James Henderson
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View article: Identifying, engaging, and supporting care partners in primary care settings: a portal-based intervention
Identifying, engaging, and supporting care partners in primary care settings: a portal-based intervention Open
To our knowledge, this pilot represents the first-of-its-kind effort to identify and support patients with caregiving responsibilities through a portal-based intervention. Our demonstration suggests a simple portal questionnaire, with the …
View article: Use of an Electronic Health Record Order to Directly Refer Patients With Prediabetes to Community-Based Diabetes Prevention Programs
Use of an Electronic Health Record Order to Directly Refer Patients With Prediabetes to Community-Based Diabetes Prevention Programs Open
An eReferral is a promising, scalable strategy to connect patients with prediabetes to community DPPs. Additional strategies are needed to enhance clinicians' use of the eReferral and patients' subsequent program engagement to fully optimi…
View article: First Whole-Genome Assembly of the Galápagos Petrel (<i>Pterodroma phaeopygia</i>) Using Oxford Nanopore Sequencing to Advance Conservation Genomics in a Critically Endangered Seabird
First Whole-Genome Assembly of the Galápagos Petrel (<i>Pterodroma phaeopygia</i>) Using Oxford Nanopore Sequencing to Advance Conservation Genomics in a Critically Endangered Seabird Open
The Galápagos petrel ( Pterodroma phaeopygia ) is a critically endangered procellariiform seabird endemic to the Galápagos Islands. Once abundant, its populations have sharply declined due to invasive predators, habitat degradation, and de…
View article: High-Quality <i>De Novo</i> Genome Assembly for the Galápagos Endemic Lava Gull Using Oxford Nanopore Technologies
High-Quality <i>De Novo</i> Genome Assembly for the Galápagos Endemic Lava Gull Using Oxford Nanopore Technologies Open
High-quality reference genomes permit deeper investigation into species’ evolution and provide insight into species management and conservation. Next-generation sequencing technologies, such as Oxford Nanopore Technologies, allow researche…
View article: Taming the In-Basket—How Two Simple Tools Reduced Portal Message Volume in an Academic Internal Medicine Clinic
Taming the In-Basket—How Two Simple Tools Reduced Portal Message Volume in an Academic Internal Medicine Clinic Open
Background Patient portal messaging has emerged as a critical tool in primary care, particularly during the COVID-19 pandemic, facilitating asynchronous communication between patients and providers. The surge in portal messages during the …
View article: Development, implementation, and evaluation of an intervention to improve multidisciplinary communication about complex patients
Development, implementation, and evaluation of an intervention to improve multidisciplinary communication about complex patients Open
Multidisciplinary team meetings showed promise in enhancing communication, care coordination, and staff satisfaction. Ongoing refinement and assessment are necessary to optimize their feasibility and effectiveness over a longer time period.
View article: Employing Community-Engaged Approaches to Develop and Implement E-Learning for Community Health Workers and Peer Specialists
Employing Community-Engaged Approaches to Develop and Implement E-Learning for Community Health Workers and Peer Specialists Open
Background: New public policies support the growth of the community health worker (CHW) and peer support specialist/peer recovery coach (peer) workforces in health and behavioral health settings. In their roles as a bridge to medical teams…
View article: Statins for the prevention of cirrhosis complications: An American emulation of the StatLiver Trial
Statins for the prevention of cirrhosis complications: An American emulation of the StatLiver Trial Open
View article: Macroscopic label-free biomedical imaging with shortwave infrared Raman scattering
Macroscopic label-free biomedical imaging with shortwave infrared Raman scattering Open
Summary Shortwave infrared (SWIR) imaging provides enhanced tissue penetration and reduced autofluorescence in clinical and pre-clinical applications. However, existing applications often lack the ability to probe chemical composition and …
View article: Implementation of an Enhanced Medication Access Workflow within a Health System Specialty Pharmacy: Impact on Patient & Clinician Experience
Implementation of an Enhanced Medication Access Workflow within a Health System Specialty Pharmacy: Impact on Patient & Clinician Experience Open
Purpose The initiation of specialty medications is associated with patient access challenges and clinician burden. This intervention invested resources upstream of the prescription being written. The evaluation assessed the impact on patie…
View article: A Primary Care–Based Weight Navigation Program
A Primary Care–Based Weight Navigation Program Open
Importance Evidence-based weight management treatments (WMTs) are underused; strategies are needed to increase WMT use and patients' weight loss. Objective To evaluate the association of a primary care–based weight navigation program (WNP)…
View article: Clinical outcomes of female external urine wicking devices as alternatives to indwelling catheters: a systematic review and meta-analysis
Clinical outcomes of female external urine wicking devices as alternatives to indwelling catheters: a systematic review and meta-analysis Open
Background: Female patients using indwelling urinary catheters (IUCs) are disproportionately at risk for developing catheter-associated urinary tract infections (CAUTIs) compared to males. Female external urine wicking devices (FEUWDs) hav…
View article: Genome Assembly of <i>Pyrocephalus nanus</i>: A Step Toward the Genetic Conservation of the Endangered Little Vermilion Flycatcher of the Galapagos Islands
Genome Assembly of <i>Pyrocephalus nanus</i>: A Step Toward the Genetic Conservation of the Endangered Little Vermilion Flycatcher of the Galapagos Islands Open
Incredibly powerful whole genome studies of conservation genetics, evolution, and biogeography become possible for non-model organisms when reference genomes are available. Here, we report the sequence and assembly of the whole genome of t…
View article: High-Quality, Chromosome-Level Reference Genomes of the Viviparous Caribbean Skinks <i>Spondylurus nitidus</i> and <i>S. culebrae</i>
High-Quality, Chromosome-Level Reference Genomes of the Viviparous Caribbean Skinks <i>Spondylurus nitidus</i> and <i>S. culebrae</i> Open
New World mabuyine skinks are a diverse radiation of morphologically cryptic lizards with unique reproductive biologies. Recent studies examining population-level data (morphological, ecological, and genomic) have uncovered novel biodivers…
View article: Weight Loss Treatment and Longitudinal Weight Change Among Primary Care Patients With Obesity
Weight Loss Treatment and Longitudinal Weight Change Among Primary Care Patients With Obesity Open
Importance Among individuals with obesity, 5% or greater weight loss can improve health. Weight management treatments (WMT) include nutrition counseling, very low-calorie meal replacement (MR), antiobesity medications (AOM), and bariatric …
View article: Phylogeny, Population Structure, and Conservation Genomics of Galapagos Vermilion Flycatchers (Genus Pyrocephalus)
Phylogeny, Population Structure, and Conservation Genomics of Galapagos Vermilion Flycatchers (Genus Pyrocephalus) Open
View article: Comparative genomics of symbiotic Photobacterium using highly contiguous genome assemblies from long read sequences
Comparative genomics of symbiotic Photobacterium using highly contiguous genome assemblies from long read sequences Open
This study presents the assembly and comparative genomic analysis of luminous Photobacterium strains isolated from the light organs of 12 fish species using Oxford Nanopore Technologies (ONT) sequencing. The majority of assemblies achieved…
View article: Linear Mixed Model of Virus Disinfection by Chlorine to Harmonize Data Collected Across Broad Environmental Conditions
Linear Mixed Model of Virus Disinfection by Chlorine to Harmonize Data Collected Across Broad Environmental Conditions Open
Despite the critical importance of virus disinfection by chlorine, we lack a fundamental understanding of the relative susceptibility of different viruses to chlorine and robust quantitative relationships between virus disinfection rate co…
View article: Trio‐binned genomes of the woodrats <i>Neotoma bryanti</i> and <i>Neotoma lepida</i> reveal novel gene islands and rapid copy number evolution of xenobiotic metabolizing genes
Trio‐binned genomes of the woodrats <i>Neotoma bryanti</i> and <i>Neotoma lepida</i> reveal novel gene islands and rapid copy number evolution of xenobiotic metabolizing genes Open
The genomic architecture underlying the origins and maintenance of biodiversity is an increasingly accessible feature of species, due in large part to third‐generation sequencing and novel analytical toolsets. Applying these techniques to …
View article: Impact on Health Care Utilization and Costs of a Medicaid Community Health Worker Program in Detroit, 2018–2020: A Randomized Program Evaluation
Impact on Health Care Utilization and Costs of a Medicaid Community Health Worker Program in Detroit, 2018–2020: A Randomized Program Evaluation Open
Objectives. To compare health care utilization and costs between beneficiaries randomly assigned to usual services versus a community health worker (CHW) program implemented by 3 Medicaid health plans. Methods. From February 2018 to June 2…
View article: Type 2 Diabetes Management, Control and Outcomes During the COVID-19 Pandemic in Older US Veterans: an Observational Study
Type 2 Diabetes Management, Control and Outcomes During the COVID-19 Pandemic in Older US Veterans: an Observational Study Open
View article: Integrating oral health into community health worker and peer provider certifications in Michigan: A community action report
Integrating oral health into community health worker and peer provider certifications in Michigan: A community action report Open
Introduction A multi‐disciplinary, community‐university‐government collaboration resulted in the development of Oral Health for Community Workers , a brief, oral health online e‐learning module. The e‐learning module was designed to improv…
View article: Feasibility of a Risk-Based Approach to Cataract Surgery Preoperative Medical Evaluation
Feasibility of a Risk-Based Approach to Cataract Surgery Preoperative Medical Evaluation Open
This study suggests that a virtual, risk-based approach to preoperative medical evaluations for cataract surgery is associated with safe and efficient outcomes. These findings may encourage health care systems and ambulatory surgery center…
View article: The Easter Egg Weevil (Pachyrhynchus) genome reveals syntenic patterns in Coleoptera across 200 million years of evolution
The Easter Egg Weevil (Pachyrhynchus) genome reveals syntenic patterns in Coleoptera across 200 million years of evolution Open
Patterns of genomic architecture across insects remain largely undocumented or decoupled from a broader phylogenetic context. For instance, it is unknown whether translocation rates differ between insect orders. We address broad scale patt…
View article: Patterns and Determinants of Low-Value Preoperative Testing in Michigan
Patterns and Determinants of Low-Value Preoperative Testing in Michigan Open
This cohort study examines use of preoperative testing before 3 low-risk ambulatory surgical procedures across diverse practice settings in Michigan.
View article: Trio-binned genomes of the woodrats<i>Neotoma bryanti</i>and<i>N. lepida</i>reveal novel gene islands and rapid copy number evolution of xenobiotic metabolizing cytochrome p450 genes
Trio-binned genomes of the woodrats<i>Neotoma bryanti</i>and<i>N. lepida</i>reveal novel gene islands and rapid copy number evolution of xenobiotic metabolizing cytochrome p450 genes Open
The genomic architecture underlying the origins and maintenance of biodiversity is an increasingly accessible feature of species, due in large part to third-generation sequencing and novel analytical toolsets. Woodrats of the genus Neotoma…
View article: Antisense oligonucleotides and nucleic acids generate hypersensitive platelets
Antisense oligonucleotides and nucleic acids generate hypersensitive platelets Open
View article: The Easter Egg Weevil (<i>Pachyrhynchus</i>) genome reveals synteny in Coleoptera across 200 million years of evolution
The Easter Egg Weevil (<i>Pachyrhynchus</i>) genome reveals synteny in Coleoptera across 200 million years of evolution Open
Patterns of genomic architecture across insects remain largely undocumented or decoupled from a broader phylogenetic context. For instance, it is unknown whether translocation rates differ between insect orders? We address broad scale patt…
View article: Predictive modeling of virus inactivation by UV
Predictive modeling of virus inactivation by UV Open
Disinfection strategies are commonly applied to inactivate pathogenic viruses in water, food, air, and on surfaces to prevent the spread of infectious diseases. Determining how quickly viruses are inactivated to mitigate health risks is no…
View article: Genomic Characterization and Curation of UCEs Improves Species Tree Reconstruction
Genomic Characterization and Curation of UCEs Improves Species Tree Reconstruction Open
Ultraconserved genomic elements (UCEs) are generally treated as independent loci in phylogenetic analyses. The identification pipeline for UCE probes does not require prior knowledge of genetic identity, only selecting loci that are highly…