Elly Poretsky
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View article: A multifunctional sesquiterpene synthase integrates with cytochrome P450s to reinforce the terpenoid defense network in maize
A multifunctional sesquiterpene synthase integrates with cytochrome P450s to reinforce the terpenoid defense network in maize Open
SUMMARY Terpenoids, the largest and most structurally diverse class of plant natural products, play essential roles in maize defense and ecological interactions. In this study, we identified and functionally characterized a sesquiterpenoid…
View article: Structural Variability of Pfam Domains Based on Alphafold2 Predictions
Structural Variability of Pfam Domains Based on Alphafold2 Predictions Open
Understanding the biological functions of proteins is one of the main goals of functional genomics. Such understanding will help control and manipulate biological processes to enhance desirable traits, including improved abiotic and biotic…
View article: Assessing the performance of generative artificial intelligence in retrieving information against manually curated genetic and genomic data
Assessing the performance of generative artificial intelligence in retrieving information against manually curated genetic and genomic data Open
Curated resources at centralized repositories provide high-value service to users by enhancing data veracity. Curation, however, comes with a cost, as it requires dedicated time and effort from personnel with deep domain knowledge. In this…
View article: Harnessing the predicted maize pan-interactome for putative gene function prediction and prioritization of candidate genes for important traits
Harnessing the predicted maize pan-interactome for putative gene function prediction and prioritization of candidate genes for important traits Open
The recent assembly and annotation of the 26 maize nested association mapping population founder inbreds have enabled large-scale pan-genomic comparative studies. These studies have expanded our understanding of agronomically important tra…
View article: PhosBoost: Improved phosphorylation prediction recall using gradient boosting and protein language models
PhosBoost: Improved phosphorylation prediction recall using gradient boosting and protein language models Open
Protein phosphorylation is a dynamic and reversible post‐translational modification that regulates a variety of essential biological processes. The regulatory role of phosphorylation in cellular signaling pathways, protein–protein interact…
View article: Maize Terpene Synthase 8 (ZmTPS8) Contributes to a Complex Blend of Fungal-Elicited Antibiotics
Maize Terpene Synthase 8 (ZmTPS8) Contributes to a Complex Blend of Fungal-Elicited Antibiotics Open
In maize (Zea mays), fungal-elicited immune responses include the accumulation of terpene synthase (TPS) and cytochrome P450 monooxygenases (CYP) enzymes resulting in complex antibiotic arrays of sesquiterpenoids and diterpenoids, includin…
View article: Shielding the oil reserves: the scutellum as a source of chemical defenses
Shielding the oil reserves: the scutellum as a source of chemical defenses Open
The cereal scutellum is a hub for diverse specialized defense metabolism and pathway discovery.
View article: Comparative analyses of responses to exogenous and endogenous antiherbivore elicitors enable a forward genetics approach to identify maize gene candidates mediating sensitivity to herbivore‐associated molecular patterns
Comparative analyses of responses to exogenous and endogenous antiherbivore elicitors enable a forward genetics approach to identify maize gene candidates mediating sensitivity to herbivore‐associated molecular patterns Open
SUMMARY Crop damage by herbivorous insects remains a significant contributor to annual yield reductions. Following attack, maize ( Zea mays ) responds to herbivore‐associated molecular patterns (HAMPs) and damage‐associated molecular patte…
View article: Peer Review #2 of "MutRank: an R shiny web-application for exploratory targeted mutual rank-based coexpression analyses integrated with user-provided supporting information (v0.1)"
Peer Review #2 of "MutRank: an R shiny web-application for exploratory targeted mutual rank-based coexpression analyses integrated with user-provided supporting information (v0.1)" Open
The rapid assignment of genotypes to phenotypes has been a historically challenging process.The discovery of genes encoding biosynthetic pathway enzymes for defined plant specialized metabolites has been informed and accelerated by the det…
View article: MutRank: an R shiny web-application for exploratory targeted mutual rank-based coexpression analyses integrated with user-provided supporting information
MutRank: an R shiny web-application for exploratory targeted mutual rank-based coexpression analyses integrated with user-provided supporting information Open
The rapid assignment of genotypes to phenotypes has been a historically challenging process. The discovery of genes encoding biosynthetic pathway enzymes for defined plant specialized metabolites has been informed and accelerated by the de…
View article: Differential activities of maize plant elicitor peptides as mediators of immune signaling and herbivore resistance
Differential activities of maize plant elicitor peptides as mediators of immune signaling and herbivore resistance Open
SUMMARY Plant elicitor peptides (Peps) are conserved regulators of defense responses and models for the study of damage‐associated molecular pattern‐induced immunity. Although present as multigene families in most species, the functional r…
View article: Dynamic regulation of Pep-induced immunity through post-translational control of defence transcript splicing
Dynamic regulation of Pep-induced immunity through post-translational control of defence transcript splicing Open
View article: Genetic elucidation of complex biochemical traits mediating maize innate immunity
Genetic elucidation of complex biochemical traits mediating maize innate immunity Open
Specialized metabolites constitute key layers of immunity underlying crop resistance; however, challenges in resolving complex pathways limit our understanding of their functions and applications. In maize ( Zea mays ) the inducible accumu…
View article: Dynamic regulation of immunity through post-translational control of defense transcript splicing
Dynamic regulation of immunity through post-translational control of defense transcript splicing Open
Survival of all living organisms requires the ability to detect attack and swiftly counter with protective immune responses. Despite considerable mechanistic advances, interconnectivity of signaling circuits often remains unclear. A newly-…
View article: Strategies for Network GWAS Evaluated Using Classroom Crowd Science
Strategies for Network GWAS Evaluated Using Classroom Crowd Science Open
View article: Correction: Calcium specificity signaling mechanisms in abscisic acid signal transduction in Arabidopsis guard cells
Correction: Calcium specificity signaling mechanisms in abscisic acid signal transduction in Arabidopsis guard cells Open
A central question is how specificity in cellular responses to the eukaryotic second messenger Ca2+ is achieved. Plant guard cells, that form stomatal pores for gas exchange, provide a powerful system for in depth investigation …
View article: Calcium specificity signaling mechanisms in abscisic acid signal transduction in Arabidopsis guard cells
Calcium specificity signaling mechanisms in abscisic acid signal transduction in Arabidopsis guard cells Open
A central question is how specificity in cellular responses to the eukaryotic second messenger Ca2+ is achieved. Plant guard cells, that form stomatal pores for gas exchange, provide a powerful system for in depth investigation of Ca2+-sig…