Emanuel Dorbath
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View article: Contact Cluster Modeling of Allosteric Communication in PDZ Domains
Contact Cluster Modeling of Allosteric Communication in PDZ Domains Open
Allostery, the intriguing phenomenon of long-range communication between distant sites in proteins, plays a central role in biomolecular regulation and signal transduction. While it is commonly attributed to conformational rearrangements, …
View article: Universal structure in the relaxation of photoactive proteins
Universal structure in the relaxation of photoactive proteins Open
The nonequilibrium relaxation of a series of, in part, very different photoactive proteins is compared, ranging over up to eleven decades in time. The series comprises various PDZ domains and MCL 1/peptide complexes with artificial azobenz…
View article: Allosteric communication mediated by protein contact clusters: A dynamical model
Allosteric communication mediated by protein contact clusters: A dynamical model Open
Allostery refers to the puzzling phenomenon of long-range communication between distant sites in proteins. Despite its importance in biomolecular regulation and signal transduction, the underlying dynamical process is not well understood. …
View article: Log-periodic oscillations as real-time signatures of hierarchical dynamics in proteins
Log-periodic oscillations as real-time signatures of hierarchical dynamics in proteins Open
The time-dependent relaxation of a dynamical system may exhibit a power-law behavior that is superimposed by log-periodic oscillations. D. Sornette [Phys. Rep. 297, 239 (1998)] showed that this behavior can be explained by a discrete scale…
View article: Log-periodic oscillations as real-time signatures of hierarchical dynamics in proteins
Log-periodic oscillations as real-time signatures of hierarchical dynamics in proteins Open
The time-dependent relaxation of a dynamical system may exhibit a power-law behavior that is superimposed by log-periodic oscillations. Sornette [Phys. Rep. 297, 239 (1998)] showed that this behavior can be explained by a discrete scale in…