Emmanuel Messas
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View article: Short- and Long-Term Effects of Pulsed Ultrasound Cavitation Therapy of Calcified Valvular Interstitial Cells in Culture
Short- and Long-Term Effects of Pulsed Ultrasound Cavitation Therapy of Calcified Valvular Interstitial Cells in Culture Open
These studies suggest that ultrasound therapy, currently limited to very severe aortic stenosis, could be of interest at an earlier stage of the disease.
View article: Evaluation of Ultrasound Microflow Imaging as an Assessment Tool for Digital Arteries in Thromboangiitis Obliterans
Evaluation of Ultrasound Microflow Imaging as an Assessment Tool for Digital Arteries in Thromboangiitis Obliterans Open
Ultrasound imaging using MFI mode for digital artery analysis is a promising contender to DSA for diagnosing TAO. Careful analysis allows for the detection of occlusion-recovery, flow analysis, and the detection of parietal arterial anomal…
View article: Advancements in Noncontrast Ultrasound Imaging for Low-Velocity Flow: A Technical Review and Clinical Applications in Vascular Medicine
Advancements in Noncontrast Ultrasound Imaging for Low-Velocity Flow: A Technical Review and Clinical Applications in Vascular Medicine Open
Visualizing the arterial tree using ultrasound, from the aorta to the small vessels, has significantly improved over time due to advances in ultrasound imaging technology. Initially limited to exploring the major vessels, ultrasound analys…
View article: Is Multimodal Better? A Systematic Review of Multimodal<i>versus</i>Unimodal Machine Learning in Clinical Decision-Making
Is Multimodal Better? A Systematic Review of Multimodal<i>versus</i>Unimodal Machine Learning in Clinical Decision-Making Open
Machine learning has demonstrated success in clinical decision-making, yet the added value of multimodal approaches over unimodal models remains unclear. This systematic review evaluates studies comparing multimodal and unimodal ML algorit…
View article: Prix Nobel de physique 2024 : John J. Hopfield et Geoffrey E. Hinton
Prix Nobel de physique 2024 : John J. Hopfield et Geoffrey E. Hinton Open
Le 8 octobre 2024, le prix Nobel de physique a été attribué à John J. Hopfield, professeur à l’université de Princeton (États-Unis), et à Geoffrey E. Hinton, professeur à l’université de Toronto (Canada), pour leurs « découvertes fondament…
View article: Assessment of microvascular flow in human atherosclerotic carotid plaques using ultrasound localization microscopy
Assessment of microvascular flow in human atherosclerotic carotid plaques using ultrasound localization microscopy Open
The study was sponsored and funded by Assistance Publique-Hôpitaux de Paris (CRC 1806 APHP INNOVATION 2018). Co-funding by ART (Technological Research Accelerator) biomedical ultrasound program of INSERM, France.
View article: Clinical outcomes in patients in any phase of <scp>CML</scp> treated with ponatinib in France—Data from the <scp>TOPASE</scp> observational study
Clinical outcomes in patients in any phase of <span>CML</span> treated with ponatinib in France—Data from the <span>TOPASE</span> observational study Open
Summary The TOPASE study was set up to evaluate the outcomes of chronic myeloid leukaemia [CML] patients treated with ponatinib (PON) in a real‐world setting in France. One hundred and twenty CML patients, 105 in chronic phase (CP), 8 in a…
View article: Non-Invasive Ultrasound Therapy for Severe Aortic Stenosis: Early Effects on the Valve, Ventricle, and Cardiac Biomarkers (A Case Series)
Non-Invasive Ultrasound Therapy for Severe Aortic Stenosis: Early Effects on the Valve, Ventricle, and Cardiac Biomarkers (A Case Series) Open
Background: Transcatheter aortic valve replacement (TAVR) was developed for inoperable patients with severe aortic stenosis. However, despite TAVR advancements, some patients remain untreated due to complex comorbidities, necessitating les…
View article: Acute phase determinant of post-thrombotic syndrome: A review of the literature
Acute phase determinant of post-thrombotic syndrome: A review of the literature Open
View article: Flow Quantification Within the Aortic Ejection Tract Using 4d Flow in Patients with a Bicuspid Aortic Valve: Impacts on Aortic Regurgitation Assessment
Flow Quantification Within the Aortic Ejection Tract Using 4d Flow in Patients with a Bicuspid Aortic Valve: Impacts on Aortic Regurgitation Assessment Open
View article: Four-dimensional flow cardiovascular magnetic resonance aortic cross-sectional pressure changes and their associations with flow patterns in health and ascending thoracic aortic aneurysm
Four-dimensional flow cardiovascular magnetic resonance aortic cross-sectional pressure changes and their associations with flow patterns in health and ascending thoracic aortic aneurysm Open
View article: The fundamental mechanisms of the Korotkoff sounds generation
The fundamental mechanisms of the Korotkoff sounds generation Open
Blood pressure measurement is the most widely performed clinical exam to predict mortality risk. The gold standard for its noninvasive assessment is the auscultatory method, which relies on listening to the so-called “Korotkoff sounds” in …
View article: Novel Association of the NOTCH Pathway Regulator <i>MIB1</i> Gene With the Development of Bicuspid Aortic Valve
Novel Association of the NOTCH Pathway Regulator <i>MIB1</i> Gene With the Development of Bicuspid Aortic Valve Open
Importance Nonsyndromic bicuspid aortic valve (nsBAV) is the most common congenital heart valve malformation. BAV has a heritable component, yet only a few causative genes have been identified; understanding BAV genetics is a key point in …
View article: Systematic brain magnetic resonance imaging and safety evaluation of non-invasive ultrasound therapy for patients with severe symptomatic aortic valve stenosis
Systematic brain magnetic resonance imaging and safety evaluation of non-invasive ultrasound therapy for patients with severe symptomatic aortic valve stenosis Open
View article: Role of the advanced nurse practitioner within the vascular team: A qualitative study of vascular physicians and nurses
Role of the advanced nurse practitioner within the vascular team: A qualitative study of vascular physicians and nurses Open
Objective To assess the perception of Advanced Nurse Practitioners (ANP) by physicians and nurses in vascular medicine. As the status of ANP in France was recently enacted by law in 2018, we aimed to investigate physicians and nurses worki…
View article: Indoxyl-sulfate activation of the AhR- NF-κB pathway promotes interleukin-6 secretion and the subsequent osteogenic differentiation of human valvular interstitial cells from the aortic valve
Indoxyl-sulfate activation of the AhR- NF-κB pathway promotes interleukin-6 secretion and the subsequent osteogenic differentiation of human valvular interstitial cells from the aortic valve Open
IS promotes hVIC mineralization through AhR-dependent activation of the NF-κB pathway and the subsequent release of IL-6. Further research should seek to determine whether targeting inflammatory pathways can reduce the onset and progressio…
View article: Assessment of Takayasu's arteritis activity by ultrasound localization microscopy
Assessment of Takayasu's arteritis activity by ultrasound localization microscopy Open
French Society of Cardiology. ART (Technological Research Accelerator) biomedical ultrasound program of INSERM, France.
View article: Methods: Aortic wall deformation assessment by ultrafast ultrasound imaging: Application to bicuspid aortic valve associated aortopathy
Methods: Aortic wall deformation assessment by ultrafast ultrasound imaging: Application to bicuspid aortic valve associated aortopathy Open
Purpose: Aortic maximal rate of systolic distention (MRSD) is a prognosis factor of ascending aorta dilatation with magnetic resonance imaging. Its calculation requires precise continuous tracking of the aortic diameter over the cardiac cy…
View article: Association of Lipoprotein(a) Levels With Incidence of Major Adverse Limb Events
Association of Lipoprotein(a) Levels With Incidence of Major Adverse Limb Events Open
Importance High lipoprotein(a) (Lp[a]) levels are involved in the development of cardiovascular events, particularly in myocardial infarction, stroke, and peripheral artery disease. Studies assessing the Lp(a) levels associated with advers…
View article: Occurrence of Major Local Lower Limb Events in Type 2 Diabetic Patients with Lower Extremity Arterial Disease: Impact of Metformin
Occurrence of Major Local Lower Limb Events in Type 2 Diabetic Patients with Lower Extremity Arterial Disease: Impact of Metformin Open
View article: Place of the Advanced Practice Registered Nurse within the vascular team: a qualitative study of vascular medicine physicians and nurses caring for patients with peripheral artery disease
Place of the Advanced Practice Registered Nurse within the vascular team: a qualitative study of vascular medicine physicians and nurses caring for patients with peripheral artery disease Open
Introduction Advanced Practice Registered Nurses (APRNs) treat and diagnose diseases, counsel the public about health problems, manage chronic diseases, and participate in continuing education. In the cardiovascular field, Peripheral Arter…
View article: Evaluation of Takayasu's arteritis activity by ultrasound localization microscopy
Evaluation of Takayasu's arteritis activity by ultrasound localization microscopy Open
Objectives Use of sulphur hexafluoride microbubbles (MB) with ultrasound can provide arterial wall enhancement. The use of ultrafast imaging with MB super-localization offers the possibility of ultrasound localization microscopy (ULM) and …
View article: Elevated Lipoprotein(a) levels increase Major Adverse Limb Event
Elevated Lipoprotein(a) levels increase Major Adverse Limb Event Open
Background High lipoprotein(a) levels are involved in the development of cardiovascular events, as particularly in myocardial infarction, stroke, and peripheral artery disease. Studies assessing prognostic values of lipoprotein(a) levels o…
View article: Systematic search for the UBA1 mutation in men after a first episode of venous thromboembolism: A monocentric study
Systematic search for the UBA1 mutation in men after a first episode of venous thromboembolism: A monocentric study Open
View article: Adjusting D-dimer to Lung Disease Extent to Exclude Pulmonary Embolism in COVID-19 Patients (Co-LEAD)
Adjusting D-dimer to Lung Disease Extent to Exclude Pulmonary Embolism in COVID-19 Patients (Co-LEAD) Open
Objective D-dimer measurement is a safe tool to exclude pulmonary embolism (PE), but its specificity decreases in coronavirus disease 2019 (COVID-19) patients. Our aim was to derive a new algorithm with a specific D-dimer threshold for COV…
View article: Women Specific Characteristics and 1-Year Outcome Among Patients Hospitalized for Peripheral Artery Disease: A Monocentric Cohort Analysis in a Tertiary Center
Women Specific Characteristics and 1-Year Outcome Among Patients Hospitalized for Peripheral Artery Disease: A Monocentric Cohort Analysis in a Tertiary Center Open
Although women have lower age-standardized cardiovascular disease incidence, prevalence, and death-related rates than men, there are also reports indicating that women with cardiovascular disease receive less care, fewer investigations, an…
View article: Relationship between kalemia and intensive care unit admission or death in hospitalized COVID-19 patients: A cohort study
Relationship between kalemia and intensive care unit admission or death in hospitalized COVID-19 patients: A cohort study Open
View article: Twelve-months safety of valvosoft non-invasive ultrasound therapy (NIUT) in patients with severe symptomatic aortic valve stenosis: a first-in-human study
Twelve-months safety of valvosoft non-invasive ultrasound therapy (NIUT) in patients with severe symptomatic aortic valve stenosis: a first-in-human study Open
Background Despite overall favourable outcome of surgical and transcatheter aortic valve replacement (SAVR/TAVR) in patients with severe calcific aortic stenosis (CAS), not all patients are eligible for an invasive treatment1 because of to…
View article: Thrombus of the Aorta and SARS-CoV-2 Infection: Cause or Trigger?
Thrombus of the Aorta and SARS-CoV-2 Infection: Cause or Trigger? Open
Objective: Coronavirus disease 19 is a well-established cause of rare arterial thrombosis. Nevertheless, the exact mechanism of arterial thrombosis remains to be elucidated. We herein report the case of a large floating thrombus of the aor…
View article: 41P Testosterone level and severity of COVID-19 infection in ambispective cohorts: The TESTOVID study
41P Testosterone level and severity of COVID-19 infection in ambispective cohorts: The TESTOVID study Open