Elise Catlin
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View article: Nano-PhotoCrystals (Photosensitive Nanocrystals) of Aloe Emodin Combined with Dissolving Microneedles for Dual Smart Targeting of Acute Bacterial Skin and Soft Tissue Infections
Nano-PhotoCrystals (Photosensitive Nanocrystals) of Aloe Emodin Combined with Dissolving Microneedles for Dual Smart Targeting of Acute Bacterial Skin and Soft Tissue Infections Open
Acute bacterial skin and soft tissue infections (ABSSTIs) are often treated with antibiotics, facing challenges with off-target toxicity and limited tissue penetration, with inadequate treatment escalating into serious conditions requiring…
View article: A dynamic duo comes of age: Nanocrystals and microneedles for hydrophobic drug delivery
A dynamic duo comes of age: Nanocrystals and microneedles for hydrophobic drug delivery Open
NC - MN systems have shown promise in self-administered and long-acting therapies. Yet, stability issues, manufacturing reproducibility, and regulatory uncertainty still remain barriers to translation. Progress in scalable manufacturing an…
View article: A novel temperature-controlled media milling device to produce drug nanocrystals at the laboratory scale
A novel temperature-controlled media milling device to produce drug nanocrystals at the laboratory scale Open
Poor aqueous solubility of preexisting and emerging drug molecules is a common issue faced in the field of pharmaceutics. To address this, particle size reduction techniques, including drug micro- and nanonisation have been widely employed…
View article: Bioadhesive eutectogels supporting drug nanocrystals for long-acting delivery to mucosal tissues
Bioadhesive eutectogels supporting drug nanocrystals for long-acting delivery to mucosal tissues Open
View article: On a highway to the brain: A review on nose-to-brain drug delivery using nanoparticles
On a highway to the brain: A review on nose-to-brain drug delivery using nanoparticles Open
The administration of drugs to the central nervous system (CNS) is primarily controlled by the blood-brain barrier (BBB), a structure that prevents the passage of foreign compounds from the blood to the brain's extracellular fluid. Althoug…