Elias Hellou
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View article: Assessment of Clinical Significance of Molecular <i>Streptococcus agalactiae</i> Detection in Patients with Suspected Pneumonia
Assessment of Clinical Significance of Molecular <i>Streptococcus agalactiae</i> Detection in Patients with Suspected Pneumonia Open
Background Streptococcus agalactiae (GBS) may cause pneumonia or may colonize the respiratory tract, making its clinical significance uncertain when detected in respiratory specimens. This study aimed to assess whether clinicians interpret…
View article: Reduced Circulating α‐Klotho Levels Are Associated With Elevated Mortality and Arterial Calcifications of Aorta and Iliac Arteries
Reduced Circulating α‐Klotho Levels Are Associated With Elevated Mortality and Arterial Calcifications of Aorta and Iliac Arteries Open
Background α‐Klotho is a multifunctional protein implicated in vascular aging. Declining Klotho levels are associated with arterial stiffness, endothelial dysfunction, and vascular calcification. We investigated the associations between ci…
View article: Endothelial dysfunction as a feature of vascular aging
Endothelial dysfunction as a feature of vascular aging Open
Endothelial dysfunction can be regarded as the earliest feature of vascular aging and may occur in individuals without traditional risk factors for cardiovascular disease. Once present, endothelial dysfunction is known to increase the risk…
View article: Performance of a novel artificial intelligence software developed to derive coronary fractional flow reserve values from diagnostic angiograms
Performance of a novel artificial intelligence software developed to derive coronary fractional flow reserve values from diagnostic angiograms Open
Background Although invasive measurement of fractional flow reserve (FFR) is recommended to guide revascularization, its routine use is underutilized. Recently, a novel non-invasive software that can instantaneously produce FFR values from…
View article: Monitoring of the lung fluid status in hospitalized COVID-19 patients for predicts outcome. Results of the IMPEDANCE-Corona Trial
Monitoring of the lung fluid status in hospitalized COVID-19 patients for predicts outcome. Results of the IMPEDANCE-Corona Trial Open
Introduction Prediction of the clinical deterioration in hospitalized COVOD-19 patients is an unmet goal. Aim To assess monitoring of lung fluid status of hospitalized COVID-19 patients as a tool to predict clinical respiratory deteriorati…
View article: Effect of ArtemiC in patients with COVID‐19: A Phase II prospective study
Effect of ArtemiC in patients with COVID‐19: A Phase II prospective study Open
Despite intensive efforts, there is no effective remedy for COVID‐19. Moreover, vaccination efficacy declines over time and may be compromised against new SARS‐CoV‐2 lineages. Therefore, there remains an unmet need for simple, accessible, …
View article: First-in-Human Evaluation of the Safety and Efficacy of a Novel Stent Positioning Assistance System for Precise Positioning of Coronary Stents
First-in-Human Evaluation of the Safety and Efficacy of a Novel Stent Positioning Assistance System for Precise Positioning of Coronary Stents Open
Objectives. This study was planned for evaluating the safety and efficacy of SPAS (stent positioning assistance system) device in first-in-human procedures. Background. SPAS is a novel device that can be used for improved positioning of co…
View article: Age is the main determinant of COVID-19 related in-hospital mortality with minimal impact of pre-existing comorbidities, a retrospective cohort study
Age is the main determinant of COVID-19 related in-hospital mortality with minimal impact of pre-existing comorbidities, a retrospective cohort study Open
Background Age and comorbidities increase COVID-19 related in-hospital mortality risk, but the extent by which comorbidities mediate the impact of age remains unknown. Methods In this multicenter retrospective cohort study with data from 4…
View article: Clinical presentation, disease course, and outcome of COVID-19 in hospitalized patients with and without pre-existing cardiac disease: a cohort study across 18 countries
Clinical presentation, disease course, and outcome of COVID-19 in hospitalized patients with and without pre-existing cardiac disease: a cohort study across 18 countries Open
Aims Patients with cardiac disease are considered high risk for poor outcomes following hospitalization with COVID-19. The primary aim of this study was to evaluate heterogeneity in associations between various heart disease subtypes and i…
View article: Modern Stents: Where Are We Going?
Modern Stents: Where Are We Going? Open
Coronary artery stenting is the treatment of choice for patients requiring coronary angioplasty. We describe the major advancements with this technology. There have been significant developments in the design of stents and adjunctive medic…
View article: The impact of comorbidities, sex and age on the occurrence of acute kidney injury among patients undergoing nephron-sparing surgery
The impact of comorbidities, sex and age on the occurrence of acute kidney injury among patients undergoing nephron-sparing surgery Open
Background: The aim of this study was to report the impact of patients’ baseline characteristics on the incidence of acute kidney injury (AKI) after nephron-sparing surgery (NSS) for localized kidney cancer. Patients and methods: Data from…