Emad Singer
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View article: Initial management and disposition of metastatic spinal cord compression in the emergency department: a review of the literature
Initial management and disposition of metastatic spinal cord compression in the emergency department: a review of the literature Open
For patients with MSCC, early and effective evaluation and intervention in the emergency department, through a coordinated multidisciplinary effort, are vital to optimizing patient outcomes.
View article: DEPDC5 mutations in familial epilepsy syndrome: genetic insights and therapeutic approaches
DEPDC5 mutations in familial epilepsy syndrome: genetic insights and therapeutic approaches Open
Background . DEPDC5 (disheveled, Egl-10 and pleckstrin domain-containing protein 5) familial epilepsy syndrome is a group of epilepsy disorders caused by mutations in DEPDC5 gene, which is a part of the gap activity towards rag 1 (GATOR1) …
View article: Assessing the value of computed tomography (CT) of the chest in the follow-up of patients with intrahepatic cholangiocarcinoma
Assessing the value of computed tomography (CT) of the chest in the follow-up of patients with intrahepatic cholangiocarcinoma Open
The use of short-interval chest CT for surveillance in IHCCA has limited utility, particularly in patients with disease-free abdominal studies.
View article: Brain Metastasis in the Emergency Department: Epidemiology, Presentation, Investigations, and Management
Brain Metastasis in the Emergency Department: Epidemiology, Presentation, Investigations, and Management Open
Brain metastases (BMs) are the most prevalent type of cerebral tumor, significantly affecting survival. In adults, lung cancer, breast cancer, and melanoma are the primary cancers associated with BMs. Symptoms often result from brain compr…
View article: Renal bleeding: imaging and interventions in patients with tumors
Renal bleeding: imaging and interventions in patients with tumors Open
In patients with cancer, spontaneous renal bleeding can stem from a range of underlying factors, necessitating precise diagnostic tools for effective patient management. Benign and malignant renal tumors are among the primary culprits, wit…
View article: Roles of molecular neuroimaging techniques in Parkinsonism
Roles of molecular neuroimaging techniques in Parkinsonism Open
Parkinson's disease affects millions worldwide and is characterized by alpha-synuclein accumulation and loss of dopaminergic neurons in the brain. Until now, there is no cure for Parkinson's disease, and the existing treatments aim to alle…
View article: Hemoptysis in Cancer Patients
Hemoptysis in Cancer Patients Open
Hemoptysis in cancer patients can occur for various reasons, including infections, tumors, blood vessel abnormalities and inflammatory conditions. The degree of hemoptysis is commonly classified according to the quantity of blood expelled.…
View article: Diagnosis and Management of Marchiafava-Bignami Disease, a Rare Neurological Complication of Long-term Alcohol Abuse
Diagnosis and Management of Marchiafava-Bignami Disease, a Rare Neurological Complication of Long-term Alcohol Abuse Open
Marchiafava Bignami disease (MBD) is a neurological disorder characterized by myelin degeneration and tissue necrosis within the central nervous system. This condition predominantly afflicts individuals with chronic alcohol abuse and malnu…
View article: Cutaneous T-cell Lymphoma and Pruritus: The Expression of IL-31 and its Receptors in the Skin
Cutaneous T-cell Lymphoma and Pruritus: The Expression of IL-31 and its Receptors in the Skin Open
Approximately 88% of cutaneous T-cell lymphoma (CTCL) patients are affected by pruritus that responds poorly to current antipruritic therapies. Interleukin (IL)-31, a Th2 cytokine, has been found to be increased in the serum of CTCL patien…