Emily L. Button
YOU?
Author Swipe
Characterization of functionally deficient SIM2 variants found in patients with neurological phenotypes Open
Single-minded 2 (SIM2) is a neuron-enriched basic Helix–Loop–Helix/PER–ARNT–SIM (bHLH/PAS) transcription factor essential for mammalian survival. SIM2 is located within the Down syndrome critical region (DSCR) of chromosome 21, and manipul…