Ellen F. Perkowski
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View article: Erratum for Perkowski et al., “The EXIT Strategy: an Approach for Identifying Bacterial Proteins Exported during Host Infection”
Erratum for Perkowski et al., “The EXIT Strategy: an Approach for Identifying Bacterial Proteins Exported during Host Infection” Open
Erratum for “The EXIT Strategy: an Approach for Identifying Bacterial Proteins Exported during Host Infection”
View article: Tat–Dependent Translocation of an F420–Binding Protein of Mycobacterium tuberculosis
Tat–Dependent Translocation of an F420–Binding Protein of Mycobacterium tuberculosis Open
F420 is a unique cofactor present in a restricted range of microorganisms, including mycobacteria. It has been proposed that F420 has an important role in the oxidoreductive reactions of Mycobacterium tuberculosis, possibly associated with…
View article: Reversible acetylation regulates acetate and propionate metabolism in Mycobacterium smegmatis
Reversible acetylation regulates acetate and propionate metabolism in Mycobacterium smegmatis Open
Carbon metabolic pathways are important to the pathogenesis of Mycobacterium tuberculosis, the causative agent of tuberculosis. However, extremely little is known about metabolic regulation in mycobacteria. There is growing evidence for ly…
View article: Identification of a Lactate-Quinone Oxidoreductase in Staphylococcus aureus that is Essential for Virulence
Identification of a Lactate-Quinone Oxidoreductase in Staphylococcus aureus that is Essential for Virulence Open
Staphylococcus aureus is an important human pathogen commonly infecting nearly every host tissue. The ability of S. aureus to resist innate immunity is critical to its success as a pathogen, including its propensity to grow in the presence…
View article: An orphaned Mce-associated membrane protein of M ycobacterium tuberculosis is a virulence factor that stabilizes Mce transporters: OmamA functions in virulence and Mce stability
An orphaned Mce-associated membrane protein of M ycobacterium tuberculosis is a virulence factor that stabilizes Mce transporters: OmamA functions in virulence and Mce stability Open
Mycobacterium tuberculosis proteins that are exported out of the bacterial cytoplasm are ideally positioned to be virulence factors; however, the functions of individual exported proteins remain largely unknown. Previous studies identified…
View article: Development of a Novel Method for Genome-wide Identification of Proteins Exported during Infection and Functional Studies of One in vivo Exported Protein in Mycobacterium tuberculosis
Development of a Novel Method for Genome-wide Identification of Proteins Exported during Infection and Functional Studies of One in vivo Exported Protein in Mycobacterium tuberculosis Open
Intracellular pathogens manipulate and outwit the host’s immune defenses and reprogram the hostile intracellular environment into a hospitable replicative niche. The intracellular pathogen Mycobacterium tuberculosis is responsible for the …
View article: The EXIT Strategy: an Approach for Identifying Bacterial Proteins Exported during Host Infection
The EXIT Strategy: an Approach for Identifying Bacterial Proteins Exported during Host Infection Open
Exported proteins of bacterial pathogens function both in essential physiological processes and in virulence. Past efforts to identify exported proteins were limited by the use of bacteria growing under laboratory ( in vitro ) conditions. …
View article: Genome Sequences of Diverse Human Cytomegalovirus Strains with Utility in Drug Screening and Vaccine Evaluation
Genome Sequences of Diverse Human Cytomegalovirus Strains with Utility in Drug Screening and Vaccine Evaluation Open
Cytomegalovirus displays genetic heterogeneity, which has implications for antiviral and vaccine development. Many studies have focused on laboratory isolates that have been extensively adapted for growth on fibroblasts. Here, we report wh…
View article: An orphaned <scp>M</scp>ce‐associated membrane protein of <scp><i>M</i></scp><i>ycobacterium tuberculosis</i> is a virulence factor that stabilizes <scp>M</scp>ce transporters
An orphaned <span>M</span>ce‐associated membrane protein of <span><i>M</i></span><i>ycobacterium tuberculosis</i> is a virulence factor that stabilizes <span>M</span>ce transporters Open
Summary Mycobacterium tuberculosis proteins that are exported out of the bacterial cytoplasm are ideally positioned to be virulence factors; however, the functions of individual exported proteins remain largely unknown. Previous studies id…