Elise Rees
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View article: Single-cell profiling of human bone marrow reveals multiple myeloma progression is accompanied by an increase in CD56<sup>bright</sup>bone marrow resident NK cells
Single-cell profiling of human bone marrow reveals multiple myeloma progression is accompanied by an increase in CD56<sup>bright</sup>bone marrow resident NK cells Open
Natural killer (NK) cells play a key role in the innate immune response against tumour progression. While the immune microenvironment in multiple myeloma (MM) becomes increasingly dysfunctional during disease evolution, little is known abo…
View article: Tumour-intrinsic features shape T-cell differentiation through myeloma disease evolution
Tumour-intrinsic features shape T-cell differentiation through myeloma disease evolution Open
The haematological malignancy multiple myeloma is associated with skewed T-cell activation and function. T-cell alterations are detectable in asymptomatic myeloma precursor conditions and have the potential to identify precursor patients a…
View article: CD200 ectodomain shedding into the tumor microenvironment leads to NK cell dysfunction and apoptosis
CD200 ectodomain shedding into the tumor microenvironment leads to NK cell dysfunction and apoptosis Open
The basis of immune evasion, a hallmark of cancer, can differ even when cancers arise from one cell type such as in the human skin keratinocyte carcinomas: basal and squamous cell carcinoma. Here we showed that the basal cell carcinoma tum…
View article: CNV analysis in a large schizophrenia sample implicates deletions at 16p12.1 and SLC1A1 and duplications at 1p36.33 and CGNL1
CNV analysis in a large schizophrenia sample implicates deletions at 16p12.1 and SLC1A1 and duplications at 1p36.33 and CGNL1 Open
Large and rare copy number variants (CNVs) at several loci have been shown to increase risk for schizophrenia. Aiming to discover novel susceptibility CNV loci, we analyzed 6882 cases and 11 255 controls genotyped on Illumina arrays, most …
View article: Socio-economic drivers of specialist anglers targeting the non-native European catfish (Silurus glanis) in the UK
Socio-economic drivers of specialist anglers targeting the non-native European catfish (Silurus glanis) in the UK Open
Information about the socioeconomic drivers of Silurus glanis anglers in the UK were collected using questionnaires from a cross section of mixed cyprinid fisheries to elucidate human dimensions in angling and non-native fisheries manageme…