Elizabeth K. Lucas
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View article: Adición de origanum vulgare en la alimentación de pollos de engorde
Adición de origanum vulgare en la alimentación de pollos de engorde Open
La industria avícola es uno de los sectores con mayor crecimiento a nivel mundial y de la misma manera pasa en Ecuador. En los últimos años se va buscado con mayor énfasis varias alternativas viables al uso de antibióticos promotores de cr…
View article: Sex differences in avoidance behavior and cued threat memory dynamics in mice: Interactions between estrous cycle and genetic background
Sex differences in avoidance behavior and cued threat memory dynamics in mice: Interactions between estrous cycle and genetic background Open
View article: Sex differences in avoidance behavior and cued threat memory dynamics in mice: Interactions between estrous cycle and genetic background
Sex differences in avoidance behavior and cued threat memory dynamics in mice: Interactions between estrous cycle and genetic background Open
Anxiety disorders are the most prevalent mental illnesses worldwide, exhibit high heritability, and affect twice as many women as men. To evaluate potential interactions between genetic background and cycling ovarian hormones on sex differ…
View article: Moving beyond descriptive nosology: an argument for negative valence systems disorder
Moving beyond descriptive nosology: an argument for negative valence systems disorder Open
View article: Sex differences in socioemotional behavior and changes in ventral hippocampal transcription across aging in C57Bl/6J mice
Sex differences in socioemotional behavior and changes in ventral hippocampal transcription across aging in C57Bl/6J mice Open
View article: Sex differences in socioemotional behavior and changes in ventral hippocampal transcription across aging in C57Bl/6J mice
Sex differences in socioemotional behavior and changes in ventral hippocampal transcription across aging in C57Bl/6J mice Open
Socioemotional health is positively correlated with improved cognitive and physical aging. Despite known sex differences in socioemotional behaviors and trajectory of aging, the interactive effects between sex and aging on socioemotional o…
View article: Real world safety and exploratory efficacy of gene therapy for patients with 5q-Spinal Muscular Atrophy in a Brazilian cohort
Real world safety and exploratory efficacy of gene therapy for patients with 5q-Spinal Muscular Atrophy in a Brazilian cohort Open
Spinal muscular atrophy (SMA) is a motor neuron disease associated with progressive muscle weakness, ventilatory failure, and reduced survival. Onasemnogene abeparvoves is the first gene replacement therapy (GT) approved to treat this cond…
View article: Sex-Specific Neural Networks of Cued Threat Conditioning: A Pilot Study
Sex-Specific Neural Networks of Cued Threat Conditioning: A Pilot Study Open
Cued threat conditioning is the most common preclinical model for emotional memory, which is dysregulated in anxiety disorders and post-traumatic stress disorder. Though women are twice as likely as men to develop these disorders, current …
View article: Orexin signaling in GABAergic lateral habenula neurons modulates aggressive behavior in male mice
Orexin signaling in GABAergic lateral habenula neurons modulates aggressive behavior in male mice Open
View article: S189. PREFRONTAL PARVALBUMIN INTERNEURONS REQUIRE JUVENILE SOCIAL EXPERIENCE TO ESTABLISH ADULT SOCIAL BEHAVIOR
S189. PREFRONTAL PARVALBUMIN INTERNEURONS REQUIRE JUVENILE SOCIAL EXPERIENCE TO ESTABLISH ADULT SOCIAL BEHAVIOR Open
Background Social isolation during developmental critical windows could be highly detrimental to proper functioning of mature prefrontal cortex (PFC) and establishment of appropriate adult behaviors. However, the specific circuits that und…
View article: Prefrontal parvalbumin interneurons require juvenile social experience to establish adult social behavior
Prefrontal parvalbumin interneurons require juvenile social experience to establish adult social behavior Open
View article: Orexin signaling in GABAergic lateral habenula neurons modulates aggressive behavior
Orexin signaling in GABAergic lateral habenula neurons modulates aggressive behavior Open
Heightened aggression is characteristic of multiple neuropsychiatric disorders and can have a wide variety of negative effects on patients, their families, and the public. Recent studies in humans and animals have implicated brain reward c…
View article: GABAergic interneurons: The orchestra or the conductor in fear learning and memory?
GABAergic interneurons: The orchestra or the conductor in fear learning and memory? Open
View article: Multimodal and Site-Specific Plasticity of Amygdala Parvalbumin Interneurons after Fear Learning
Multimodal and Site-Specific Plasticity of Amygdala Parvalbumin Interneurons after Fear Learning Open
View article: Cortical PGC-1α-Dependent Transcripts Are Reduced in Postmortem Tissue From Patients With Schizophrenia
Cortical PGC-1α-Dependent Transcripts Are Reduced in Postmortem Tissue From Patients With Schizophrenia Open
The transcriptional coactivator peroxisome proliferator-activated receptor-gamma coactivator 1-alpha (PGC-1α) has been linked to multiple neurological and psychiatric disorders including schizophrenia, but its involvement in the pathophysi…
View article: Interneuron Transcriptional Dysregulation Causes Frequency-Dependent Alterations in the Balance of Inhibition and Excitation in Hippocampus
Interneuron Transcriptional Dysregulation Causes Frequency-Dependent Alterations in the Balance of Inhibition and Excitation in Hippocampus Open
Circuit dysfunction in complex brain disorders such as schizophrenia and autism is caused by imbalances between inhibitory and excitatory synaptic transmission (I/E). Short-term plasticity differentially alters responses from excitatory an…
View article: Cerebellar transcriptional alterations with Purkinje cell dysfunction and loss in mice lacking PGC-1α
Cerebellar transcriptional alterations with Purkinje cell dysfunction and loss in mice lacking PGC-1α Open
Alterations in the expression and activity of the transcriptional coactivator peroxisome proliferator-activated receptor γ coactivator-1α (ppargc1a or PGC-1α) have been reported in multiple movement disorders, yet it is unclear how a lack …