Emily J. Van Etten
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View article: Network segregation is associated with processing speed in the cognitively healthy oldest-old
Network segregation is associated with processing speed in the cognitively healthy oldest-old Open
The brain is organized into systems and networks of interacting components. The functional connections among these components give insight into the brain’s organization and may underlie some cognitive effects of aging. Examining the relati…
View article: “Surviving and Thriving”: evidence for cortical GABA stabilization in cognitively-intact oldest-old adults
“Surviving and Thriving”: evidence for cortical GABA stabilization in cognitively-intact oldest-old adults Open
View article: Peritraumatic Context and Long-Term Outcomes of Concussion
Peritraumatic Context and Long-Term Outcomes of Concussion Open
Importance There has been a great deal of interest in mild traumatic brain injury (mTBI) and posttraumatic stress disorder (PTSD) and their association with one another, yet their interaction and subsequent associations with long-term outc…
View article: Impact of age and apolipoprotein E ε4 status on regional white matter hyperintensity volume and cognition in healthy aging
Impact of age and apolipoprotein E ε4 status on regional white matter hyperintensity volume and cognition in healthy aging Open
Objective: White matter hyperintensity (WMH) volume is a neuroimaging marker of lesion load related to small vessel disease that has been associated with cognitive aging and Alzheimer’s disease (AD) risk. Method: The present study sought t…
View article: Learning ratio performance on a brief visual learning and memory test moderates cognitive training gains in Double Decision task in healthy older adults
Learning ratio performance on a brief visual learning and memory test moderates cognitive training gains in Double Decision task in healthy older adults Open
View article: Regional covariance of white matter hyperintensity volume patterns associated with hippocampal volume in healthy aging
Regional covariance of white matter hyperintensity volume patterns associated with hippocampal volume in healthy aging Open
Hippocampal volume is particularly sensitive to the accumulation of total brain white matter hyperintensity volume (WMH) in aging, but how the regional distribution of WMH volume differentially impacts the hippocampus has been less studied…
View article: The impact of a tDCS and cognitive training intervention on task-based functional connectivity
The impact of a tDCS and cognitive training intervention on task-based functional connectivity Open
View article: 1 Task-Based Functional Connectivity and Network Segregation of the Useful Field of View (UFOV) fMRI task
1 Task-Based Functional Connectivity and Network Segregation of the Useful Field of View (UFOV) fMRI task Open
Objective: Interventions using a cognitive training paradigm called the Useful Field of View (UFOV) task have shown to be efficacious in slowing cognitive decline. However, no studies have looked at the engagement of functional networks du…
View article: 9 Connecting memory and functional brain networks in older adults: a resting state fMRI study
9 Connecting memory and functional brain networks in older adults: a resting state fMRI study Open
Objective: Nonpathological aging has been linked to decline in both verbal and visuospatial memory abilities in older adults. Disruptions in resting-state functional connectivity within well-characterized, higherorder cognitive brain netwo…
View article: 78 BVMT-R Learning Ratio Moderates Cognitive Training Gains in Useful Field of View Task in Healthy Older Adults
78 BVMT-R Learning Ratio Moderates Cognitive Training Gains in Useful Field of View Task in Healthy Older Adults Open
Objective: Cognitive training using a visual speed-of-processing task, called the Useful Field of View (UFOV) task, reduced dementia risk and reduced decline in activities of daily living at a 10-year follow-up in older adults. However, th…
View article: 53 2-Back Performance Does Not Differ Between Cognitive Training Groups in Older Adults Without Dementia
53 2-Back Performance Does Not Differ Between Cognitive Training Groups in Older Adults Without Dementia Open
Objective: Cognitive training is a non-pharmacological intervention aimed at improving cognitive function across a single or multiple domains. Although the underlying mechanisms of cognitive training and transfer effects are not well-chara…
View article: 2 Higher White Matter Hyperintensity Load Adversely Affects Pre-Post Proximal Cognitive Training Performance in Healthy Older Adults
2 Higher White Matter Hyperintensity Load Adversely Affects Pre-Post Proximal Cognitive Training Performance in Healthy Older Adults Open
Objective: Cognitive training has shown promise for improving cognition in older adults. Aging involves a variety of neuroanatomical changes that may affect response to cognitive training. White matter hyperintensities (WMH) are one common…
View article: 6 Adjunctive Transcranial Direct Current Stimulation and Cognitive Training Alters Default Mode and Frontoparietal Control Network Connectivity in Older Adults
6 Adjunctive Transcranial Direct Current Stimulation and Cognitive Training Alters Default Mode and Frontoparietal Control Network Connectivity in Older Adults Open
Objective: Aging is associated with disruptions in functional connectivity within the default mode (DMN), frontoparietal control (FPCN), and cingulo-opercular (CON) resting-state networks. Greater within-network connectivity predicts bette…
View article: 61 Network Segregation Predicts Processing Speed in the Cognitively Healthy Oldest-old
61 Network Segregation Predicts Processing Speed in the Cognitively Healthy Oldest-old Open
Objective: Understanding the factors contributing to optimal cognitive function throughout the aging process is essential to better understand successful cognitive aging. Processing speed is an age sensitive cognitive domain that usually d…
View article: Connecting memory and functional brain networks in older adults: a resting-state fMRI study
Connecting memory and functional brain networks in older adults: a resting-state fMRI study Open
View article: The longitudinal impact of the COVID-19 pandemic on health behaviors, psychosocial factors, and cognitive functioning in older adults
The longitudinal impact of the COVID-19 pandemic on health behaviors, psychosocial factors, and cognitive functioning in older adults Open
Background: Older adults are at a greater risk for contracting and experiencing severe illness from COVID-19 and may be further affected by pandemic-related precautions (e.g., social distancing and isolation in quarantine). However, the lo…
View article: Author response: Network segregation is associated with processing speed in the cognitively healthy oldest-old
Author response: Network segregation is associated with processing speed in the cognitively healthy oldest-old Open
View article: Validity of the NIH toolbox cognitive battery in a healthy oldest-old 85+ sample
Validity of the NIH toolbox cognitive battery in a healthy oldest-old 85+ sample Open
Objective: To evaluate the construct validity of the NIH Toolbox Cognitive Battery (NIH TB-CB) in the healthy oldest-old (85+ years old). Method: Our sample from the McKnight Brain Aging Registry consists of 179 individuals, 85 to 99 years…
View article: Task-based functional connectivity of the Useful Field of View (UFOV) fMRI task
Task-based functional connectivity of the Useful Field of View (UFOV) fMRI task Open
View article: Larger and more dentated hippocampal structure is associated with better memory in the oldest-old
Larger and more dentated hippocampal structure is associated with better memory in the oldest-old Open
Episodic memory is widely recognized as a critically important aspect of cognition that is often impacted by cognitive and brain aging. Prior work has shown that episodic memory is related to the presence of teeth-like folds on the dentate…
View article: Higher white matter hyperintensity load adversely affects pre-post proximal cognitive training performance in healthy older adults
Higher white matter hyperintensity load adversely affects pre-post proximal cognitive training performance in healthy older adults Open
View article: Proximal improvement and higher-order resting state network change after multidomain cognitive training intervention in healthy older adults
Proximal improvement and higher-order resting state network change after multidomain cognitive training intervention in healthy older adults Open
View article: The association between head motion during functional magnetic resonance imaging and executive functioning in older adults
The association between head motion during functional magnetic resonance imaging and executive functioning in older adults Open
View article: Cingulo-opercular and frontoparietal control network connectivity and executive functioning in older adults
Cingulo-opercular and frontoparietal control network connectivity and executive functioning in older adults Open
View article: Only within resting state network connectivity of the frontoparietal control and Cingulo Opercular networks predict useful field of view performance
Only within resting state network connectivity of the frontoparietal control and Cingulo Opercular networks predict useful field of view performance Open
Background The Useful Field of View (UFOV) test assesses divided attention/speed of processing and relates to independent activities of daily living. Cognitive training utilizing UFOV improves speed‐of‐processing and reduces dementia risk …
View article: The impact of accuracy on functional neural correlates of the useful field of view (UFOV) task
The impact of accuracy on functional neural correlates of the useful field of view (UFOV) task Open
Background Rapid declines in processing speed performance occur in aging and serve as a critical marker of cognitive abilities. Studies suggest that Useful Field of View (UFOV) training may ameliorate cognitive decline. The ACTIVE trial, c…
View article: Functional Neural Correlates of a Useful Field of View (UFOV)-Based fMRI Task in Older Adults
Functional Neural Correlates of a Useful Field of View (UFOV)-Based fMRI Task in Older Adults Open
Declines in processing speed performance occur in aging and are a critical marker of functional independence in older adults. Studies suggest that Useful Field of View (UFOV) training may ameliorate cognitive decline. Despite its efficacy,…
View article: A-10 Role of Fluid Cognitive Status in the Association of Frontoparietal Control and Cingulo-Opercular Networks with the Useful Field of View Task: Implications for Cognitive Training in Aging
A-10 Role of Fluid Cognitive Status in the Association of Frontoparietal Control and Cingulo-Opercular Networks with the Useful Field of View Task: Implications for Cognitive Training in Aging Open
Objective Training in a divided attention/speed-of-processing task called Useful Field of View (UFOV) reduced dementia risk in older adults. Higher connectivity in resting-state networks involved in attention/inter-network modulation (cing…
View article: Frontal White Matter Hyperintensities and Executive Functioning Performance in Older Adults
Frontal White Matter Hyperintensities and Executive Functioning Performance in Older Adults Open
Frontal lobe structures decline faster than most other brain regions in older adults. Age-related change in the frontal lobe is associated with poorer executive function (e.g., working memory, switching/set-shifting, and inhibitory control…
View article: Influence of regional white matter hyperintensity volume and apolipoprotein E ε4 status on hippocampal volume in healthy older adults
Influence of regional white matter hyperintensity volume and apolipoprotein E ε4 status on hippocampal volume in healthy older adults Open
While total white matter hyperintensity (WMH) volume on magnetic resonance imaging (MRI) has been associated with hippocampal atrophy, less is known about how the regional distribution of WMH volume may differentially affect the hippocampu…