Explanipedia

Review of a high-resourced cancer-related fatigue clinic and considerations in lower-resourced environments Open

C. P. Escalante, Lucy Potter, Angella Bassaragh, Ellen F. Manzullo · 2025

Cancer-related fatigue (CRF) is a frequent symptom in cancer patients and is often difficult to manage. In our highly resourced comprehensive cancer center, we developed a clinic in 1998 to evaluate and manage patients with CRF. In this pa…

15 years supporting adherence to oral anti-cancer treatment: use of the MASCC Oral Agent Teaching Tool (MOATT) worldwide, a review for the future Open

Sultan Kav, Mapi Fleury, Paz Fernández‐Ortega, Ellen F. Manzullo, Kimberley‐Ann Kerr , et al. · 2025

Introduction The MASCC Oral Agent Teaching Tool (MOATT®) was developed to address the challenges of patient education and adherence in the context of oral anticancer agents. Despite its evidence-based design and global availability, there …

A Qualitative Study of the Knowledge of Metabolic Syndrome, Attitudes about Lifestyle Modifications, and Preferences for Lifestyle Interventions among Patients with Cancer and Metabolic Syndrome Open

Isabel Martinez Leal, Ashwathy Balachandran Pillai, Jessica T. Foreman, Kimberly Siu, Natalia I. Heredia , et al. · 2024

Metabolic syndrome is a group of disorders—hypertension, dyslipidemia, obesity, and insulin resistance—that together increase the risk of coronary heart disease, stroke, and diabetes. Although ~60% of cancer patients have metabolic syndrom…

The Impact of Immunotherapy on Sleep and Circadian Rhythms in Patients with Cancer Open

Diwakar D. Balachandran, Lara Bashoura, Ajay Sheshadri, Ellen F. Manzullo, Saadia A. Faiz · 2023

Immunotherapy has revolutionized treatments for both early and advanced cancers, and as their role evolves, their impact on sleep and circadian rhythms continues to unfold. The recognition, evaluation, and treatment of sleep and circadian …

A Qualitative Study of Knowledge of Metabolic Syndrome, Attitudes about Lifestyle Modifications, and Preferences for Lifestyle Interventions among Patients with Cancer and Metabolic Syndrome Open

Isabel Martinez Leal, Ashwathy Balachandran Pillai, Jessica T. Foreman, Kimberly W. Siu, Natalia I. Heredia , et al. · 2023

Background Nearly 60% of patients with cancer have metabolic syndrome, which increases the risk of mortality, but there is no clear guidance for oncology providers about its management. Here, we report on the qualitative component of a lar…

Characteristics of Cancer-Related Fatigue and Concomitant Sleep Disturbance in Cancer Patients Open

Ivan H. C. Wu, Diwakar D. Balachandran, Saadia A. Faiz, Lara Bashoura, Carmen P. Escalante , et al. · 2021

A central role for apathy in the effectiveness of interventions for <span>cancer‐related</span> fatigue Open

Tamara E. Lacourt, Cobi J. Heijnen, Ellen F. Manzullo, Carmen P. Escalante · 2020

Objective Cancer‐related fatigue (CRF) affects a substantial number of cancer patients and survivors. Recommendations for CRF treatments are largely based on results of randomized controlled trials. The interpretability of such results is …

An effort expenditure perspective on cancer-related fatigue Open

Tamara E. Lacourt, Elisabeth G. Vichaya, Carmen P. Escalante, Ellen F. Manzullo, G. Brandon Gunn , et al. · 2018

Cancer-related fatigue presenting with excessive daytime sleepiness Open

Diwakar D. Balachandran, Saadia A. Faiz, Lara Bashoura, Ellen F. Manzullo · 2017

Cancer-related fatigue is a common symptom in cancer patients which commonly occurs in relation to sleep disturbance. We report a case of a 35-year-old breast cancer survivor, in whom polysomnography and multiple sleep latency testing were…

High-Dose Asian Ginseng (Panax Ginseng) for Cancer-Related Fatigue Open

Sriram Yennurajalingam, Akhila Reddy, Nizar M. Tannir, Gary B. Chisholm, Richard T. Lee , et al. · 2015

Introduction and Objective. Cancer-related fatigue (CRF) is the most common and severe symptom in patients with cancer. The number and efficacy of available treatments for CRF are limited. The objective of this preliminary study was to ass…

A Randomized, Double-blind, 2-Period, Placebo-Controlled Crossover Trial of a Sustained-Release Methylphenidate in the Treatment of Fatigue in Cancer Patients Open

Carmen P. Escalante, Christina Meyers, James M. Reuben, Xuemei Wang, Wei Qiao , et al. · 2014

Low-dose methylphenidate did not improve cancer-related fatigue. Patients taking methylphenidate had better cognition and were able to work more hours. Patients tolerated methylphenidate well, and the majority felt better and wanted to con…

Cancer-Related Fatigue: The Approach and Treatment Open

Carmen P. Escalante, Ellen F. Manzullo · 2009

SLEEP DISORDERS IN PATIENTS WITH CANCER-RELATED FATIGUE Open

Diwakar D. Balachandran, Lara Bashoura, Saadia A. Faiz, Brenda Aaron-Remmert, M. A. Kallen , et al. · 2009

Fatigue and Its Risk Factors in Cancer Patients Who Seek Emergency Care Open

Carmen P. Escalante, Ellen F. Manzullo, Tony Lam, Joe Ensor, Rosalie Valdres , et al. · 2008

Once daily, oral, outpatient quinolone monotherapy for low‐risk cancer patients with fever and neutropenia Open

Kenneth V. I. Rolston, Ellen F. Manzullo, Linda S. Elting, Susan Frisbee‐Hume, Leslie W. McMahon , et al. · 2006

BACKGROUND The objective of this study was to assess the feasibility of empiric, oral, outpatient quinolone monotherapy in 40 adult patients with fever and neutropenia who were at low risk for serious medical complications. METHODS Patient…

The burdens of cancer therapy Open

Linda S. Elting, Catherine D. Cooksley, Mark S. Chambers, Scott B. Cantor, Ellen F. Manzullo , et al. · 2003

BACKGROUND Mucositis is a common but poorly studied problem among patients with solid tumors. The authors examined the clinical and economic outcomes of oral and gastrointestinal (GI) mucositis among patients receiving myelosuppressive che…

A Cancer-Related Fatigue Clinic: Opportunities and Challenges Open

Carmen P. Escalante, Ellen F. Manzullo, Rosalie Valdres · 2003

Cancer-related fatigue (CRF) is the most prevalent symptom of cancer, occurring in 60% to 90% of patients and surpassing pain in frequency. CRF may increase patients' anxieties and hamper their quality of life. We developed a CRF clinic in…

Mississippi mud in the 1990s Open

Linda S. Elting, Edward Rubenstein, Danna Kurtin, Kenneth V. I. Rolston, John Taffou Fangtang , et al. · 1998

Vancomycin-associated toxicities usually are mild and self-limiting. Some patients are at a significantly higher risk of nephrotoxicity but the authors believe these individuals can be identified reliably with the Nephrotoxicity Risk Index…

The Generalist Finds a Niche in a Comprehensive Cancer Center: A Decade of Growth at the University of Texas M.D. Anderson Cancer Center Open

Carmen P. Escalante, Ellen F. Manzullo, Mary Ann Weiser, Edward Rubenstein · 1998

Outpatient treatment of febrile episodes in low-risk neutropenic patients with cancer Open

Edward Rubenstein, Kenneth V. I. Rolston, Carmen P. Escalante, Ellen F. Manzullo, Pamela Hughes , et al. · 1993

This prospective study suggested that outpatient antibiotic therapy for febrile episodes in low-risk neutropenic patients with cancer is safe and effective. Better oral regimens are needed.

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