Elise Daems
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View article: Evaluation of an Innovative Portable Heroin Electrochemical Sensor for Empowering Forensic Laboratories
Evaluation of an Innovative Portable Heroin Electrochemical Sensor for Empowering Forensic Laboratories Open
The increasing misuse of opioids in Europe is an alarming trend, leading to severe social and health consequences. Heroin, a highly potent and addictive opioid, remains the main contributor to the health burden associated with opioid use i…
View article: Non-enzymatic isothermal strand displacement and amplification (NISDA) does not enable sensitive nucleic acid quantification
Non-enzymatic isothermal strand displacement and amplification (NISDA) does not enable sensitive nucleic acid quantification Open
Enzyme-free isothermal amplification methods offer a promising alternative to enzymatic assays for nucleic acid detection, particularly in low-resource settings. The nonenzymatic isothermal strand displacement and amplification (NISDA) ass…
View article: Haem-mediated albumin biosensing: Towards voltammetric detection of PFOA
Haem-mediated albumin biosensing: Towards voltammetric detection of PFOA Open
The haem group is a promising redox probe for the design of albumin-based voltammetric sensors. Among the endogenous ligands carried by human serum albumin (hSA), haem is characterised by a reversible redox behaviour and its binding kineti…
View article: Unveiling the binding mode of perfluorooctanoic acid to human serum albumin
Unveiling the binding mode of perfluorooctanoic acid to human serum albumin Open
Perfluorooctanoic acid (PFOA) is a toxic compound that is absorbed and distributed throughout the body by noncovalent binding to serum proteins such as human serum albumin (hSA). Though the interaction between PFOA and hSA has been already…
View article: Native mass spectrometry for the design and selection of protein bioreceptors for perfluorinated compounds
Native mass spectrometry for the design and selection of protein bioreceptors for perfluorinated compounds Open
Native mass spectrometry allows the screening of possible protein bioreceptors for perfluorinated alkyl substances.
Allosteric modulation of the GTPase activity of a bacterial LRRK2 homolog by conformation-specific Nanobodies Open
Mutations in the Parkinson's disease (PD)-associated protein leucine-rich repeat kinase 2 (LRRK2) commonly lead to a reduction of GTPase activity and increase in kinase activity. Therefore, strategies for drug development have mainly been …