Ellen Kuhl
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View article: A Complement to Neural Networks for Anisotropic Inelasticity at Finite Strains (Source code and data)
A Complement to Neural Networks for Anisotropic Inelasticity at Finite Strains (Source code and data) Open
This repository accompanies the work “A Complement to Neural Networks for Anisotropic Inelasticity at Finite Strains”. It contains the complete implementation of the neural network–based constitutive modeling framework presented in the pap…
View article: Stretching the Limits: From Planar-Biaxial Stress–Stretch to Arterial Pressure–Diameter
Stretching the Limits: From Planar-Biaxial Stress–Stretch to Arterial Pressure–Diameter Open
Understanding the physiological condition of the vascular system is critical to explain, treat, and manage vascular disease. Numerous experimental and computational studies characterize the mechanical behavior of arterial tissue under cont…
View article: Shape-Space Graphs: Fast and Collision-Free Path Planning for Soft Robots
Shape-Space Graphs: Fast and Collision-Free Path Planning for Soft Robots Open
Soft robots, inspired by elephant trunks or octopus arms, offer extraordinary flexibility to bend, twist, and elongate in ways that rigid robots cannot. However, their motion planning remains a challenge, especially in cluttered environmen…
View article: Autoencoder-based non-intrusive model order reduction in continuum mechanics
Autoencoder-based non-intrusive model order reduction in continuum mechanics Open
We propose a non-intrusive, Autoencoder-based framework for reduced-order modeling in continuum mechanics. Our method integrates three stages: (i) an unsupervised Autoencoder compresses high-dimensional finite element solutions into a comp…
View article: Discovering dispersion: How robust is automated model discovery for human myocardial tissue?
Discovering dispersion: How robust is automated model discovery for human myocardial tissue? Open
Computational modeling has become an integral tool for understanding the interaction between structural organization and functional behavior in a wide range of biological tissues, including the human myocardium. Traditional constitutive mo…
View article: Stretching the Limits: From Planar-Biaxial Stress–Stretch to Arterial Pressure–Diameter
Stretching the Limits: From Planar-Biaxial Stress–Stretch to Arterial Pressure–Diameter Open
Understanding the physiological condition of the vascular system is critical to explain, treat, and manage vascular disease. Numerous experimental and computational studies characterize the mechanical behavior of arterial tissue under cont…
View article: Probing mycelium mechanics and taste: The moist and fibrous signature of fungi steak
Probing mycelium mechanics and taste: The moist and fibrous signature of fungi steak Open
Fungi-based meat is emerging as a promising class of nutritious, sustainable, and minimally processed biomaterials with the potential to complement or replace traditional animal and plant-based meats. However, its mechanical and sensory pr…
View article: Medical digital twins: enabling precision medicine and medical artificial intelligence
Medical digital twins: enabling precision medicine and medical artificial intelligence Open
The notion of medical digital twins is gaining popularity both within the scientific community and among the general public; however, much of the recent enthusiasm has occurred in the absence of a consensus on their fundamental make-up. Di…
View article: AI for food: accelerating and democratizing discovery and innovation
AI for food: accelerating and democratizing discovery and innovation Open
By 2050, feeding nearly 10 billion people will require transformative changes to ensure nutritious, sustainable food for all. Our current food system is inefficient and unsustainable. Traditional attempts to transform the global food syste…
View article: Discovering dispersion: How robust is automated model discovery for human myocardial tissue?
Discovering dispersion: How robust is automated model discovery for human myocardial tissue? Open
Computational modeling has become an integral tool for understanding the interaction between structural organization and functional behavior in a wide range of biological tissues, including the human myocardium. Traditional constitutive mo…
View article: Probing mycelium mechanics and taste: The moist and fibrous signature of fungi steak
Probing mycelium mechanics and taste: The moist and fibrous signature of fungi steak Open
Fungi-based meat is emerging as a promising class of nutritious, sustainable, and minimally processed biomaterials with the potential to complement or replace traditional animal and plant-based meats. However, its mechanical and sensory pr…
View article: Atrial constitutive neural networks
Atrial constitutive neural networks Open
This work presents a novel approach for characterizing the mechanical behavior of atrial tissue using constitutive neural networks. Based on experimental biaxial tensile test data of healthy human atria, we automatically discover the most …
View article: Biaxial testing and sensory texture evaluation of plant-based and animal deli meat
Biaxial testing and sensory texture evaluation of plant-based and animal deli meat Open
Animal agriculture is one of the largest contributors to global carbon emissions. Plant-based meats offer a sustainable alternative to animal meat; yet, people are reluctant to switch their diets and spending habits, in large due to the ta…
View article: Characterizing variability in passive myocardial stiffness in healthy human left ventricles using personalized MRI and finite element modeling
Characterizing variability in passive myocardial stiffness in healthy human left ventricles using personalized MRI and finite element modeling Open
Abnormal passive stiffness of the heart muscle (myocardium) is evident in the pathophysiology of several cardiovascular diseases, making it an important indicator of heart health. Recent advancements in cardiac imaging and biophysical mode…
View article: Automated model discovery for tensional homeostasis: Constitutive machine learning in growth and remodeling
Automated model discovery for tensional homeostasis: Constitutive machine learning in growth and remodeling Open
We present a built-in physics neural network architecture, known as inelastic Constitutive Artificial Neural Network (iCANN), to discover the inelastic phenomenon of tensional homeostasis. In this course, identifying the optimal model and …
View article: The mechanical and sensory signature of plant-based and animal meat
The mechanical and sensory signature of plant-based and animal meat Open
Eating less meat is associated with a healthier body and planet. Yet, we remain reluctant to switch to a plant-based diet, largely due to the sensory experience of plant-based meat. Food scientists characterize meat using a double compress…
View article: Two for tau: Automated model discovery reveals two-stage tau aggregation dynamics in Alzheimer’s disease
Two for tau: Automated model discovery reveals two-stage tau aggregation dynamics in Alzheimer’s disease Open
Alzheimer’s disease is a neurodegenerative disorder characterized by the presence of amyloid-β plaques and the accumulation of misfolded tau proteins and neurofibrillary tangles in the brain. A thorough understanding of the local accumulat…
View article: Constitutive neural networks for main pulmonary arteries: Discovering the undiscovered
Constitutive neural networks for main pulmonary arteries: Discovering the undiscovered Open
Accurate modeling of cardiovascular tissues is crucial for understanding and predicting their behavior in various physiological and pathological conditions. In this study, we specifically focus on the pulmonary artery in the context of the…
View article: Mimicking Mechanics: A Comparison of Meat and Meat Analogs
Mimicking Mechanics: A Comparison of Meat and Meat Analogs Open
The texture of meat is one of the most important features to mimic when developing meat analogs. Both protein source and processing method impact the texture of the final product. We can distinguish three types of mechanical tests to quant…
View article: Machine learning reveals correlations between brain age and mechanics
Machine learning reveals correlations between brain age and mechanics Open
Our brain undergoes significant micro- and macroscopic changes throughout its life cycle. It is therefore crucial to understand the effect of aging on the mechanical properties of the brain in order to develop accurate personalized simulat…
View article: Ultra-fast physics-based modeling of the elephant trunk
Ultra-fast physics-based modeling of the elephant trunk Open
With more than 90,000 muscle fascicles, the elephant trunk is a complex biological structure and the largest known muscular hydrostat. It achieves an unprecedented control through intricately orchestrated contractions of a wide variety of …