Ellen Underwood
YOU?
Author Swipe
View article: General anesthesia in early infancy accelerates visual cortical development
General anesthesia in early infancy accelerates visual cortical development Open
How human brain function is established through protracted trajectories of development is not yet fully understood. Maturation of γ-aminobutyric acid (GABA) circuits drives critical periods of cortical development in animal models. Whether…
View article: Neurodevelopment at 10 months and 2–3 years old after early and prolonged anaesthesia in infancy: General Anaesthesia & Brain Activity study (GABA) secondary analysis
Neurodevelopment at 10 months and 2–3 years old after early and prolonged anaesthesia in infancy: General Anaesthesia & Brain Activity study (GABA) secondary analysis Open
View article: Neurodevelopment of children exposed to prolonged anesthesia in infancy: GABA study interim analysis of resting-state brain networks at 2, 4, and 10-months old
Neurodevelopment of children exposed to prolonged anesthesia in infancy: GABA study interim analysis of resting-state brain networks at 2, 4, and 10-months old Open
We could not demonstrate significant impact of general anesthesia in the first months of life on early development of resting state brain networks over the first postnatal year. Future studies will explore these networks as these infants g…
View article: Significant Incidental Findings in the National Lung Screening Trial
Significant Incidental Findings in the National Lung Screening Trial Open
Importance Low-dose computed tomography (LDCT) lung screening has been shown to reduce lung cancer mortality. Significant incidental findings (SIFs) have been widely reported in patients undergoing LDCT lung screening. However, the exact n…
View article: Tactile sensitivity and motor coordination in infancy: Effect of age, prior surgery, anaesthesia & critical illness
Tactile sensitivity and motor coordination in infancy: Effect of age, prior surgery, anaesthesia & critical illness Open
Background Tactile sensitivity in the infant period is poorly characterized, particularly among children with prior surgery, anaesthesia or critical illness. The study aims were to investigate tactile sensitivity of the foot and the associ…
View article: Tactile sensitivity and motor coordination in infancy - RAW DATA
Tactile sensitivity and motor coordination in infancy - RAW DATA Open
Mechanical stimuli using von Frey hair monofilaments were applied to the foot at graded innocuous and noxious intensities in human infants at Boston Chidren's Hospital, Boston USA. Outcome measures were tactile and nociceptive threshold (l…
View article: Visual-Evoked Potential (VEP) Event-Related Files from the General Anesthesia and Brain Activity (GABA) Study
Visual-Evoked Potential (VEP) Event-Related Files from the General Anesthesia and Brain Activity (GABA) Study Open
HAPPE+ER software was optimized for developmental data using a subset of EEG files from 4-month and 10-month old infants in the General Anesthesia and Brain Activity (GABA) Study. While medically necessary, 1-2 million infants each year un…
View article: Visual-Evoked Potential (VEP) Event-Related Files from the General Anesthesia and Brain Activity (GABA) Study and Infant Sibling Project (ISP)
Visual-Evoked Potential (VEP) Event-Related Files from the General Anesthesia and Brain Activity (GABA) Study and Infant Sibling Project (ISP) Open
HAPPE+ER software was optimized for developmental data using a subset of EEG files from 4-month and 10-month old infants in the General Anesthesia and Brain Activity (GABA) Study. While medically necessary, 1-2 million infants each year un…
View article: Visual-Evoked Potential (VEP) Event-Related Files from the General Anesthesia and Brain Activity (GABA) Study and Infant Sibling Project (ISP)
Visual-Evoked Potential (VEP) Event-Related Files from the General Anesthesia and Brain Activity (GABA) Study and Infant Sibling Project (ISP) Open
HAPPE+ER software was optimized for developmental data using a subset of EEG files from 4-month and 10-month old infants in the General Anesthesia and Brain Activity (GABA) Study. While medically necessary, 1-2 million infants each year un…
View article: Newly Diagnosed Atrial Fibrillation After Transient Ischemic Attack Versus Minor Ischemic Stroke in the POINT Trial
Newly Diagnosed Atrial Fibrillation After Transient Ischemic Attack Versus Minor Ischemic Stroke in the POINT Trial Open
Background Atrial fibrillation/flutter (AF) after transient ischemic attack (TIA) has not been well studied. We compared the likelihood of new AF diagnosis after ischemic stroke versus TIA. Methods and Results The POINT (Platelet‐Oriented …
View article: Patterns of benzodiazepine underdosing in the Established Status Epilepticus Treatment Trial
Patterns of benzodiazepine underdosing in the Established Status Epilepticus Treatment Trial Open
Objective This study was undertaken to describe patterns of benzodiazepine use as first‐line treatment of status epilepticus (SE) and test the association of benzodiazepine doses with response to second‐line agents in patients enrolled in …
View article: Spine surgeon perceptions of the challenges and benefits of telemedicine: an international study
Spine surgeon perceptions of the challenges and benefits of telemedicine: an international study Open
View article: Electroencephalographic Seizures in Emergency Department Patients After Treatment for Convulsive Status Epilepticus
Electroencephalographic Seizures in Emergency Department Patients After Treatment for Convulsive Status Epilepticus Open
Purpose: It is unknown how often and how early EEG is obtained in patients presenting with status epilepticus. The Established Status Epilepticus Treatment Trial enrolled patients with benzodiazepine-refractory seizures and randomized part…
View article: Neurophysiological Assessment of Prolonged Recovery From Neuromuscular Blockade in the Neonatal Intensive Care Unit
Neurophysiological Assessment of Prolonged Recovery From Neuromuscular Blockade in the Neonatal Intensive Care Unit Open
Objective: To evaluate recovery from neuromuscular blockade in infants using Train-of-Four nerve stimulation. Study Design: Ulnar nerve stimulation was used to evoke thumb twitch and reported as Train-of-Four ratio. Thumb twi…
View article: Efficacy of levetiracetam, fosphenytoin, and valproate for established status epilepticus by age group (ESETT): a double-blind, responsive-adaptive, randomised controlled trial
Efficacy of levetiracetam, fosphenytoin, and valproate for established status epilepticus by age group (ESETT): a double-blind, responsive-adaptive, randomised controlled trial Open