Emily G. Pendleton
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View article: Vision-based manipulation of transparent plastic bags in industrial setups
Vision-based manipulation of transparent plastic bags in industrial setups Open
Introduction This paper addresses the challenges of vision-based manipulation for autonomous cutting and unpacking of transparent plastic bags in industrial setups, contributing to the Industry 4.0 paradigm. Industry 4.0, emphasizing data-…
View article: Vision-based Manipulation of Transparent Plastic Bags in Industrial Setups
Vision-based Manipulation of Transparent Plastic Bags in Industrial Setups Open
This paper addresses the challenges of vision-based manipulation for autonomous cutting and unpacking of transparent plastic bags in industrial setups, aligning with the Industry 4.0 paradigm. Industry 4.0, driven by data, connectivity, an…
View article: Spatial polarimetric second harmonic generation evaluation of collagen in a hypophosphatasia mouse model
Spatial polarimetric second harmonic generation evaluation of collagen in a hypophosphatasia mouse model Open
Polarization-resolved second harmonic generation (pSHG) is a label-free method that has been used in a range of tissue types to describe collagen orientation. In this work, we develop pSHG analysis techniques for investigating cranial bone…
View article: Compromised Muscle Properties in a Severe Hypophosphatasia Murine Model
Compromised Muscle Properties in a Severe Hypophosphatasia Murine Model Open
Hypophosphatasia (HPP) is a rare metabolic bone disorder characterized by low levels of tissue non-specific alkaline phosphatase (TNAP) that causes under-mineralization of the bone, leading to bone deformity and fractures. In addition, pat…
View article: Multimodal analysis of the differential effects of cyclic strain on collagen isoform composition, fibril architecture and biomechanics of tissue engineered tendon
Multimodal analysis of the differential effects of cyclic strain on collagen isoform composition, fibril architecture and biomechanics of tissue engineered tendon Open
Tendon is predominantly composed of aligned type I collagen, but additional isoforms are known to influence fibril architecture and maturation, which contribute to the tendon’s overall biomechanical performance. The role of the less well-s…
View article: Nanofiber-Based Delivery of Bioactive Lipids Promotes Pro-regenerative Inflammation and Enhances Muscle Fiber Growth After Volumetric Muscle Loss
Nanofiber-Based Delivery of Bioactive Lipids Promotes Pro-regenerative Inflammation and Enhances Muscle Fiber Growth After Volumetric Muscle Loss Open
Volumetric muscle loss (VML) injuries after extremity trauma results in an important clinical challenge often associated with impaired healing, significant fibrosis, and long-term pain and functional deficits. While acute muscle injuries t…
View article: Spatial frequency metrics for analysis of microscopic images of musculoskeletal tissues
Spatial frequency metrics for analysis of microscopic images of musculoskeletal tissues Open
Purpose: Imaging-based metrics for analysis of biological tissues are powerful tools that can extract information such as shape, size, periodicity, and many other features to assess the requested qualities of a tissue. Muscular and osseous…
View article: Second harmonic generation characterization of collagen in whole bone
Second harmonic generation characterization of collagen in whole bone Open
Bone is a unique biological composite material made up of a highly structured collagen mesh matrix and mineral deposits. Although mineral provides stiffness, collagen’s secondary organization provides a critical role in bone elasticity. He…
View article: Spatial frequency metrics for analysis of microscopic images of musculoskeletal tissues
Spatial frequency metrics for analysis of microscopic images of musculoskeletal tissues Open
Purpose: Imaging-based metrics for analysis of biological tissues are powerful tools that can extract information such as shape, size, periodicity, and many other features to assess the requested qualities of a tissue. Muscular and osseous…
View article: Five-dimensional two-photon volumetric microscopy of in-vivo dynamic activities using liquid lens remote focusing
Five-dimensional two-photon volumetric microscopy of in-vivo dynamic activities using liquid lens remote focusing Open
Multi-photon scanning microscopy provides a robust tool for optical sectioning, which can be used to capture fast biological events such as blood flow, mitochondrial activity, and neuronal action potentials. For many studies, it is importa…
View article: 5D multi-photon volumetric microscopy of in-vivo dynamic activities using liquid lens remote focusing
5D multi-photon volumetric microscopy of in-vivo dynamic activities using liquid lens remote focusing Open
Multi-photon excitation fluorescence scanning microscopy has been proven to be a robust tool for deep tissue monitoring of biological activity. Multi-photon scanning microscopy provides optical sectioning, which can be used to capture fast…
View article: Two-photon deep-tissue spatially resolved mitochondrial imaging using membrane potential fluorescence fluctuations
Two-photon deep-tissue spatially resolved mitochondrial imaging using membrane potential fluorescence fluctuations Open
Cell metabolism and viability are directly reflected in their mitochondria. Imaging-based analysis of mitochondrial morphological structure, size and dynamic characteristics can therefore provide critical insight into cell function. Howeve…