Emily N. C. Manoogian
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View article: Post-intervention sustainability of time-restricted eating versus caloric restriction: a secondary analysis
Post-intervention sustainability of time-restricted eating versus caloric restriction: a secondary analysis Open
Rising obesity rates necessitate sustainable weight management strategies. Current lifestyle guidelines focus on reducing caloric intake through personalized interventions to promote compliance. This secondary analysis evaluated post-inter…
View article: The diversity and consistency of what and when people eat
The diversity and consistency of what and when people eat Open
The timing and types of food people eat, along with daily fluctuations in in these parameters, are important factors influencing health and well-being. However, there is limited data on how eating patterns remain consistent over multiple d…
View article: Biological vs. Chronological Overnight Fasting: Influence of Last Evening Meal on Morning Glucose in Dysglycemia
Biological vs. Chronological Overnight Fasting: Influence of Last Evening Meal on Morning Glucose in Dysglycemia Open
Background/Objectives: Nocturnal glucose regulation is a critical but underexplored determinant of next-day fasting glucose (FG), particularly in individuals with dysglycemia. This study examined the role of glucose levels after the last e…
View article: Time-Restricted Eating Improves Quality of Life, Heart Rate, and Mitochondrial Function in Patients with Postural Orthostatic Tachycardia Syndrome
Time-Restricted Eating Improves Quality of Life, Heart Rate, and Mitochondrial Function in Patients with Postural Orthostatic Tachycardia Syndrome Open
Postural orthostatic tachycardia syndrome (POTS) is characterized by an abnormal increase in heart rate upon standing, leading to symptoms such as dizziness, fatigue, and rapid heart rate. Time-restricted eating (TRE), which limits caloric…
View article: Advancing Chrononutrition for Cardiometabolic Health: A 2023 National Heart, Lung, and Blood Institute Workshop Report
Advancing Chrononutrition for Cardiometabolic Health: A 2023 National Heart, Lung, and Blood Institute Workshop Report Open
The circadian system maintains optimal biological functions at the appropriate time of day, and the disruption of this organization can contribute to the pathogenesis of cardiometabolic disorders. The timing of eating is a prominent extern…
View article: Comparing the effectiveness of calorie restriction with and without time-restricted eating on the circadian regulation of metabolism: rationale and protocol of a three-arm randomised controlled trial in adults at risk of type 2 diabetes
Comparing the effectiveness of calorie restriction with and without time-restricted eating on the circadian regulation of metabolism: rationale and protocol of a three-arm randomised controlled trial in adults at risk of type 2 diabetes Open
Time-restricted eating (TRE) may extend the cardiometabolic health benefits of calorie restriction (CR). However, few studies have compared its effect on the circadian regulation of glucose metabolism and the optimal time of day to initiat…
View article: NutriRAG: Unleashing the Power of Large Language Models for Food Identification and Classification through Retrieval Methods
NutriRAG: Unleashing the Power of Large Language Models for Food Identification and Classification through Retrieval Methods Open
Objective This study explores the use of advanced Natural Language Processing (NLP) techniques to enhance food classification and dietary analysis using raw text input from a diet tracking app. Materials and Methods The study was conducted…
View article: Time‐restricted eating, caloric reduction, and unrestricted eating effects on weight and metabolism: a randomized trial
Time‐restricted eating, caloric reduction, and unrestricted eating effects on weight and metabolism: a randomized trial Open
Objective Metabolic improvements may precede weight loss. We compared the effects of self‐selected 8‐h time‐restricted eating (TRE), 15% caloric restriction (CR), and unrestricted eating (UE) on weight, body composition, caloric intake, gl…
View article: Comparing the effectiveness of calorie restriction with and without time-restricted eating on the circadian regulation of metabolism – rationale and protocol of a three-arm randomised controlled trial in adults at risk of type 2 diabetes
Comparing the effectiveness of calorie restriction with and without time-restricted eating on the circadian regulation of metabolism – rationale and protocol of a three-arm randomised controlled trial in adults at risk of type 2 diabetes Open
Background: Time-restricted eating (TRE) may extend the cardiometabolic health benefits of calorie restriction (CR). However, few studies have compared its effect on the circadian regulation of metabolic processes, including glucose metabo…
View article: Late eating is associated with poor glucose tolerance, independent of body weight, fat mass, energy intake and diet composition in prediabetes or early onset type 2 diabetes
Late eating is associated with poor glucose tolerance, independent of body weight, fat mass, energy intake and diet composition in prediabetes or early onset type 2 diabetes Open
This study investigates the impact of habitual late calorie intake on glucose metabolism in adults with overweight or obesity and diet or metformin-controlled prediabetes or type 2 diabetes independently of body weight, fat mass, energy in…
View article: A pre-post trial to examine biological mechanisms of the effects of time-restricted eating on symptoms and quality of life in bipolar disorder
A pre-post trial to examine biological mechanisms of the effects of time-restricted eating on symptoms and quality of life in bipolar disorder Open
Background The primary objective of this trial is to examine the mechanisms of time-restricted eating (TRE) as an adjunct to psychiatric care for people with bipolar disorder (BD) with sleep or circadian disruptions. This study builds on p…
View article: Time-Restricted Eating in Adults With Metabolic Syndrome
Time-Restricted Eating in Adults With Metabolic Syndrome Open
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View article: Feasibility and Cardiometabolic Effects of Time-Restricted Eating in Patients with Metabolic Syndrome
Feasibility and Cardiometabolic Effects of Time-Restricted Eating in Patients with Metabolic Syndrome Open
Metabolic syndrome (MetS) and a prolonged daily eating window (EW) are associated with circadian rhythm disruption and increased cardiometabolic risk. Misalignment between circadian timing system and daily rhythms of food intake adversely …
View article: Diet and Meal Pattern Determinants of Glucose Levels and Variability in Adults with and without Prediabetes or Early-Onset Type 2 Diabetes: A Pilot Study
Diet and Meal Pattern Determinants of Glucose Levels and Variability in Adults with and without Prediabetes or Early-Onset Type 2 Diabetes: A Pilot Study Open
This observational pilot study examined the association between diet, meal pattern and glucose over a 2-week period under free-living conditions in 26 adults with dysglycemia (D-GLYC) and 14 with normoglycemia (N-GLYC). We hypothesized tha…
View article: Neuroendocrine effects of the duper mutation in Syrian hamsters: a role for Cryptochrome 1
Neuroendocrine effects of the duper mutation in Syrian hamsters: a role for Cryptochrome 1 Open
Molecular and physiological determinants of the timing of reproductive events, including the pre-ovulatory LH surge and seasonal fluctuations in fertility, are incompletely understood. We used the Cryptochrome 1 -deficient duper mutant to …
View article: A randomized controlled trial to compare the effects of time-restricted eating vs. Mediterranean diet on symptoms and quality of life in bipolar disorder
A randomized controlled trial to compare the effects of time-restricted eating vs. Mediterranean diet on symptoms and quality of life in bipolar disorder Open
Background: The primary objective of this randomized controlled trial (RCT) is to establish the effectiveness of time-restricted eating (TRE) compared with the Mediterranean diet for people with bipolar disorder (BD) who have symptoms of s…
View article: <scp>Time‐restricted</scp> eating: What we know and where the field is going
<span>Time‐restricted</span> eating: What we know and where the field is going Open
Time-restricted eating (TRE) is a temporal dietary intervention that restricts all dietary intake to a consistent 6- to 11-hour daily eating window with no effort to restrict diet quality or quantity required. TRE is unique in that is one …
View article: Barriers to adherence in time-restricted eating clinical trials: An early preliminary review
Barriers to adherence in time-restricted eating clinical trials: An early preliminary review Open
Time-restricted eating (TRE) has shown potential benefits in optimizing the body's circadian rhythms and improving cardiometabolic health. However, as with all dietary interventions, a participant's ability to adhere to the protocol may be…
View article: Time‐restricted eating did not alter insulin sensitivity or β‐cell function in adults with obesity: A randomized pilot study
Time‐restricted eating did not alter insulin sensitivity or β‐cell function in adults with obesity: A randomized pilot study Open
Objective Decreased insulin sensitivity and impairment of β‐cell function predate and predict development of type 2 diabetes mellitus. Time‐restricted eating (TRE) might have a benefit for these parameters. The objective of this pilot stud…
View article: The impact of a self-selected time restricted eating intervention on eating patterns, sleep, and late-night eating in individuals with obesity
The impact of a self-selected time restricted eating intervention on eating patterns, sleep, and late-night eating in individuals with obesity Open
Background Time restricted eating (TRE), limiting eating to a specific daily window, is a novel dietary intervention, but the mechanisms by which TRE results in weight loss remain unclear. The goal of the current study was to examine chang…
View article: Predicting energy intake with an accelerometer-based intake-balance method
Predicting energy intake with an accelerometer-based intake-balance method Open
Nutritional interventions often rely on subjective assessments of energy intake (EI), but these are susceptible to measurement error. To introduce an accelerometer-based intake-balance method for assessing EI using data from a time-restric…
View article: The effects of time‐restricted eating and weight loss on bone metabolism and health: a 6‐month randomized controlled trial
The effects of time‐restricted eating and weight loss on bone metabolism and health: a 6‐month randomized controlled trial Open
Objective This study explored the impact of time‐restricted eating (TRE) versus standard dietary advice (SDA) on bone health. Methods Adults with ≥1 component of metabolic syndrome were randomized to TRE (ad libitum eating within 12 hours)…