Emilie Cadart
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View article: O-GlcNAcylation of fatty acid synthase is required for its proper subcellular localization, expression level, and activity
O-GlcNAcylation of fatty acid synthase is required for its proper subcellular localization, expression level, and activity Open
Fatty Acid Synthase (FASN) is involved in various fundamental cellular processes through its pivotal role in producing fatty acids through the de novo lipogenesis pathway. FASN is frequently overexpressed in tumors and participates in canc…
View article: Heparan Sulfate 3-O-Sulfotransferase 3B1 (HS3ST3B1) Is Associated with Invasive and Mesenchymal-Like Phenotype in Breast Cancer Cells and Promotes Chemo-Resistance through Activation of PDGF-Rβ Pathway
Heparan Sulfate 3-O-Sulfotransferase 3B1 (HS3ST3B1) Is Associated with Invasive and Mesenchymal-Like Phenotype in Breast Cancer Cells and Promotes Chemo-Resistance through Activation of PDGF-Rβ Pathway Open
Alteration in heparan sulfate (HS) biosynthesis has been described to impact a range of pivotal processes involved in cancer progression. HS 3-O-sulfotransferase 3B1 (HS3ST3B1) catalyzes the reaction of 3-O-sulfation within HS chains. Over…