Eman Gharra
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HLA-E[pHLA-G] complex–specific monoclonal antibody enhancing NK activity in multiple myeloma Open
HLA-E presenting the HLA-G leader peptide VMAPRTLFL (HLA-E[pHLA-G]) on tumor cells plays a crucial role in suppressing natural killer (NK) and cytotoxic CD8+ T cells through NKG2A interaction. While blocking HLA-E:NKG2A is a promising immu…