Élie Sarraf
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View article: The Drug Titration Paradox Updated and Reinterpreted: With Perfect Titration, Dose and Effect Will Be Uncorrelated
The Drug Titration Paradox Updated and Reinterpreted: With Perfect Titration, Dose and Effect Will Be Uncorrelated Open
The drug titration paradox is a clinical observation at a population level whereby patients receiving a high dose of medication appear to have a lower‐than‐average clinical effect, and patients receiving a low dose of medication appear to …
View article: Enhancing Sepsis prognosis: Integrating social determinants and demographic variables into a comprehensive model for critically ill patients
Enhancing Sepsis prognosis: Integrating social determinants and demographic variables into a comprehensive model for critically ill patients Open
Adding patient-specific demographic and socioeconomic information to clinical metrics significantly improves sepsis mortality prediction. This suggests a more comprehensive, multidimensional prognostic approach is needed for accurate sepsi…
View article: Integrating Social Determinants of Health with SOFA Scoring to Enhance Mortality Prediction in Septic Patients: A Multidimensional Prognostic Model
Integrating Social Determinants of Health with SOFA Scoring to Enhance Mortality Prediction in Septic Patients: A Multidimensional Prognostic Model Open
Background The Sequential Organ Failure Assessment (SOFA) score is an established tool for monitoring organ failure and defining sepsis. However, its predictive power for sepsis mortality may not account for the full spectrum of influentia…
View article: Electronic Health Record data is unable to effectively characterize measurement error from pulse oximetry: a simulation study
Electronic Health Record data is unable to effectively characterize measurement error from pulse oximetry: a simulation study Open
Purpose Articles utilizing large data sets from electronic health records (EHR) have been used to demonstrate race-based imprecision in pulse oximetry (SpO2) measurements. These articles do not appear to recognize the impact of the variabi…
View article: The Curse of Dimensionality
The Curse of Dimensionality Open