Eli I. Lev
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View article: The effect of national stress events on the incidence of Takotsubo syndrome
The effect of national stress events on the incidence of Takotsubo syndrome Open
We aimed to analyze whether national level stressful events were associated with an increase the incidence of Takotsubo syndrome. Takotsubo syndrome is an acute reversible heart failure, characterized by transient regional wall abnormality…
View article: Immature Platelets and Platelet Reactivity in Patients with COVID-19
Immature Platelets and Platelet Reactivity in Patients with COVID-19 Open
Coronavirus disease 2019 (COVID-19) is associated with a high incidence of thromboembolic events, both venous and arterial. There are currently no specific clinical or laboratory markers to guide antithrombotic therapy for COVID-19 patient…
View article: Interatrial Shunt Treatment for Heart Failure: The Randomized RELIEVE-HF Trial
Interatrial Shunt Treatment for Heart Failure: The Randomized RELIEVE-HF Trial Open
BACKGROUND: An interatrial shunt may provide an autoregulatory mechanism to decrease left atrial pressure and improve heart failure (HF) symptoms and prognosis. METHODS: Patients with symptomatic HF with any left ventricular ejection fract…
View article: Percutaneous Coronary Interventions Using a Ridaforolimus‐Eluting Stent in Patients at High Bleeding Risk
Percutaneous Coronary Interventions Using a Ridaforolimus‐Eluting Stent in Patients at High Bleeding Risk Open
Background Patients treated with percutaneous coronary intervention are often considered to be at a high bleeding risk (HBR). Drug‐eluting stents have been shown to be superior to bare‐metal stents in patients with HBR, even when patients …
View article: Performance of a novel artificial intelligence software developed to derive coronary fractional flow reserve values from diagnostic angiograms
Performance of a novel artificial intelligence software developed to derive coronary fractional flow reserve values from diagnostic angiograms Open
Background Although invasive measurement of fractional flow reserve (FFR) is recommended to guide revascularization, its routine use is underutilized. Recently, a novel non-invasive software that can instantaneously produce FFR values from…
View article: Inflammatory cytokines differ between patients with high versus low CHA2DS2-VASc scores in sinus rhythm-a possible mechanism for adverse cardiovascular events
Inflammatory cytokines differ between patients with high versus low CHA2DS2-VASc scores in sinus rhythm-a possible mechanism for adverse cardiovascular events Open
Patients in SR with high versus low CHA2DS2-VASc scores have high plasma concentrations of systemic inflammation cytokines. The already proven high levels of sP-selectin, that promotes release of inflammatory cytokines from leukocytes, is …
View article: External applicability of the Effect of ticagrelor on Health Outcomes in diabEtes Mellitus patients Intervention Study (THEMIS) trial: An analysis of patients with diabetes and coronary artery disease in the REduction of Atherothrombosis for Continued Health (REACH) registry
External applicability of the Effect of ticagrelor on Health Outcomes in diabEtes Mellitus patients Intervention Study (THEMIS) trial: An analysis of patients with diabetes and coronary artery disease in the REduction of Atherothrombosis for Continued Health (REACH) registry Open
gov identifier: NCT01991795.
View article: Simultaneous Noninvasive Detection and Therapy of Atherosclerosis Using HDL Coated Gold Nanorods
Simultaneous Noninvasive Detection and Therapy of Atherosclerosis Using HDL Coated Gold Nanorods Open
Cardiovascular disease (CVD) is a major cause of death and disability worldwide. A real need exists in the development of new, improved therapeutic methods for treating CVD, while major advances in nanotechnology have opened new avenues in…
View article: Intravascular leiomyomatosis with cardiac extension: a case report
Intravascular leiomyomatosis with cardiac extension: a case report Open
Background Intravascular leiomyomatosis (IVL) with intracardiac extension is a rare benign tumour seen exclusively in women, characterized by proliferation of uterine smooth muscle cells through the venous circulation into the inferior ven…
View article: Impact of Calcium Channel Blockers on Aspirin Reactivity in Patients With Coronary Artery Disease
Impact of Calcium Channel Blockers on Aspirin Reactivity in Patients With Coronary Artery Disease Open
Purpose : Calcium channel blockers (CCBs) do not reduce the risk of initial or recurrent myocardial infarction (MI) in patients diagnosed with stable coronary artery disease (CAD). The aim of this current study was to evaluate the associat…
View article: Immature platelets in patients with Covid-19: association with disease severity
Immature platelets in patients with Covid-19: association with disease severity Open
Background Coronavirus disease 2019 (Covid-19) is associated with a high incidence of thromboembolic events, both venous and arterial. Currently, there are no clinical or laboratory markers to guide risk-stratification or antithrombotic th…
View article: Issue Information ‐ TOC
Issue Information ‐ TOC Open
Extramedullary myelodysplastic/myeloproliferative neoplasm
View article: Diabetes-Related Factors and the Effects of Ticagrelor Plus Aspirin in the THEMIS and THEMIS-PCI Trials
Diabetes-Related Factors and the Effects of Ticagrelor Plus Aspirin in the THEMIS and THEMIS-PCI Trials Open
BACKGROUND THEMIS (N=19,220) and its pre-specified THEMIS-Percutaneous Coronary Intervention (THEMIS-PCI, N=11,154) sub-analysis showed in individuals with type 2 diabetes mellitus (median duration 10.0 years; HbA1c 7.1%) and stable corona…
View article: Effects of electret coating technology on coronary stent thrombogenicity
Effects of electret coating technology on coronary stent thrombogenicity Open
Stent thrombosis (ST) is a catastrophic event and efforts to reduce its incidence by altering blood-stent interactions are longstanding. A new electret coating technology that produces long-lasting negative charge on stent surface could ma…
View article: Temporal Trends in Prognosis of Patients with Acute Coronary Syndrome Complicated by Ventricular Tachyarrhythmia
Temporal Trends in Prognosis of Patients with Acute Coronary Syndrome Complicated by Ventricular Tachyarrhythmia Open
Objectives: To evaluate clinical characteristics and prognosis of patients presented with ventricular tachyarrhythmia (VTA) during the course of acute coronary syndrome (ACS) and to analyze it according to period of presentation. Backgroun…
View article: Comparison of Immature Platelet Fraction and Factors Associated with Inflammation, Thrombosis and Platelet Reactivity Between Left and Right Atria in Patients with Atrial Fibrillation
Comparison of Immature Platelet Fraction and Factors Associated with Inflammation, Thrombosis and Platelet Reactivity Between Left and Right Atria in Patients with Atrial Fibrillation Open
Patients with AF, especially those with CHA2DS2-VASc≥2, have higher markers of thrombogenicity in RA compared to LA. There was no difference in inflammatory properties between the atria.
View article: Cannabis induced cardiac arrhythmias: a case series
Cannabis induced cardiac arrhythmias: a case series Open
Introduction Cannabis use is known to be associated with significant cardiovascular morbidity. We describe three cases of cannabis-related malignant arrhythmias, who presented to the cardiac department at our institution within the last 2 …
View article: Vascular endothelium function among male carriers of BRCA 1&2 germline mutation
Vascular endothelium function among male carriers of BRCA 1&2 germline mutation Open
Background: Breast cancer susceptibility genes 1&2 (BRCA1&2) mutations hinder DNA-repair. Germline mutations in these genes are known to cause cancer; however, they may have other consequences. In this study we evaluated for the first time…
View article: Dysfunctional endothelial progenitor cells in patients with Hodgkin’s lymphoma in complete remission
Dysfunctional endothelial progenitor cells in patients with Hodgkin’s lymphoma in complete remission Open
Background Patients with a history of Hodgkin's lymphoma (HL) are at increased long‐term risk of cardiovascular morbidity and mortality. Studies report an association between the pathophysiology of coronary artery disease (CAD) and levels …