Elizabeth Cyarto
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View article: The impact of a multi-component hospital avoidance programme in residential aged care homes: a stepped-wedge cluster randomised trial
The impact of a multi-component hospital avoidance programme in residential aged care homes: a stepped-wedge cluster randomised trial Open
Objectives To investigate if a multi-component hospital avoidance intervention would reduce hospital bed days in residential aged care (RAC) homes. Design Prospective stepped-wedge cluster randomised trial with usual care and intervention …
View article: Implementing an intervention to facilitate early detection of deterioration in aged care residents: Process evaluation of the EDDIE+ trial
Implementing an intervention to facilitate early detection of deterioration in aged care residents: Process evaluation of the EDDIE+ trial Open
Background: EDDIE + was a stepped wedge cluster randomised controlled trial with an embedded process evaluation in 11 residential aged care (RAC) homes in Queensland, Australia. The intervention aimed to upskill RAC staff to identify and m…
View article: Effects of physical activity on depressive symptoms in older caregivers: The IMPACCT randomized controlled trial
Effects of physical activity on depressive symptoms in older caregivers: The IMPACCT randomized controlled trial Open
Objectives Physical activity (PA) can reduce depressive symptoms but has not been tested amongst depressed older caregivers and their care‐recipients. The aim of this single‐blind randomized controlled trial was to investigate the effect o…
View article: 3T sodium-MRI as predictor of neurocognition in nondemented older adults: a cross sectional study
3T sodium-MRI as predictor of neurocognition in nondemented older adults: a cross sectional study Open
Dementia is a burgeoning global problem. Novel magnetic resonance imaging (MRI) metrics beyond volumetry may bring new insight and aid clinical trial evaluation of interventions early in the Alzheimer’s disease course to complement existin…
View article: From pilot to a multi-site trial: refining the Early Detection of Deterioration in Elderly Residents (EDDIE +) intervention
From pilot to a multi-site trial: refining the Early Detection of Deterioration in Elderly Residents (EDDIE +) intervention Open
View article: From pilot to a multi-site trial: Refining the Early Detection of Deterioration in Elderly Residents (EDDIE+) intervention
From pilot to a multi-site trial: Refining the Early Detection of Deterioration in Elderly Residents (EDDIE+) intervention Open
Background Early Detection of Deterioration in Elderly Residents (EDDIE+) is a multi-modal intervention focused on empowering nursing and personal care workers to identify and proactively manage deterioration of residents living in residen…
View article: Australian retirement village residents: wellbeing profiles and factors associated with low wellbeing
Australian retirement village residents: wellbeing profiles and factors associated with low wellbeing Open
The characteristics of Australian retirement village residents, an under-researched population, are not well understood. Knowledge of their wellbeing and modifiable factors associated with low wellbeing would aid in the introduction of hea…
View article: Cycling Without Age: An Australian residential aged care home experience
Cycling Without Age: An Australian residential aged care home experience Open
Objective Cycling Without Age (CWA) involves taking residents on outdoor trishaw (electric bicycle) rides driven by trained ‘pilots’. This study explored the CWA experience from the perspective of residents and family members, staff and vo…
View article: Author Correction: Asymmetric thinning of the cerebral cortex across the adult lifespan is accelerated in Alzheimer’s disease
Author Correction: Asymmetric thinning of the cerebral cortex across the adult lifespan is accelerated in Alzheimer’s disease Open
View article: A codesigned fit‐for‐purpose implementation framework for aged care
A codesigned fit‐for‐purpose implementation framework for aged care Open
Rationale, Aims and Objectives The field of implementation science is critical for embedding research evidence into healthcare practice, benefiting individuals, organizations, governments, and the broader community. Implementation science …
View article: Effectiveness of Peer-Led Wellbeing Interventions in Retirement Living: A Systematic Review
Effectiveness of Peer-Led Wellbeing Interventions in Retirement Living: A Systematic Review Open
Retirement living (RL) communities may be an ideal setting in which to utilize peer-leaders to implement or support health and wellbeing interventions. To date, this literature has not been systematically summarized. The purpose of this st…
View article: A stepped-wedge randomised controlled trial assessing the implementation, effectiveness and cost-consequences of the EDDIE+ hospital avoidance program in 12 residential aged care homes: study protocol
A stepped-wedge randomised controlled trial assessing the implementation, effectiveness and cost-consequences of the EDDIE+ hospital avoidance program in 12 residential aged care homes: study protocol Open
View article: Loneliness in older age: What is it, why is it happening and what should we do about it in Australia?
Loneliness in older age: What is it, why is it happening and what should we do about it in Australia? Open
Loneliness is an important health issue facing older people due to its association with poor quality of life and poor health outcomes. This paper aimed to clarify key issues around loneliness among older adults and draw attention to innova…
View article: Being Your Best: protocol for a feasibility study of a codesigned approach to reduce symptoms of frailty in people aged 65 years or more after transition from hospital
Being Your Best: protocol for a feasibility study of a codesigned approach to reduce symptoms of frailty in people aged 65 years or more after transition from hospital Open
Introduction The population is ageing, with increasing health and supportive care needs. For older people, complex chronic health conditions and frailty can lead to a cascade of repeated hospitalisations and further decline. Existing solut…
View article: Asymmetric thinning of the cerebral cortex across the adult lifespan is accelerated in Alzheimer’s disease
Asymmetric thinning of the cerebral cortex across the adult lifespan is accelerated in Alzheimer’s disease Open
View article: Risk prediction of late-onset Alzheimer’s disease implies an oligogenic architecture
Risk prediction of late-onset Alzheimer’s disease implies an oligogenic architecture Open
View article: Baseline White Matter Is Associated With Physical Fitness Change in Preclinical Alzheimer’s Disease
Baseline White Matter Is Associated With Physical Fitness Change in Preclinical Alzheimer’s Disease Open
White matter (WM) microstructure is a sensitive marker to distinguish individuals at risk of Alzheimer's disease. The association of objective physical fitness (PF) measures and WM microstructure has not been explored and mixed results rep…
View article: Physical activity for older Australians with mild cognitive impairment or subjective cognitive decline – A narrative review to support guideline development
Physical activity for older Australians with mild cognitive impairment or subjective cognitive decline – A narrative review to support guideline development Open
View article: Association Between Cognitive Function and Clustered Cardiovascular Risk of Metabolic Syndrome in Older Adults at Risk of Cognitive Decline
Association Between Cognitive Function and Clustered Cardiovascular Risk of Metabolic Syndrome in Older Adults at Risk of Cognitive Decline Open
View article: Relationship of Established Cardiovascular Risk Factors and Peripheral Biomarkers on Cognitive Function in Adults at Risk of Cognitive Deterioration
Relationship of Established Cardiovascular Risk Factors and Peripheral Biomarkers on Cognitive Function in Adults at Risk of Cognitive Deterioration Open
This study provides evidence to support the associations between vascular risk factors (Framingham scores, fasting glucose, and homocysteine) and poorer cognitive functions. Additionally, we measured several peripheral biomarkers to furthe…
View article: A Randomized Controlled Trial of Adherence to a 24-Month Home-Based Physical Activity Program and the Health Benefits for Older Adults at Risk of Alzheimer’s Disease: The AIBL Active-Study
A Randomized Controlled Trial of Adherence to a 24-Month Home-Based Physical Activity Program and the Health Benefits for Older Adults at Risk of Alzheimer’s Disease: The AIBL Active-Study Open
Background: Previous studies have demonstrated that physical activity (PA) interventions can improve physical and cognitive outcomes in older adults, but most have been relatively short in duration (<1 year) with a few having specifically …
View article: National Physical Activity Guidelines for older Australians with Mild Cognitive Impairment and Subjective Cognitive Decline
National Physical Activity Guidelines for older Australians with Mild Cognitive Impairment and Subjective Cognitive Decline Open
View article: A blood-based biomarker panel indicates IL-10 and IL-12/23p40 are jointly associated as predictors of β-amyloid load in an AD cohort
A blood-based biomarker panel indicates IL-10 and IL-12/23p40 are jointly associated as predictors of β-amyloid load in an AD cohort Open
View article: A randomized controlled trial of physical activity with individual goal-setting and volunteer mentors to overcome sedentary lifestyle in older adults at risk of cognitive decline: the INDIGO trial protocol
A randomized controlled trial of physical activity with individual goal-setting and volunteer mentors to overcome sedentary lifestyle in older adults at risk of cognitive decline: the INDIGO trial protocol Open
Australia New Zealand Clinical Trials Registry ACTRN12613001181796 . (29/10/2013) retrospectively registered.
View article: An Acute Bout of Exercise Improves the Cognitive Performance of Older Adults
An Acute Bout of Exercise Improves the Cognitive Performance of Older Adults Open
There is evidence that an acute bout of exercise confers cognitive benefits, but it is largely unknown what the optimal mode and duration of exercise is and how cognitive performance changes over time after exercise. We compared the cognit…
View article: Achieving physical activity guideline recommendation in older adults at risk of cognitive deterioration
Achieving physical activity guideline recommendation in older adults at risk of cognitive deterioration Open
Aims: Physical activity (PA) is an emerging protective factoragainst cognitive deterioration. The 150 min a week ofat least moderate intensity activity has been mainstreampublic health recommendation for PA, including for …
View article: Association between cardiovascular risk and cognitive measures among older adults at risk of cognitive decline
Association between cardiovascular risk and cognitive measures among older adults at risk of cognitive decline Open
View article: Active ageing with avatars
Active ageing with avatars Open
In this paper we describe the development and testing of a virtual exercise class for older people delivered in realtime using active gaming technology (Microsoft's Kinect for Xbox 360). Four seniors (women, aged 64-74) participated. Each …
View article: Alterations in dorsal and ventral posterior cingulate connectivity in APOE<i>ε</i>4 carriers at risk of Alzheimer's disease
Alterations in dorsal and ventral posterior cingulate connectivity in APOE<i>ε</i>4 carriers at risk of Alzheimer's disease Open
Background Recent evidence suggests that exercise plays a role in cognition and that the posterior cingulate cortex (PCC) can be divided into dorsal and ventral subregions based on distinct connectivity patterns. Aims To examine the effect…
View article: Semi‐automated hippocampal segmentation in people with cognitive impairment using an age appropriate template for registration
Semi‐automated hippocampal segmentation in people with cognitive impairment using an age appropriate template for registration Open
Background To evaluate a new semi‐automated segmentation method for calculating hippocampal volumes and to compare results with standard software tools in a cohort of people with subjective memory complaints (SMC) and mild cognitive impair…