Emmanuel Eru
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Impact of Black Seed Oil on Male Sex Hormones and Binding Proteins in Alloxan-Induced Diabetic Wistar Rats Open
Background: Diabetes is a metabolic disease that has a detrimental effect on human health and patients' quality of life. The number of male patients with diabetes is increasing, and so are the infertility problems in the male population. T…
Interaction between aqueous extract of Moringa oleifera leaves and rabeprazole in treatment of ethanol induced gastric ulcer in Wistar rats Open
Background: The effect of concomitant use of herbs and conventional drugs is not widely known because it hasn’t been a common practice especially among the elite and those resident at the urban centers but very common among the rural duele…
Role of Haematological Indices, Interleukin-10, Tumour Necrosis Factor and Vascular Endothelial Growth Factor on Gastric Ulcer Healing in Obese Wistar Rats: Effect of Garlic Oil Open
Haematological indices, cytokines and growth factors are among the factors that impact inflammatory processes. The impact of obesity on gastric ulcer (GU) healing is not fully known. Natural products like garlic oil (GO) which may be readi…
Relationship between Body Mass Index, Waist-to-hip Ratio and Glycaemic control status of Adult Diabetics in Makurdi, Nigeria Open
Background: Diabetes mellitus is a metabolic disorder that affects carbohydrate, protein and fat metabolism. Body mass index (BMI) and waist-to-hip ratio (WHR) are known anthropometric measurements used to access body fat. Good glycaemic c…
Inhibitory Effect of Moringa Oleifera on Gastric Acid Secretion Open
The effect of orally ingested substance on gastric acid secretion, have been subject to human investigation. This study was carried out to investigate the inhibitory effect of Moringa oleifera on gastric acid secretion. Fifteen (15) adult …
Amerliorative Effect of Vernonia Amygdalina in Dexamethasone Induced Hyperglycaemia Open
Hyperglycaemia has been found to be one of the main side effects associated with dexamethasone administration. Vernonia amygdalina(VA)-bitter leave is a common shrub consumed in Nigeria. This study was carried out to investigate the amelio…
Aqueous Extract of Capsicum Frutescens Exhibits Saturation Phenomenon in Gastric Acid Secretion Open
The effects of orally ingested substances on gastric function have been the subject of human investigation almost since the discovery of hydrochloric acid in gastric juice by Prout in 1824. Capsicum frutescens is a ubiquitous spice widely …
Capsicum Frutescens Exhibits Tachyphylaxis In Gastric Acid Secretion Open
Capsicum frutescens has been found to increase gastric acid secretion (Ibu et al., 1993). Capsicum frutescens is a species of pepper that is widely used as spice both in Nigeria and elsewhere (Ibu et al., 1993). There is paucity of literat…
Comparative Effect of Vernonia Amygdalina and Metformin in Alloxan Induced Diabetes Mellitus Open
Metformin is a biguanide and its mechanism of action is exhibited at extra pancreatic level. In clinical practice, it is the first line therapy recommended for newly diagnosed type 2 diabetes mellitus patient (ADA, 2014). Vernonia amygdali…
Synergestic Effect of Vernonia Amygdalina and Glimepiride on Alloxan Induced Hyperglycaemia Open
Glimepiride is a sulfonylurea whose mechanism of action is to stimulate insulin release from the beta cell of the pancreas. It is an oral hypoglycaemic agent that is widely used in the management of type 2 Diabetes mellitus in Nigeria. Als…