Emma R. Hinkle
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View article: Author Correction: Stretching muscle cells induces transcriptional and splicing transitions and changes in SR proteins
Author Correction: Stretching muscle cells induces transcriptional and splicing transitions and changes in SR proteins Open
View article: Stretching muscle cells induces transcriptional and splicing transitions and changes in SR proteins
Stretching muscle cells induces transcriptional and splicing transitions and changes in SR proteins Open
View article: Alternative splicing of the Snap23 microexon is regulated by MBNL, QKI, and RBFOX2 in a tissue-specific manner and is altered in striated muscle diseases
Alternative splicing of the Snap23 microexon is regulated by MBNL, QKI, and RBFOX2 in a tissue-specific manner and is altered in striated muscle diseases Open
The reprogramming of alternative splicing networks during development is a hallmark of tissue maturation and identity. Alternative splicing of microexons (small, genomic regions ≤ 51 nucleotides) functionally regulate protein-protein inter…
View article: Alternative splicing regulation of membrane trafficking genes during myogenesis
Alternative splicing regulation of membrane trafficking genes during myogenesis Open
Alternative splicing transitions occur during organ development, and, in numerous diseases, splicing programs revert to fetal isoform expression. We previously found that extensive splicing changes occur during postnatal mouse heart develo…
View article: ViaFuse: Fiji macros to calculate skeletal muscle cell viability and fusion index
ViaFuse: Fiji macros to calculate skeletal muscle cell viability and fusion index Open
View article: The synaptosome-associated protein 23 (SNAP23) is necessary for proper myogenesis
The synaptosome-associated protein 23 (SNAP23) is necessary for proper myogenesis Open
Vesicle-mediated transport is necessary for maintaining cellular homeostasis and proper signaling. The synaptosome-associated protein 23 (SNAP23) is a member of the SNARE protein family and mediates the vesicle docking and membrane fusion …
View article: Author Correction: Stretching muscle cells induces transcriptional and splicing transitions and changes in SR proteins
Author Correction: Stretching muscle cells induces transcriptional and splicing transitions and changes in SR proteins Open
View article: Stretching muscle cells induces transcriptional and splicing transitions and changes in SR proteins
Stretching muscle cells induces transcriptional and splicing transitions and changes in SR proteins Open
Alternative splicing is an RNA processing mechanism involved in skeletal muscle development and pathology. Muscular diseases exhibit splicing alterations and changes in mechanobiology leading us to investigate the interconnection between m…
View article: The synaptosome‐associated protein 23 ( <scp>SNAP23</scp> ) is necessary for proper myogenesis
The synaptosome‐associated protein 23 ( <span>SNAP23</span> ) is necessary for proper myogenesis Open
Vesicle‐mediated transport is necessary for maintaining cellular homeostasis and proper signaling. The synaptosome‐associated protein 23 (SNAP23) is a member of the SNARE protein family and mediates the vesicle docking and membrane fusion …
View article: Alternative splicing regulation of membrane trafficking genes during myogenesis
Alternative splicing regulation of membrane trafficking genes during myogenesis Open
Alternative splicing transitions occur during organ development, and, in numerous diseases, splicing programs revert to fetal isoform expression. We previously found that extensive splicing changes occur during postnatal mouse heart develo…
View article: ViaFuse: Fiji macros to calculate skeletal muscle cell viability and fusion index
ViaFuse: Fiji macros to calculate skeletal muscle cell viability and fusion index Open
View article: Additional file 1 of ViaFuse: Fiji macros to calculate skeletal muscle cell viability and fusion index
Additional file 1 of ViaFuse: Fiji macros to calculate skeletal muscle cell viability and fusion index Open
Additional file 1: Supplementary Table 1.
View article: A piggyBac-based toolkit for inducible genome editing in mammalian cells
A piggyBac-based toolkit for inducible genome editing in mammalian cells Open
We describe the development and application of a novel series of vectors that facilitate CRISPR-Cas9-mediated genome editing in mammalian cells, which we call CRISPR-Bac. CRISPR-Bac leverages the piggyBac transposon to randomly insert CRIS…
View article: RNA processing in skeletal muscle biology and disease
RNA processing in skeletal muscle biology and disease Open
RNA processing encompasses the capping, cleavage, polyadenylation and alternative splicing of pre-mRNA. Proper muscle development relies on precise RNA processing, driven by the coordination between RNA-binding proteins. Recently, skeletal…
View article: A piggyBac-based toolkit for inducible genome editing in mammalian cells
A piggyBac-based toolkit for inducible genome editing in mammalian cells Open
We describe the development and application of a novel series of vectors that facilitate CRISPR-Cas9-mediated genome editing in mammalian cells, which we call CRISPR-Bac. CRISPR-Bac leverages the piggyBac transposon to randomly insert CRIS…