Emmanuel Chrysos
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View article: Multicentre prospective study on the diagnostic and prognostic validity of malnutrition assessment tools in surgery
Multicentre prospective study on the diagnostic and prognostic validity of malnutrition assessment tools in surgery Open
Background Malnutrition is a risk factor for postoperative morbidity but the optimal tool for the assessment of malnutrition is unclear. Methods This is a prospective multicentre cohort study. Consecutive patients undergoing elective or em…
View article: Current and Future Trends of Colorectal Cancer Treatment: Exploring Advances in Immunotherapy
Current and Future Trends of Colorectal Cancer Treatment: Exploring Advances in Immunotherapy Open
Cancer of the colon and rectum (CRC) has been identified among the three most prevalent types of cancer and cancer-related deaths for both sexes. Even though significant progress in surgical and chemotherapeutic techniques has markedly imp…
View article: Development and internal validation of a clinical prediction model for serious complications after emergency laparotomy
Development and internal validation of a clinical prediction model for serious complications after emergency laparotomy Open
Purpose Emergency laparotomy (EL) is a common operation with high risk for postoperative complications, thereby requiring accurate risk stratification to manage vulnerable patients optimally. We developed and internally validated a predict…
View article: External Validation of the American College of Surgeons Surgical Risk Calculator in Elderly Patients Undergoing General Surgery Operations
External Validation of the American College of Surgeons Surgical Risk Calculator in Elderly Patients Undergoing General Surgery Operations Open
Preoperative risk stratification in the elderly surgical patient is an essential part of contemporary perioperative care and can be done with the use of the American College of Surgeons Surgical Risk Calculator (ACS-SRC). However, data on …
View article: The Hellenic Emergency Laparotomy Study (HELAS): A Prospective Multicentre Study on the Outcomes of Emergency Laparotomy in Greece
The Hellenic Emergency Laparotomy Study (HELAS): A Prospective Multicentre Study on the Outcomes of Emergency Laparotomy in Greece Open
Background Emergency laparotomy (EL) is accompanied by high post‐operative morbidity and mortality which varies significantly between countries and populations. The aim of this study is to report outcomes of emergency laparotomy in Greece …
View article: A Comparison of the Malnutrition Universal Screening Tool (MUST) and the Mini Nutritional Assessment-Short Form (MNA-SF) Tool for Older Patients Undergoing General Surgery
A Comparison of the Malnutrition Universal Screening Tool (MUST) and the Mini Nutritional Assessment-Short Form (MNA-SF) Tool for Older Patients Undergoing General Surgery Open
The optimal malnutrition screening tool in geriatric surgery has yet to be determined. Herein, we compare two main tools in older patients undergoing general surgery operations. Older patients (>65 years old) who underwent general surgery …
View article: Factors Associated with Malnutrition and Its Impact on Postoperative Outcomes in Older Patients
Factors Associated with Malnutrition and Its Impact on Postoperative Outcomes in Older Patients Open
Malnutrition is associated with dismal treatment outcomes in older patients but its impact in geriatric surgery has not been studied extensively. Herein, we report the prevalence of malnutrition risk, its risk factors and its association w…
View article: Intestinal Microbiota in Colorectal Cancer Surgery
Intestinal Microbiota in Colorectal Cancer Surgery Open
The intestinal microbiota consists of numerous microbial species that collectively interact with the host, playing a crucial role in health and disease. Colorectal cancer is well-known to be related to dysbiotic alterations in intestinal m…
View article: Current and Future Trends in Molecular Biomarkers for Diagnostic, Prognostic, and Predictive Purposes in Non-Melanoma Skin Cancer
Current and Future Trends in Molecular Biomarkers for Diagnostic, Prognostic, and Predictive Purposes in Non-Melanoma Skin Cancer Open
Skin cancer represents the most common type of cancer among Caucasians and presents in two main forms: melanoma and non-melanoma skin cancer (NMSC). NMSC is an umbrella term, under which basal cell carcinoma (BCC), squamous cell carcinoma …
View article: Multiple magnet ingestion causing instestinal obstruction and entero-enteric fistula: Which imaging modality besides radiographs? A case report
Multiple magnet ingestion causing instestinal obstruction and entero-enteric fistula: Which imaging modality besides radiographs? A case report Open
Awareness of the potentially devastating effects of multiple magnets passing the pylorus and the contribution of different imaging modalities for the diagnosis are emphasized and discussed.
View article: Case Report: A Rare Case of Appendicitis Incarcerated in an Inguinal Hernia in an 8 Year Old Male Child
Case Report: A Rare Case of Appendicitis Incarcerated in an Inguinal Hernia in an 8 Year Old Male Child Open
Introduction: Amyand’s hernia may present with the inflammation of the appendix vermiform is enclosed in its sac. Its diagnosis is very difficult in the pre-operative period, it is usually an incidental finding. Case presentation: We prese…
View article: CRHR2/Ucn2 signaling is a novel regulator of miR‐7/YY1/Fas circuitry contributing to reversal of colorectal cancer cell resistance to Fas‐mediated apoptosis
CRHR2/Ucn2 signaling is a novel regulator of miR‐7/YY1/Fas circuitry contributing to reversal of colorectal cancer cell resistance to Fas‐mediated apoptosis Open
Colorectal cancer (CRC) responds poorly to immuno‐mediated cytotoxicity. Underexpression of corticotropin‐releasing‐hormone‐receptor‐2 (CRHR2) in CRC, promotes tumor survival, growth and Epithelial to Mesenchymal Transition (EMT), in vitro…
View article: Well-promising outcomes with vacuum-assisted closure in an infected wound following laparotomy: A case report
Well-promising outcomes with vacuum-assisted closure in an infected wound following laparotomy: A case report Open
The simultaneous use of instillation and constant pressure seemed to be superior in comparison with NPWT alone. Compared to conventional methods, the use of VAC ends to better outcomes, in cases of infected wounds following laparotomy.
View article: Pancreatic Resection for Metastasis to the Pancreas from Colon and Lung Cancer, and Osteosarcoma
Pancreatic Resection for Metastasis to the Pancreas from Colon and Lung Cancer, and Osteosarcoma Open
Context Pancreatic resection for a metastatic colon, lung cancer or an osteosarcoma has rarely been reported in the literature and there is controversy regarding recurrence and the overall survival of these patients. We herein evaluate the…
View article: Advanced Mesodermal (Müllerian) Adenosarcoma of the Ovary: Metastases to the Lungs, Mouth, and Brain
Advanced Mesodermal (Müllerian) Adenosarcoma of the Ovary: Metastases to the Lungs, Mouth, and Brain Open
Background . A malignant mixed Müllerian tumor (MMMT) is a malignant neoplasm found in the uterus, the ovaries, the fallopian tubes, and other parts of the body that contains both carcinomatous (epithelial tissue) and sarcomatous (connecti…