Emma Fidler
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View article: Comprehensive analysis of the role of <i>ASC1</i> and <i>APE2</i> introns on cellular fitness, transcription, and post‐transcriptional dynamics
Comprehensive analysis of the role of <i>ASC1</i> and <i>APE2</i> introns on cellular fitness, transcription, and post‐transcriptional dynamics Open
A splicing‐competent intron has been found to affect the expression of a gene at almost every step between transcription and translation. In this investigation, we performed a comprehensive analysis of the role of an intron from two yeast …
View article: Ssu72: a versatile protein with functions in transcription and beyond
Ssu72: a versatile protein with functions in transcription and beyond Open
Eukaryotic transcription is a complex process involving a vast network of protein and RNA factors that influence gene expression. The main player in transcription is the RNA polymerase that synthesizes the RNA from the DNA template. RNA po…
View article: Sub2: A TFIIB Interacting Protein with Pleiotropic Roles in mRNA Synthesis, Processing and Transport
Sub2: A TFIIB Interacting Protein with Pleiotropic Roles in mRNA Synthesis, Processing and Transport Open
The generally accepted view is that different steps of transcription, mRNA processing and mRNA trafficking are performed by dedicated accessory factors. The research during last couple of decades, however, has challenged this dogma. We rec…