Emilie Lameignère
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View article: Polyphosphate is a novel cofactor for regulation of complement by a serpin, C1 inhibitor
Polyphosphate is a novel cofactor for regulation of complement by a serpin, C1 inhibitor Open
Key Points PolyP, like heparin, is a physiologic cofactor for the C1-INH:C1s interaction, and thus a key negative regulator of complement. Colocalization of polyP with C1-INH in activated platelets suggests that its cofactor function is ph…