Emily R. Adams
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View article: Comparison of the analytical and clinical sensitivities of 34 rapid antigen tests with prevalent SARS-CoV-2 variants of concern during the COVID-19 pandemic in the UK
Comparison of the analytical and clinical sensitivities of 34 rapid antigen tests with prevalent SARS-CoV-2 variants of concern during the COVID-19 pandemic in the UK Open
Antigen-detection rapid diagnostic tests (Ag-RDTs) have become a central pillar for the management of coronavirus disease worldwide due to their speed and ease of use and are now being developed for use in other emerging outbreaks. Like ot…
View article: Measurement of charged hadron multiplicity in Au+Au collisions at $$ \sqrt{{\textrm{s}}_{\textrm{NN}}} $$ = 200 GeV with the sPHENIX detector
Measurement of charged hadron multiplicity in Au+Au collisions at $$ \sqrt{{\textrm{s}}_{\textrm{NN}}} $$ = 200 GeV with the sPHENIX detector Open
A bstract The pseudorapidity distribution of charged hadrons produced in Au+Au collisions at a center-of-mass energy of $$ \sqrt{{\textrm{s}}_{\textrm{NN}}} $$ = 200 GeV is measured using data collected by the sPHENIX detector. Charge…
View article: Application of a high-resolution melt assay for monitoring SARS-CoV-2 variants in Burkina Faso and Kenya
Application of a high-resolution melt assay for monitoring SARS-CoV-2 variants in Burkina Faso and Kenya Open
The rapid emergence and global dissemination of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) highlighted a need for robust, adaptable surveillance systems. However, financial and infrastructure requirements for whole-genome…
View article: Measurement of the transverse energy density in Au+Au collisions at $\sqrt{s_{NN}} = 200$ GeV with the sPHENIX detector
Measurement of the transverse energy density in Au+Au collisions at $\sqrt{s_{NN}} = 200$ GeV with the sPHENIX detector Open
This paper reports measurements of the transverse energy per unit pseudorapidity ($dE_{T}/dη$) produced in Au+Au collisions at $\sqrt{s_{NN}} = 200$ GeV, performed with the sPHENIX detector at the Relativistic Heavy Ion Collider (RHIC). Th…
View article: Measurement of charged hadron multiplicity in Au+Au collisions at $\sqrt{\text{s}_{\text{NN}}} = 200$ GeV with the sPHENIX detector
Measurement of charged hadron multiplicity in Au+Au collisions at $\sqrt{\text{s}_{\text{NN}}} = 200$ GeV with the sPHENIX detector Open
The pseudorapidity distribution of charged hadrons produced in Au+Au collisions at a center-of-mass energy of $\sqrt{s_\mathrm{NN}} = 200$ GeV is measured using data collected by the sPHENIX detector. Charged hadron yields are extracted by…
View article: Improved genetic screening with zygosity detection through multiplex high‐resolution melting curve analysis and biochemical characterisation for <scp>G6PD</scp> deficiency
Improved genetic screening with zygosity detection through multiplex high‐resolution melting curve analysis and biochemical characterisation for <span>G6PD</span> deficiency Open
Accurate diagnosis of glucose‐6‐phosphate dehydrogenase (G6PD) deficiency is crucial for relapse malaria treatment using 8‐aminoquinolines (primaquine and tafenoquine), which can trigger haemolytic anaemia in G6PD‐deficient individuals. Th…
View article: Head-to-head comparison of anterior nares and nasopharyngeal swabs for SARS-CoV-2 antigen detection in a community drive-through test centre in the UK
Head-to-head comparison of anterior nares and nasopharyngeal swabs for SARS-CoV-2 antigen detection in a community drive-through test centre in the UK Open
Objective To conduct a head-to-head diagnostic accuracy evaluation of anterior nares (AN) and nasopharyngeal (NP) swabs for SARS-CoV-2 antigen detection using two brands of rapid diagnostic tests (Ag-RDT). Methods Two prospective diagnosti…
View article: Detection of mpox and other orthopoxviruses using a lateral flow device as a point-of-care diagnostic
Detection of mpox and other orthopoxviruses using a lateral flow device as a point-of-care diagnostic Open
In 2022, the World Health Organization declared the worldwide outbreak of mpox to be a public health emergency of international concern. The causative monkeypox virus (MPXV) belonged to clade IIb and is transmitted through sexual contact w…
View article: A comparative study of traditional and molecular diagnostic methods for detection of gastrointestinal parasites in Nepalese migrants to the UK
A comparative study of traditional and molecular diagnostic methods for detection of gastrointestinal parasites in Nepalese migrants to the UK Open
Examination of a single faecal sample using qPCR alone showed superior or equivalent sensitivity to traditional methods for most GIP infections when both were compared to the reference standard. Combining molecular and traditional methods …
View article: Optimization of SARS-CoV-2 culture from clinical samples for clinical trial applications
Optimization of SARS-CoV-2 culture from clinical samples for clinical trial applications Open
Clinical trials of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) therapeutics often include virological secondary endpoints to compare viral clearance and viral load reduction between treatment and placebo arms. This is typi…
View article: Utility, feasibility, and socio-demographic considerations in the diagnosis of bacterial RTI's by GC-IMS breath analysis
Utility, feasibility, and socio-demographic considerations in the diagnosis of bacterial RTI's by GC-IMS breath analysis Open
Diagnosis of respiratory tract infections (RTIs), especially in primary care, is typically made on clinical features and in the absence of quick and reliable diagnostic tests. Even in secondary care, where diagnostic microbiology facilitie…
View article: Finding the missed millions: innovations to bring tuberculosis diagnosis closer to key populations
Finding the missed millions: innovations to bring tuberculosis diagnosis closer to key populations Open
View article: The Hidden Hand of Asymptomatic Infection Hinders Control of Neglected Tropical Diseases: A Modeling Analysis
The Hidden Hand of Asymptomatic Infection Hinders Control of Neglected Tropical Diseases: A Modeling Analysis Open
Background Neglected tropical diseases are responsible for considerable morbidity and mortality in low-income populations. International efforts have reduced their global burden, but transmission is persistent and case-finding-based interv…
View article: A panel of recombinant <i>Leishmania donovani</i> cell surface and secreted proteins identifies LdBPK_323600.1 as a serological marker of symptomatic infection
A panel of recombinant <i>Leishmania donovani</i> cell surface and secreted proteins identifies LdBPK_323600.1 as a serological marker of symptomatic infection Open
Visceral leishmaniasis is a deadly infectious disease and is one of the world’s major neglected health problems. Because the symptoms of infection are similar to other endemic diseases, accurate diagnosis is crucial for appropriate treatme…
View article: Application of a High-Resolution Melt Assay for Monitoring SARS-CoV-2 Variants in Burkina Faso and Kenya
Application of a High-Resolution Melt Assay for Monitoring SARS-CoV-2 Variants in Burkina Faso and Kenya Open
The rapid emergence and global dissemination of SARS-CoV-2 highlighted a need for robust, adaptable surveillance systems. However, financial and infrastructure requirements for whole genome sequencing (WGS) mean most surveillance data have…
View article: Optimisation of SARS-CoV-2 culture from clinical samples for clinical trial applications
Optimisation of SARS-CoV-2 culture from clinical samples for clinical trial applications Open
Clinical trials of SARS-CoV-2 therapeutics often include virological secondary endpoints to compare viral clearance and viral load reduction between treatment and placebo arms. This is typically achieved using RT-qPCR, which cannot differe…
View article: Genetic analysis and molecular basis of G6PD deficiency among malaria patients in Thailand: implications for safe use of 8-aminoquinolines
Genetic analysis and molecular basis of G6PD deficiency among malaria patients in Thailand: implications for safe use of 8-aminoquinolines Open
View article: Molecular characterization of G6PD mutations identifies new mutations and a high frequency of intronic variants in Thai females
Molecular characterization of G6PD mutations identifies new mutations and a high frequency of intronic variants in Thai females Open
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an X-linked enzymopathy caused by mutations in the G6PD gene. A medical concern associated with G6PD deficiency is acute hemolytic anemia induced by certain foods, drugs, and infection…
View article: The hidden hand of asymptomatic infection hinders control of neglected tropical diseases
The hidden hand of asymptomatic infection hinders control of neglected tropical diseases Open
Neglected tropical diseases are responsible for considerable morbidity and mortality in low-income populations. International efforts have reduced their global burden, but transmission is persistent and case-finding-based interventions rar…
View article: Comparison of the analytical and clinical sensitivity of thirty-four rapid antigen tests with prevalent SARS-CoV-2 variants of concern during the COVID-19 pandemic in the UK
Comparison of the analytical and clinical sensitivity of thirty-four rapid antigen tests with prevalent SARS-CoV-2 variants of concern during the COVID-19 pandemic in the UK Open
Antigen-detection rapid diagnostic tests (Ag-RDTs) have become a central pillar for the management of COVID-19 worldwide due to their speed and ease of use, and are now being developed for use in other emerging outbreaks. Like other viruse…
View article: Multicenter Diagnostic Evaluation of OnSite COVID-19 Rapid Test (CTK Biotech) among Symptomatic Individuals in Brazil and the United Kingdom
Multicenter Diagnostic Evaluation of OnSite COVID-19 Rapid Test (CTK Biotech) among Symptomatic Individuals in Brazil and the United Kingdom Open
Evaluating rapid diagnostic tests in diverse populations is essential to improving diagnostic responses as it gives an indication of the accuracy in real-world scenarios. In the case of rapid diagnostic testing within this pandemic, latera…
View article: PREVALENCE OF ASYMPTOMATIC LEISHMANIA INFECTION IN PEOPLE LIVING WITH HIV AND PROGRESSION TO SYMPTOMATIC VISCERAL LEISHMANIASIS IN BIHAR, INDIA
PREVALENCE OF ASYMPTOMATIC LEISHMANIA INFECTION IN PEOPLE LIVING WITH HIV AND PROGRESSION TO SYMPTOMATIC VISCERAL LEISHMANIASIS IN BIHAR, INDIA Open
Intro: People living with HIV (PLHIV) have an increased risk of developing visceral leishmaniasis (VL) and poor outcomes compared to HIV-negative individuals. Here, we aim to establish the prevalence and determinants of asymptomatic Leishm…
View article: Supplementary Figure from Artificial Intelligence-Assisted Serial Analysis of Clinical Cancer Genomics Data Identifies Changing Treatment Recommendations and Therapeutic Targets
Supplementary Figure from Artificial Intelligence-Assisted Serial Analysis of Clinical Cancer Genomics Data Identifies Changing Treatment Recommendations and Therapeutic Targets Open
Supplementary Figure from Artificial Intelligence-Assisted Serial Analysis of Clinical Cancer Genomics Data Identifies Changing Treatment Recommendations and Therapeutic Targets
View article: Supplementary Figure from Artificial Intelligence-Assisted Serial Analysis of Clinical Cancer Genomics Data Identifies Changing Treatment Recommendations and Therapeutic Targets
Supplementary Figure from Artificial Intelligence-Assisted Serial Analysis of Clinical Cancer Genomics Data Identifies Changing Treatment Recommendations and Therapeutic Targets Open
Supplementary Figure from Artificial Intelligence-Assisted Serial Analysis of Clinical Cancer Genomics Data Identifies Changing Treatment Recommendations and Therapeutic Targets
View article: Supplementary Figure from Artificial Intelligence-Assisted Serial Analysis of Clinical Cancer Genomics Data Identifies Changing Treatment Recommendations and Therapeutic Targets
Supplementary Figure from Artificial Intelligence-Assisted Serial Analysis of Clinical Cancer Genomics Data Identifies Changing Treatment Recommendations and Therapeutic Targets Open
Supplementary Figure from Artificial Intelligence-Assisted Serial Analysis of Clinical Cancer Genomics Data Identifies Changing Treatment Recommendations and Therapeutic Targets
View article: Supplementary Figure from Artificial Intelligence-Assisted Serial Analysis of Clinical Cancer Genomics Data Identifies Changing Treatment Recommendations and Therapeutic Targets
Supplementary Figure from Artificial Intelligence-Assisted Serial Analysis of Clinical Cancer Genomics Data Identifies Changing Treatment Recommendations and Therapeutic Targets Open
Supplementary Figure from Artificial Intelligence-Assisted Serial Analysis of Clinical Cancer Genomics Data Identifies Changing Treatment Recommendations and Therapeutic Targets
View article: Supplementary Figure from Artificial Intelligence-Assisted Serial Analysis of Clinical Cancer Genomics Data Identifies Changing Treatment Recommendations and Therapeutic Targets
Supplementary Figure from Artificial Intelligence-Assisted Serial Analysis of Clinical Cancer Genomics Data Identifies Changing Treatment Recommendations and Therapeutic Targets Open
Supplementary Figure from Artificial Intelligence-Assisted Serial Analysis of Clinical Cancer Genomics Data Identifies Changing Treatment Recommendations and Therapeutic Targets
View article: Supplementary Figure from Artificial Intelligence-Assisted Serial Analysis of Clinical Cancer Genomics Data Identifies Changing Treatment Recommendations and Therapeutic Targets
Supplementary Figure from Artificial Intelligence-Assisted Serial Analysis of Clinical Cancer Genomics Data Identifies Changing Treatment Recommendations and Therapeutic Targets Open
Supplementary Figure from Artificial Intelligence-Assisted Serial Analysis of Clinical Cancer Genomics Data Identifies Changing Treatment Recommendations and Therapeutic Targets
View article: Data from Artificial Intelligence-Assisted Serial Analysis of Clinical Cancer Genomics Data Identifies Changing Treatment Recommendations and Therapeutic Targets
Data from Artificial Intelligence-Assisted Serial Analysis of Clinical Cancer Genomics Data Identifies Changing Treatment Recommendations and Therapeutic Targets Open
Purpose:Given the pace of predictive biomarker and targeted therapy development, it is unknown whether repeat annotation of the same next-generation sequencing data can identify additional clinically actionable targets that could be therap…
View article: Supplementary Figure from Artificial Intelligence-Assisted Serial Analysis of Clinical Cancer Genomics Data Identifies Changing Treatment Recommendations and Therapeutic Targets
Supplementary Figure from Artificial Intelligence-Assisted Serial Analysis of Clinical Cancer Genomics Data Identifies Changing Treatment Recommendations and Therapeutic Targets Open
Supplementary Figure from Artificial Intelligence-Assisted Serial Analysis of Clinical Cancer Genomics Data Identifies Changing Treatment Recommendations and Therapeutic Targets