Emma Karlsen
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View article: Trial protocol for Siroskin: a randomised double-blind placebo-controlled trial of topical sirolimus in chemoprevention of facial squamous cell carcinomas in solid organ transplant recipients
Trial protocol for Siroskin: a randomised double-blind placebo-controlled trial of topical sirolimus in chemoprevention of facial squamous cell carcinomas in solid organ transplant recipients Open
Background: Keratinocyte carcinomas such as Basal Cell Carcinomas and Squamous Cell Carcinomas are a major burden affecting morbidity and mortality in solid organ transplant recipients (SOTRs). Best treatment includes frequent skin checks …
View article: Association between elevated peripheral blood eosinophil count and respiratory outcomes in adults with cystic fibrosis
Association between elevated peripheral blood eosinophil count and respiratory outcomes in adults with cystic fibrosis Open
The high eosinophil group experienced increased respiratory symptoms, but the rates of lung function decline and PEx were comparable between groups.
View article: Epidermal Growth Factor Receptor Expression and Resistance Patterns to Targeted Therapy in Non-Small Cell Lung Cancer: A Review
Epidermal Growth Factor Receptor Expression and Resistance Patterns to Targeted Therapy in Non-Small Cell Lung Cancer: A Review Open
Globally, lung cancer is the leading cause of cancer-related death. The majority of non-small cell lung cancer (NSCLC) tumours express epidermal growth factor receptor (EGFR), which allows for precise and targeted therapy in these patients…
View article: Cystic fibrosis–related diabetes onset can be predicted using biomarkers measured at birth
Cystic fibrosis–related diabetes onset can be predicted using biomarkers measured at birth Open
We demonstrated clinical utility by comparing CFRD prevalence rates between the top 10% of individuals with the highest risk and the bottom 10% with the lowest risk. A web-based application was developed to provide practitioners with patie…
View article: Flecainide overdose-induced Brugada electrocardiogram pattern
Flecainide overdose-induced Brugada electrocardiogram pattern Open
A 64-year-old female with paroxysmal atrial fibrillation presented to the emergency department with atrial fibrillation and rapid ventricular rate (Figure 1A), which was refractory to her usual combination doses of ‘pill-in-pocket’ metopro…