Eline S. de Klerk
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View article: Longitudinal Respiratory Subphenotypes and Differences in Response to Positive End-Expiratory Pressure and Fio2 Ventilation Strategy in COVID-19 ARDS
Longitudinal Respiratory Subphenotypes and Differences in Response to Positive End-Expiratory Pressure and Fio2 Ventilation Strategy in COVID-19 ARDS Open
Background: In patients with ARDS, positive end-expiratory pressure (PEEP) titration remains a challenge and recommendations are not in agreement. In mechanically ventilated patients with COVID-19, subphenotypes based on different respirat…
View article: Study protocol of the PRINCESS trial—PReoperative INtermittent fasting versus CarbohydratE loading to reduce inSulin resiStance versus standard of care in orthopaedic patients: a randomised controlled trial
Study protocol of the PRINCESS trial—PReoperative INtermittent fasting versus CarbohydratE loading to reduce inSulin resiStance versus standard of care in orthopaedic patients: a randomised controlled trial Open
Introduction Surgical trauma induces a metabolic stress response, resulting in reduced insulin sensitivity and hyperglycaemia. Postoperative insulin resistance (IR) is associated with postoperative complications, and extended preoperative …
View article: Sex Differences in Outcomes After Elective and Acute Aortic Surgery—A Single-Centre Experience over the Last Two Decades
Sex Differences in Outcomes After Elective and Acute Aortic Surgery—A Single-Centre Experience over the Last Two Decades Open
Background/Objectives: Recent studies show conflicting results regarding sex-related differences in outcomes following aortic surgery. This study primarily evaluated 20-year mortality rates, along with 30-day and one- and five-year rates, …
View article: A Comparative Analysis of the Impact of Two Different Cognitive Aid Bundle Designs on Adherence to Best Clinical Practice in Simulated Perioperative Emergencies
A Comparative Analysis of the Impact of Two Different Cognitive Aid Bundle Designs on Adherence to Best Clinical Practice in Simulated Perioperative Emergencies Open
Background: Stress and human error during perioperative emergency situations can significantly impact patient morbidity and mortality. Previous research has shown that cognitive aid bundles (CABs) minimize critical misses by 75%. This stud…
View article: High PEEP/low FiO2 ventilation is associated with lower mortality in COVID–19
High PEEP/low FiO2 ventilation is associated with lower mortality in COVID–19 Open
High PEEP ventilation was associated with improved ICU survival in patients with COVID-ARDS.
View article: Exploring the impact of left ventricular diastolic dysfunction on postoperative cardiac surgery outcomes, with a focus on sex disparities: a comprehensive literature review
Exploring the impact of left ventricular diastolic dysfunction on postoperative cardiac surgery outcomes, with a focus on sex disparities: a comprehensive literature review Open
Introduction Left ventricular diastolic dysfunction (LVDD) is known to cause worse outcomes after cardiac surgery. Females have twice the risk of developing LVDD compared with males. The aim of this literature review was to evaluate the as…
View article: What Really Matters to Survivors of Acute Type A Aortic Dissection—A Survey of Patient-Reported Outcomes in the Dutch National Aortic Dissection Advocacy Group
What Really Matters to Survivors of Acute Type A Aortic Dissection—A Survey of Patient-Reported Outcomes in the Dutch National Aortic Dissection Advocacy Group Open
(1) Background: Type A acute aortic dissection (TAAAD) almost always requires emergency surgery, and postoperative complications are common. Quality assurance systems tend to measure only the hard outcomes, e.g., complications and mortalit…
View article: Reducing postoperative fasting times by implementing a food service in the Post Anaesthesia Care Unit (PACU)
Reducing postoperative fasting times by implementing a food service in the Post Anaesthesia Care Unit (PACU) Open
In a heterogeneous group of adult post-surgical patients with a planned overnight stay in the PACU, implementation of a food service resulted in a significant and clinically relevant reduction of postoperative fasting time, and increased p…
View article: Association between early cumulative fluid balance and successful liberation from invasive ventilation in COVID-19 ARDS patients — insights from the PRoVENT-COVID study: a national, multicenter, observational cohort analysis
Association between early cumulative fluid balance and successful liberation from invasive ventilation in COVID-19 ARDS patients — insights from the PRoVENT-COVID study: a national, multicenter, observational cohort analysis Open
View article: Prognostication using SpO2/FiO2 in invasively ventilated ICU patients with ARDS due to COVID-19 – Insights from the PRoVENT-COVID study
Prognostication using SpO2/FiO2 in invasively ventilated ICU patients with ARDS due to COVID-19 – Insights from the PRoVENT-COVID study Open
View article: Association of intensity of ventilation with 28-day mortality in COVID-19 patients with acute respiratory failure: insights from the PRoVENT-COVID study
Association of intensity of ventilation with 28-day mortality in COVID-19 patients with acute respiratory failure: insights from the PRoVENT-COVID study Open
View article: Mortality associated with early changes in ARDS severity in COVID–19 patients – Insights from the PRoVENT–COVID study
Mortality associated with early changes in ARDS severity in COVID–19 patients – Insights from the PRoVENT–COVID study Open
View article: Ventilation management and clinical outcomes in invasively ventilated patients with COVID-19 (PRoVENT-COVID): a national, multicentre, observational cohort study
Ventilation management and clinical outcomes in invasively ventilated patients with COVID-19 (PRoVENT-COVID): a national, multicentre, observational cohort study Open