 2012–2019
Trend of the polyp and adenoma detection rate by sex and age in asymptomatic average-risk and high-risk individuals undergoing screening colonoscopy, 2012–2019 Open
View article: CRC-ICM: Colorectal Cancer Immune Cell Markers Pattern Dataset
CRC-ICM: Colorectal Cancer Immune Cell Markers Pattern Dataset Open
Colorectal Cancer (CRC) is the second most common cause of cancer death in the world, ad can be identified by the location of the primary tumor in the large intestine: right and left colon, and rectum. Based on the location, CRC shows diff…
View article: Parabens preferentially accumulate in metastatic breast tumors compared to benign breast tumors and the association of breast cancer risk factors with paraben accumulation
Parabens preferentially accumulate in metastatic breast tumors compared to benign breast tumors and the association of breast cancer risk factors with paraben accumulation Open
Parabens are a category of antimicrobial preservatives that may play a role in the etiology and epidemiology of cancers. Parabens are employed in a wide range of pharmaceuticals, cosmetics, personal care products, and processed foods. Para…
View article: Constructing Novel ceRNA Networks on MiR-616-3p Reveals LncRNAs as Potential Colorectal Cancer Prognostic Biomarkers
Constructing Novel ceRNA Networks on MiR-616-3p Reveals LncRNAs as Potential Colorectal Cancer Prognostic Biomarkers Open
Background. Long noncoding RNAs (lncRNAs) perform as competing endogenous RNAs (ceRNAs) to sponge microRNAs (miRNAs) lead to the advancement of cancer. In this work, we attempted to identify possible long noncoding RNA biomarkers as well a…
View article: Constructing a novel competing Endogenous RNAs network based on NR3C1 and X-linked inhibitor of apoptosis protein genes reveals potential prognostic biomarkers in colorectal cancer
Constructing a novel competing Endogenous RNAs network based on NR3C1 and X-linked inhibitor of apoptosis protein genes reveals potential prognostic biomarkers in colorectal cancer Open
Background: Long noncoding RNAs (lncRNAs) have been recognized as the main modulatory molecules in various cancers and perform as competing endogenous RNAs (ceRNAs). The nuclear hormone receptor superfamily of ligand-activated transcriptio…
View article: High claudin-4 antigen expression in triple-negative breast cancer by the immunohistochemistry method
High claudin-4 antigen expression in triple-negative breast cancer by the immunohistochemistry method Open
Background: Triple-negative breast cancer is a heterogeneous subtype of breast cancer. Claudin is an epithelial tight junctional protein, and also it is a receptor for clostridium perfringens enterotoxin and shows impairment of expression …
View article: Androgen Receptor Expression and Its Correlation with Clinicopathological Parameters in Iranian Patients with Triple Negative Breast Cancer
Androgen Receptor Expression and Its Correlation with Clinicopathological Parameters in Iranian Patients with Triple Negative Breast Cancer Open
BACKGROUND & OBJECTIVE: Our knowledge about correlation of androgen receptor expression and clinicopathological properties of triple-negative breast cancer (TNBC) patients is inadequate, particularly in the Iranian population. The main aim…
View article: A histopathological image dataset for grading breast invasive ductal carcinomas
A histopathological image dataset for grading breast invasive ductal carcinomas Open
Breast cancer is a common cancer in women, and one of the major causes of death among women around the world. Invasive ductal carcinoma (IDC) is the most widespread type of breast cancer with about 80% of all diagnosed cases. Early accurat…