Elin M. Rees
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View article: Progressive alterations in white matter microstructure across the timecourse of Huntington's disease
Progressive alterations in white matter microstructure across the timecourse of Huntington's disease Open
Background Whole‐brain longitudinal diffusion studies are crucial to examine changes in structural connectivity in neurodegeneration. Here, we investigated the longitudinal alterations in white matter (WM) microstructure across the timecou…
View article: Validating Automated Segmentation Tools in the Assessment of Caudate Atrophy in Huntington’s Disease
Validating Automated Segmentation Tools in the Assessment of Caudate Atrophy in Huntington’s Disease Open
Background: Neuroimaging shows considerable promise in generating sensitive and objective outcome measures for therapeutic trials across a range of neurodegenerative conditions. For volumetric measures the current gold standard is manual d…
View article: Visuospatial Processing Deficits Linked to Posterior Brain Regions in Premanifest and Early Stage Huntington’s Disease
Visuospatial Processing Deficits Linked to Posterior Brain Regions in Premanifest and Early Stage Huntington’s Disease Open
Objectives: Visuospatial processing deficits have been reported in Huntington’s disease (HD). To date, no study has examined associations between visuospatial cognition and posterior brain findings in HD. Methods: We compared 119 premanife…