Ellen Rafferty
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View article: Eligibility for Nirmatrelvir/Ritonavir Among Adults With an Acute Care <scp>COVID</scp> ‐19 Encounter: A Retrospective Cohort Study From Alberta, Canada
Eligibility for Nirmatrelvir/Ritonavir Among Adults With an Acute Care <span>COVID</span> ‐19 Encounter: A Retrospective Cohort Study From Alberta, Canada Open
Purpose To describe the characteristics of adults who had a severe coronavirus disease 2019 (COVID‐19) outcome during a timeframe that nirmatrelvir/ritonavir (NMV‐r; Paxlovid) was available, to assess medical eligibility and receipt of NMV…
View article: The decision uncertainty toolkit: Risk measures and visual outputs to support decision making during public health crises
The decision uncertainty toolkit: Risk measures and visual outputs to support decision making during public health crises Open
Background During public health crises such as the COVID-19 pandemic, decision-makers relied on infectious disease models to evaluate policy options. Often, there is a high degree of uncertainty in the evidence base underpinning these mode…
View article: Cost-effectiveness of RSVpreF vaccine and nirsevimab for the prevention of respiratory syncytial virus disease in Canadian infants
Cost-effectiveness of RSVpreF vaccine and nirsevimab for the prevention of respiratory syncytial virus disease in Canadian infants Open
Prophylactic interventions can substantially reduce RSV disease in infants, and more focused nirsevimab programs are the most cost-effective option at current product prices.
View article: Optimization of an adult immunization program in Canada
Optimization of an adult immunization program in Canada Open
Background Provincial decisions to fund a new immunization program are generally made on a case-by-case basis, without systematic consideration of how the new immunization program may fit within the larger provincial immunization portfolio…
View article: Sex Differences in the Immunogenicity and Efficacy of Seasonal Influenza Vaccines: A Meta-analysis of Randomized Controlled Trials
Sex Differences in the Immunogenicity and Efficacy of Seasonal Influenza Vaccines: A Meta-analysis of Randomized Controlled Trials Open
Background Sex impacts individuals’ response to vaccination. However, most vaccine studies do not report these differences disaggregated by sex. The aim of this study was to assess sex differences in the immunogenicity and efficacy of infl…
View article: Cost-effectiveness of RSVpreF vaccine and nirsevimab for the prevention of respiratory syncytial virus disease in Canadian infants
Cost-effectiveness of RSVpreF vaccine and nirsevimab for the prevention of respiratory syncytial virus disease in Canadian infants Open
Background Health Canada recently authorized the RSVpreF pregnancy vaccine and nirsevimab to protect infants against respiratory syncytial virus (RSV) disease. Objective Assess the cost-effectiveness of RSVpreF and nirsevimab programs in p…
View article: Estimating the Incidence and Economic Cost of Lyme Disease Cases in Canada in the 21st Century with Projected Climate Change
Estimating the Incidence and Economic Cost of Lyme Disease Cases in Canada in the 21st Century with Projected Climate Change Open
Future incidence and economic costs of LD in Canada are likely to be substantial, but uncertainties remain. Because densely populated areas of Canada are projected to become endemic under conservative climate change scenarios, mitigation o…
View article: Healthcare costs and effects of post-COVID-19 condition in Canada
Healthcare costs and effects of post-COVID-19 condition in Canada Open
This article demonstrates the large potential health and economic burden of PCC for Canadians, and the importance of vaccination and other infection control strategies in reducing the longer-term costs and effects.
View article: “I sold my towel and shoes to pay the traditional healer”: Care-seeking costs and productivity losses among snakebite victims in Eastern Province, Rwanda
“I sold my towel and shoes to pay the traditional healer”: Care-seeking costs and productivity losses among snakebite victims in Eastern Province, Rwanda Open
Snakebite envenomation (SBE) is endemic to sub-Saharan Africa and generally over-represented in rural, remote, and impoverished agricultural communities. While poverty is an established risk factor, little research has been done to investi…
View article: Sex differences in adverse events following seasonal influenza vaccines: a meta-analysis of randomised controlled trials
Sex differences in adverse events following seasonal influenza vaccines: a meta-analysis of randomised controlled trials Open
Background Despite being a vaccine-preventable disease, influenza remains a major public health threat with vaccine safety concerns reducing vaccine acceptability. Immune responses to vaccines and adverse events may differ between males an…
View article: Quantifying the economic gains associated with COVID-19 vaccination in the Canadian population: A cost-benefit analysis
Quantifying the economic gains associated with COVID-19 vaccination in the Canadian population: A cost-benefit analysis Open
Our model-based economic evaluation provides a retrospective assessment of COVID-19 vaccination during the first 16 months of the program in Canada and suggests that it was welfare-improving, considering the decreased hospitalizations and …
View article: Using Health Economics to Inform Immunization Policy Across All Levels of Government
Using Health Economics to Inform Immunization Policy Across All Levels of Government Open
Publicly funded immunization programs have grown in both complexity and scope, resulting in increased costs and more complex programmatic decision making. Economic evaluations can provide crucial information to support informed decision ma…
View article: Evaluating the Individual Healthcare Costs and Burden of Disease Associated with RSV Across Age Groups
Evaluating the Individual Healthcare Costs and Burden of Disease Associated with RSV Across Age Groups Open
RSV is a common and expensive infection at the extremes of life, and the development of immunization programs targeting older and younger ages may be important for the reduction of RSV burden and cost.
View article: Impact of the COVID-19 pandemic on vaccine coverage for early childhood vaccines in Alberta, Canada: a population-based retrospective cohort study
Impact of the COVID-19 pandemic on vaccine coverage for early childhood vaccines in Alberta, Canada: a population-based retrospective cohort study Open
Objective To assess the impact of the COVID-19 pandemic on early childhood vaccination coverage in Alberta, Canada. Setting Alberta, a western Canadian province, which has a population of 4.4 million and approximately 50 000 births annuall…
View article: Additional file 2 of Economic evaluation of COVID-19 rapid antigen screening programs in the workplace
Additional file 2 of Economic evaluation of COVID-19 rapid antigen screening programs in the workplace Open
Additional file 2. Details of costs.
View article: COVID-19 pandemic impact on childhood vaccination coverage in Quebec, Canada
COVID-19 pandemic impact on childhood vaccination coverage in Quebec, Canada Open
Response measures to mitigate the coronavirus disease 2019 pandemic impacted access to routine vaccination services. We evaluate the impact of the pandemic on routine infant vaccination uptake by comparing vaccination coverage, vaccine del…
View article: COVID-19 infection among international travellers: a prospective analysis
COVID-19 infection among international travellers: a prospective analysis Open
Objectives This report estimates the risk of COVID-19 importation and secondary transmission associated with a modified quarantine programme in Canada. Design and participants Prospective analysis of international asymptomatic travellers e…
View article: A Net Benefit Approach for the Optimal Allocation of a COVID-19 Vaccine
A Net Benefit Approach for the Optimal Allocation of a COVID-19 Vaccine Open
OBJECTIVE We implement a model-based approach to identify the optimal allocation of a COVID-19 vaccine in the province of Alberta, Canada. METHODS We develop an epidemiologic model to evaluate allocation strategies defined by age and risk …
View article: Equity for health delivery: Opportunity costs and benefits among Community Health Workers in Rwanda
Equity for health delivery: Opportunity costs and benefits among Community Health Workers in Rwanda Open
Community Health Workers (CHWs) play a vital role delivering health services to vulnerable populations in low resource settings. In Rwanda, CHWs provide village-level care focused on maternal/child health, control of infectious diseases, a…
View article: Measurement of coverage, compliance and determinants of uptake in a publicly funded rotavirus vaccination programme: a retrospective cohort study
Measurement of coverage, compliance and determinants of uptake in a publicly funded rotavirus vaccination programme: a retrospective cohort study Open
Objectives In June 2015, Alberta, Canada instituted a universal publicly funded rotavirus vaccination programme (Rotarix, RV1), with vaccine doses scheduled for 2 and 4 months of age. Vaccination was restricted so that infants were only al…
View article: Response to: Costs and savings associated with a pharmacists prescribing for minor ailments program in Saskatchewan
Response to: Costs and savings associated with a pharmacists prescribing for minor ailments program in Saskatchewan Open
We thank the author of the letter for reading and drawing attention to our work.We think that our knowledge and understanding of any issue is advanced by actually producing research that stimulates discussion and debate, and the author of …